Exam 3 - musculoskeletal pathology

Question 1

OA: primary vs secondary

Answer 1

primary = unknown cause

secondary= known cause (trauma, malformations, etc)

Question 2

OA: Heberden’s vs Bouchard’s nodes

Answer 2

Heberden’s = at the DIP

Bouchard’s = at the PIP

Question 3

Knee OA criteria

Answer 3

• persistent pain
• limited morning stiffness
• reduced function
• crepitus
• boney enlargement
• restricted movement

Question 4

RA: pathology

Answer 4

• immune cells into synovial
• thickens
• dec joint lube and articular cartilage nutrition
• weakens the joint

Question 5

RA: swan neck vs boutonniere deformity

Answer 5

Swan = extend PIP, flex DIP

Boutonniere = flex PIP, extend DIP

Question 6

1) onset > 40 yrs

2) onset btwn 25-50 years

Answer 6

1 = OA
2= RA

Question 7

1) onset over weeks to months, intermittent exacerbation and remission
2) gradual onset over years

Answer 7

1=RA

2=OA

Question 8

1) 1-2% of US adults

2) 12% of US adults

Answer 8

1= RA

2=OA

Question 9

1) Men > women under 50. Women > after 50

2) women 3:1 to men

Answer 9

1= OA

2 = RA

Question 10

1) synovial fluid has low WBC

2) synovial fluid has high WBC

Answer 10

1 = OA

2=RA

Question 11

1) can affect any joint, usually UE > LE. often bilateral, symmetrical presentation
2) can affect a single joint or any combination of joints

Answer 11

1 = RA

2=OA

Question 12

1) inflammation and stuff present for 10% of cases

2) inflammation almost always present

Answer 12

1 = OA

2= RA

Question 13

1) Brief morning stiffness

2) prolonged morning stiffness lasting > 1 hour

Answer 13

1 = OA

2 = RA

Question 14

1) pain at rest and with activity

2) usually pain only with activity

Answer 14

1= RA

2= OA

Question 15

1) systemic presentation with constitutional symptoms (fever, malaise, wt loss)
2) no systemic symptoms

Answer 15

1 = RA

2 = OA

Question 16

pseudogout

Answer 16

-calcium pyrophosphate dihydrate crystals in joints and synovial fluid

Question 17

Gout

Answer 17

urate crystals in joints.