Exam 3 - Visceral fluke - Fasciola hepatica Flashcards

1
Q

Genera that live in liver

A

Fasciola, Clonorchis, and Opisthorchis

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2
Q

Genera that live in SI

A

Fasciolopsis, Heterophyes, Metagonimus, and Echinostoma

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3
Q

Genera that live in lungs

A

Paragonimus

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4
Q

best studied trematode because of its large size

A

Fasciola

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5
Q

Fasciola is a common parasite of:

A

sheep and cattle, rarely found in humans

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6
Q

Adult fasciola reside in the:

A

gall bladder and bile ducts in the liver

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7
Q

cephalic cone

A

cone-shaped projection at the anterior end of fasciola

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8
Q

Eggs pass out of the ___ into the _____ & expelled with _______

A

liver

intestine

the feces

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9
Q

If the eggs reach water after being passed form feces:

A

unembryonated eggs complete their development into miracidium and hatch in 9-10 days in warmer weather

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10
Q

After hatching, the miracidium has about ___ in which to find a suitable _____ for further development; if not, _____

A

24 hr

snail host

they die

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11
Q

Upon penetrating a snail, miracidium metamorphoses into:

A

a sporocyst that gives rise to mother rediae which may give rise to daughter rediae

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12
Q

_____ in the brood chambers of the redia develop into _______

A

Germ balls

cercaria

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13
Q

____ emerge from the snail ____ after infection

A

Cercaria

5-7 wk

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14
Q

______ attaches to any _______ object, ______ and encyst as ______ on plants upon which sheep and cattle feed

A

Cercaria

aquatic

drop its tail

metacercaria

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15
Q

Humans become infected by eating:

A

contaminated plants, esp. salads

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16
Q

Juveniles excyst in the _____, penetrate the ______, and travel to _____ where they feed and attain ______________

A

duodenum

intestinal wall

liver

sexual maturity

17
Q

What are responsible for the pathology associated with fascioliasis

A

Migration of young worms to host liver and presence of worms in the bile ducts

18
Q

As larvae migrate to the bile ducts:

A

they cause traumatic damage as well as intense eosinophilic inflammation to the hepatic tissue

19
Q

In the bile ducts, the larvae cause ______ of the biliary epithelium, and ______ of the biliary wall ducts.

A

hyperplasia

hardening

20
Q

Acute fascioliasis

A

often seen in sheep

Due to ingestion of more than 10,000 metacercariae at once

21
Q

Symptoms in humans

A

head/backache, nausea, coughing, vomiting, fever, abdominal pain, obstructive jaundice

22
Q

Life span of adult flukes in humans may be:

A

5 to 10 years

23
Q

Diagnostoc tools:

A

Eggs in feces

24
Q

Treatment:

A

bithionol and praziquantel for 2 weeks

25
Q

Human infection occurs ______ but is confined to _______ regions

A

World wide

Sheep/cattle-raising

26
Q

Control/prevention

A

sheep & cattle feces should not be allowed near aquatic regions. Snail population should also be carefully monitored

27
Q

Oral sucker vs ventral sucker

A

Similar in size