exam 3: salivary glands Flashcards

1
Q

saliva is involved to some degree in all of the following functions
x10

A

speech
mastication
taste
swallowing
digestion
protection
buffering
antimicrobial action
maintenance of tooth integrity
soft tissue repair

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2
Q

protein thought to be necessary for growth and maturation and taste buds

A

gustin

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3
Q

this degrades starch in digestion

A

salivary amylase

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4
Q

prevents potential pathogenic bacteria from colonizing the mouth (most require an acidic pH)

microbrial acids

A

buffering

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5
Q

protein that raises pH of dental plaque after exposure to fermentable carbohydrates

A

sialin

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6
Q

hydrolyzes bacterial cell walls

A

lysozyme (antimicrobial action)

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7
Q

binds free iron and thereby deprives bacteria of an essential nutrient

A

lactoferrin (antimicrobial action)

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8
Q

causes bacterial clumping (agglutination)

A

salivary IgA (antimicrobial action)

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9
Q

calcium and phosphate ions faciliate mineralization of tooth surface

A

maintenance of tooth integrity

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10
Q

epithelial growth factor
clotting factor

A

soft tissue repair

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11
Q

________cells dictate differentiation of oral epithelium which in turn proliferates and grows into the underlying mesenchyme.

the epithelial buds undergo histodifferentiation and morphodifferentiation to form assemblies of

A

ectomesenchymal cells

alveoli that devleop into acinar cells
and
epithelial cords that develop into ducts

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12
Q

stages of salivary gland development:
1
2
3
4
5
6

A
  1. induction of oral epithelium by underlying ectomesenchyme
  2. growth of epithelial cord
  3. initiation of epithelial cord branching
  4. repetitive branching and lobule formation
  5. canalization of the presumptive ducts
  6. cytodifferentiation to become acinar cells, myoepithelial cells, and ductal cells
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13
Q

last stage of salivary gland development is cytodifferentiation to become acinar cells, myoepithelial cells, and ductal cells with what two growth factors

A

FGF (fibroblast gf)
EGF (epidermal gf)

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14
Q

salivary glands-development and structure

FGF + EGF + terminal bulb cells ->

A

acinar cells
myoepithelial cells
duct cells

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15
Q

the parotid and submandibular glands begin to form during the _______ of embryonic development with the sublingual gland initiating development during the ______

A

6th week
8th week

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16
Q

the minor salivary glands begin to form by the ______ of embryonic development

A

10th week

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17
Q

hierarchy of ducts starting at the level of the secreting unit (acinus)

A

intercellular canaliculus
intercalated duct
striated duct
excretory duct (aka collecting duct)

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18
Q

associated with terminal end pieces (acini) and intercalated ducts

A

myoepithelial cells (aka basket cells)

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19
Q

stenson’s duct

A

parotid gland

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20
Q

wharton’s duct

A

submandibular gland

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21
Q

bartholin’s duct

A

sublingual gland

22
Q

PURE SEROUS secreting gland

A

parotid

23
Q

responsible for 20% of unstimulated salivary flow

A

parotid

24
Q

what occurs in mumps, sjorgens syndrome, bulimia nervosa, anorexia nervosa, benign and malignant neoplasia

A

salivary gland enlargement

25
Q

MIXED SEROMUCOUS gland
(mostly serous with mucous contributions)

A

submandibular gland

26
Q

responible for 60% of unstimulated salivary flow

A

submandibular gland

27
Q

MIXED MUCOSEROUS gland
(mostly mucous secreting)

A

sublingual gland

28
Q

responsible for 10% of unstimulated salivary flow

A

sublingual gland and also minor salivary glands

29
Q

most minor salivary glands are ____secreting

A

mucous

30
Q

minor salivary glands are:
1
2
3
4

A

von ebners
blandin-nuhn
webers
carmalts

31
Q

pure serous glands associated with circumvallate papillae

A

von ebner’s

32
Q

mucoserous glands located on ventral surface at tip of tongue

A

blandin-nuhn

33
Q

mucous glands associated with the pharyngeal tonsils

A

weber’s

34
Q

mucous glands found in the mandibular retromolar area

A

carmalt’s

35
Q

product secreted into blood and affects other cells; no duct system

A

endocrine
(classification of glands)

36
Q

secrete product onto a surface; usually has a duct

A

exocrine
(classification of glands)

37
Q

little/no damage to secreting cells (salivary glands)

A

(classification of glands)
merocrine

38
Q

partial injury to secreting cells (mammary/sweat glands)

A

(classification of glands)
apocrine

39
Q

total destruction of secreting cells (sebaceous glands)

A

holocrine

40
Q

not a pathologic lesion

represent ectopic sebaceous glands

A

fordyce’s granules
(fordyce spots)

41
Q

result of trauma that SEVERS the duct resulting in extravasation of mucin into the surrounding soft tissues

A

salivary gland mucocele

42
Q

where are the most common site of occurrence in salivary gland mucocele

A

lips, tip of ventral surface of the tongue and soft palate

43
Q

this is characterized by an accumulation of mucin containing numerous foamy histiocytes surrounded by granulation tissue

A

salivary gland mucocele

44
Q

term used to designate a mucocele that occurs in the floor of the mouth.

most often involve the sublingual salivary gland

A

ranula

45
Q

chronic, systemic autoimmune disease
80-90% of cases occur in middle aged females
xerostomia, xerophthalmia or keratoconjuctivitis sicca

-parotid gland swelling due to lymohocytic and plasma cell infiltrate

A

Sjogren’s syndrome

46
Q

benign tumor that accounts for 53- 77% of parotid gland tumors

44-68% submand

38-43% minor salivary gland tumors

A

mixed tumors aka pleomorphic adenoma

47
Q

well circumscribed (restrictive) and encapsulated
-tissue derived from mixture of ductal and myoepithelial cells
-keratinizing squamous cells and mucous producing cells are also present

A

mixed tumor aka pleomorphic adenoma

48
Q

one of the most common salivary gland malignancies

A

mucoepidermoid carinoma

49
Q

mucoepidermoid carcinoma most commonly involves what gland:

(facial nerve palsy may develop)

A

parotid

50
Q

composed of a mixture of mucous producing cells and squamous epidermoid cells.

abudant cellular pleomorphism and a tendency to form cystic areas within the tumor cell mass

A

mucoepidermoid carcinoma