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Biochemistry I > Exam 3 Practice > Flashcards

Exam 3 Practice Flashcards

1
Q

What does Caffeine and Cola do?

A
  • Inhibits phosphodiesterase activity
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2
Q

Aspartate is transaminated to _____ to get Glutamate

A
  • Alpha-ketoglutarate
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3
Q

What is the intermediate in the GP shuttle?

A
  • DHAP
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4
Q

What lipoprotein is reduced in the glycogen-phosphate shuttle?

A
  • Coenzyme Q
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5
Q

The conversion of NADPH to R5P is via

A
  • Steroid hormones
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6
Q

A deficiency of HGPRT results in

A
  • Lesch-Nyhan Syndrome
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7
Q

What is the inhibitor of the rate-limiting step in the PPP?

A
  • NADPH
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8
Q

What is the cofactor required by transketolase?

A
  • Thiamine pyrophosphate (TPP)
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9
Q

What is found in tea leaves?

A
  • Theophylline
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10
Q

Which of the following is a nucleoside?

A
  • Adenosine
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11
Q

What is NOT a function of nucleotides?

A
  • Primary energy source
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12
Q

What is the rate-limiting step of purine biosynthesis?

A
  • PRPP glutamyl transferase
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13
Q

What inhibits adenylsuccinate dehydrogenase?

A

-

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14
Q

What is the end product of purine biosynthesis?

A
  • Uric acid
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15
Q

What is a precursor of both pathways?

A
  • PRPP synthetase
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16
Q

What is the N3 and N9 amino acid?

A
  • Glutamine
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17
Q

What amino acid is not part of P nucleotide biosynthesis?

A
  • Glutamate
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18
Q

What is the treatment for gout?

A
  • Colchicine
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19
Q

What is the precursor to gout?

A

-

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20
Q

The rate- limiting enzyme in pyrimidine nucleotide biosynthesis

A
  • Carbamoyle phosphate synthetase II (CPS-II)
21
Q

Which amino acid helps with the reaction to CP?

A
  • Glutamine
22
Q

What inhibits CP-II?

A
  • UTP
23
Q

What enymatic defect results in orotic anemia?

A
  • OP transferase
24
Q

Which is not a KB?

A
  • Alanine
25
Q

Where are ketones not used?

A
  • The liver
26
Q

Statins inhibit

A
  • HMG reductase
27
Q

What is ketoacidosis?

A
  • Type I DM
28
Q

KB RL

A
  • HMG synthase
29
Q

What increases glu flux?

A
  • Ketogenesis
30
Q

A high insulin/glucagon ration results in

A
  • Insulin secretion
31
Q

Core of lipoprotein

A
  • Cholesterol ester
32
Q

Cholesterol carbons come from

A
  • Acetyl-CoA
33
Q

Active vitamin cholesterol

A
  • 1,25 cholecalciferol
34
Q

What is not a function of cholesterol?

A
  • Energy substrate
35
Q

RL of cholesterol

A
  • HMG-Co reductase
36
Q

Cholesterol takes place in

A
  • Cytoplasm
37
Q

The rate-limiting step ending

A
  • Mevalonic acid
38
Q

Rate-limiting step of bile acid production

A
  • 7-alpha-hydroxylase
39
Q

RL process cholesterol

A
  • AMP kinase
40
Q

Eicosanoid signal transduction

A
  • G-protein
41
Q

Arachadonic acid

A
  • Linoleic acid
42
Q

RL of eicosanoid

A
  • Phospholipase A2
43
Q

Aspirin inhibits

A
  • COX
44
Q

Housekeeping enzyme

A
  • COX-I
45
Q

High amount in MI

A
  • Thomboxane
46
Q

Endothelial cell vasodilation

A
  • Prostacyclin
47
Q

Glycine and cholic acid

A
  • Glycocholic acid
48
Q

Favism

A
  • G6PDh
49
Q

Ketogenesis

A
  • Prolonged starvation

Biochemistry I (34 decks)

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