Exam 3 Oakley Flashcards
Antidepressants drug of choice is?
SSRI is always drug of choice
(Prozac/Zoloft)
Valium (diazapam) used for everything except?
used for everything EXCEPT analgesic
Main drug for status elipitus
Valium (diazapam)
SSRI definition
serotonin reuptake inhibitors – and that is they increase neutrophic factor for
helping the neurons
antihistamines don’t work well if you already have congestion soooo use
pseudofed!!!
AKA Pseudoephedrine -a vasConstrictor
how does levadopa work?
levadopa tries to get dopamine into brain thru BBB; carbadopa inhibits carboxylase so it doesn’t get metabolized before L-dopa gets to brain
parkinsons is in what part of brain?
basal ganglia
what med you don’t want to give local with epi bc its an inhibitor?
Slegritine (aldipril)
*use 3% mepivicaine
dopamine agonist #1 side effect
orthostatic hypotension
prescribe benzo therapeutically for?
anxiety, muscle spaama, insomnia
*NOT for allergic rhinitis
benzo overdose give?
flumazenil (Romazicon)
pregnant insomnia use?
antihistamine diphenhydramine (Benadryl)
what is the benzo of choice for ppl with alcohol withdrawal?
lorazepam (Ativan)
what benzo has burning mouth syndrome?
clonazepam (Klonopin)
phenytoin (Dilantin) works as a?
Na+ channel blocker
*same as local and carbamazepine/Tegretol
valproic acid (Depakote) works by?
Na+. and GABA
does not block Calcium
dantrolene (Dantrium) treats what? How?
treats Malignant hyperthermia (neuromalignant problem)
*works by binding ryodine receptors in the muscle and blocks Ca so you don’t get the troponin and myosin doesn’t bind to actin
SSRI are used to treat depression etc, but NOT used for?
motion sickness
what happens when a pt takes benzo (1st generation histomine)? antihistamine (benadryl)?
sedation
two main side effects of parkinson drugs?
1) dry mouth
2) orthostatic hypotention
how does carbamazepine/Tegretol work?
Na channel blocker
*just like LA and phenytoin (Dilantin) *
skitzophrenic pt side effects
sex dysfunction, anticholinergic, bind alpha 1, TMJ discomfort
no excessive salivation
skitzophrenic pt side effects
sex dysfunction ANTIcholinergic bind alpha 1 TMJ discomfort GI/nausea ortho hypotention dry mouth
no excessive salivation bc that is a cholinergic problem
why take famotidine (Pepcid)?
ulcer***
GI prob
heart burn
Got a schizophrenic male, adolescent – what is the best drug for him to take?
risperidone (Risperdal)an atypical antipsychotic
what is a side effect we WON’T have for antidepressants such as SSRI?
weight loss
haloperidol (Haldol) is a drug for?
tourettes syndrome
what is cimetidine (Tagamet) not used for?
- Histamine 2 receptor antagonist
- OTC
- hepatic enzymes
ANSWER is: H1 antagonist used for allergic rhinitis (runny nose)
aripiprazole (Abilify) is NOT used for?
NOT used for Parkinsons
*used for antipsychothic and antidepressants
28 year old taking lithium, what drug don’t want to prescribe?
do not prescribe NSAIDS (or thiazide)
- tylonal is NOT an NSAID
- thiazide but we don’t presicribe that
Main H1 antagonist, main cause of sedation?
diphenhydramine (Benadryl)
what drugs you’d use to treat insomnia
DO NOT USE ropinirole (Requip) -bc it is a dopamine agonist
You would use: zolpadin, ambien, Lunesta, rosarium
why is lamotrigine (Lamictal) bad? two things!
STEVEN JOHNSONS syndrome - toxic epidermal necrolysis
*good bc mood stabolizer
when you see ‘epileptic drug treating TRIGEMINAL neuralgia’ think?
carbamazepine (Tegretol)
main gingival hypertension caused by?
phenytoin (Dilantin)
how do antihistamines work?
block histamine receptors
carbamazepine (Tegretol) treats?
epileptic drug treating TRIGEMINAL neuralgia
Gave you a drug that was neuroprotective – found in studies over 7-8 years in parkinsons, and it was to
MAOB inhibitor – what metabolite did it protect against
DOPAMINE TO DOPAL!!! Know DOPAL
typical and atypical anti-psychotics work for
typical= GOOD on positive= 1st generation
atypical= works goof on Negative- 2nd generation
how do antihistamines work?
block histamine receptors
*do NOT work on dopamine
Drug of choice or malignant hyperthermia
dantrolene (Dantrium)
Which one of these drugs is a dopamine agonist
Pramapaxoll/Mirapex ***
a. Amanatainde - odd ball drug – anti-viral
b. Levadopa – dopamine precursor
c. Benzatropine - benza
d. Pramapaxoll/Mirapex – have two questions on that
e. Tocapone – COMT
a drug to treat chronic pain of neuropathic origin?
amitriptyline (Elavil)
What percent of patients have gingival hyperplasia with phenytoin?
50%
main mood stabolizers?
valproic acid (Depakote) and litheum
psychosis
CNS disorder -loss of reality
