Exam Flashcards
Causative organisms in cystitis (3)
E. coli, klebsiella, pseudomonas
Most common causal bacteria in pyelonephritis
E. coli
Consequence of sustained bladder outflow obstruction?
Hypertrophy of detrusor, diverticulae, focus for stone formation
Erythroplasia of Queryat
SSC-in situ of the penis
Main driving force behind formation of interstitial fluid
Capillary hydrostatic pressure
Indication for potassium-sparing diuretics?
Correct the hypokalaemia caused by thiazides and furosemide
Mechanism of loop diuretics
Inhibit the triple co-transporter in the ascending loop of Henle by binding to the chloride site
Adverse effects of loop diuretics (2)
Hypocalcaemia
Hypokalaemia
Drugs whose toxicity is enhanced by furosemide (2)
Digoxin
Class III anti-dysrhymthics
Acid-base balance in loop diuretics is shifted towards…
Alkalosis- increased secretion of protons
Mechanism of action of thiazides
Block NaCl transporter in the distal tubule
Adverse effects of thiazides (3)
Hyperuricaemia
Hypercalcaemia
Hypokalaemia
Mode of action of aldosterone and eplerenone
Aldosterone antagonists
Two types of diabetes insipidus
Neurogenic and nephrogenic
Three benign renal lesions
Angiomyolipoma
Oncocytoma
Renal cysts
Wunderlichs syndrome
Renal haemorrhage caused by angiomyolipoma
Triad of renal cell carcinoma
Loin pain
Blood in urine
Renal mass
RCC arises from…
The proximal convoluted tubule epithelium
Treatment of priapism
Aspirate, adrenaline