Exam 3: Digestive System Flashcards
Masticatory mucosa is found on
Gingiva and hard palate
Surface epi of oral mucosa
Keratinized/parakeratinized strat squamous
Superficial cells of parakeratinized strat squamous epi keep their
Nuclei
Lamina propria of oral mucosa made up of 2 layers
Papillary layer
Reticular layer
Surface epi of lining mucosa
Strat squamous
**occasionally parakeratinized
Epithelium of vermillion zone of lips
Keratinized strat squamous
Submucosa of lining mucosa in oral cavity made up of
Dense CT
Can have glands, BV and nerves
Specialized mucosa is found on
Dorsal surface of tongue
Keratinized strat squamous epi is found on ___ papilla
Filiform
Strat squamous epi is found on ____ papilla
All other (except filiform)
General functions of specialized mucosa
Move food
Taste
Mucosa of the tongue is thicker ____ and thinner/smoother on _____
Dorsally; lower surface
Small salivary glands are associated w/
Vallate papilla
Function of small salivary glands
Produce serous fluid to cleanse tastebuds
Taste buds are located on all papilla except
Filiform papilla
Submucosa of tongue contains
Lingual salivary glands
Intrinsic tongue muscles have no ____ and are _____ muscles
External attachment; skeletal
4 alternating intrinsic tongue muscles from top to bottom
Superior longitudinal
Vertical muscles alternate w/ transverse
Inferior longitudinal
Function of intrinsic tongue muscles
Change tongue shape
Ameloblasts are polarized ____ cells
Columnar
You lose ameloblasts following
Tooth eruption
Function of ameloblasts
Produce enamel
Hardest substance in the body
Enamel
After tooth eruption, you cannot make more ___
Enamel
___ is harder than bone
Dentin
Dentin contains thin dentinal tubules w/ nerves and cell processes of
Odontoblasts
Precursor to dentin before mineralization
Perdentin
Columnar cells lining pulp cavity
Odontoblast
Function of odontoblasts
Repair
Produce/maintain dentin
Dental papilla AKA
Dental pulp
Dental papilla is CT w/ many
Blood vessels and nerves
Potential problem w/ dental papilla
Extensive inflammation
Largest salivary gland that only produces about 30% of total salivary output
Parotid gland
Gland most affected by the mumps
Parotid gland
Parotid gland is 100% ___ producing
Serous
Parotid gland products secreted
Salivary amylase
Lysozyme
Sec IgA
Function of salivary amylase
Break down carbs
Submandibular gland produces ___% of total salivary output
60%
Submandibular gland is a ___ gland, producing ___ and ___
Mixed gland; Mucus and serous products
Sublingual gland produces ___ of total salivary output
5%
Sublingual gland is a ___ gland, producing ____ and ____ products
Mixed; mucus and serous products
Sublingual gland is ___% mucus producing
80%
Para impulses increase the amount of ___ secretion from salivary glands
Watery
Sympathetic impulses decrease the amount of a saliva with a ____ consistency
Thicker
Submucosa of gut luminal walls includes ____ plexus
Submucosal (Meissner)
Muscularis externa of gut luminal wall contains ___ plexus
Myenteric
Surface epi of esophagus
Strat squamous
Contains Langerhans cells
Lamina propria of esophagus can have
Esophageal cardiac glands
Function of esophageal cardiac glands
Produce neutral mucus to protect esophageal epi
Location of esophageal cardiac glands in esophagus
First inch (by pharynx) Last inch (by stomach)
Muscularis mucosa in esophagus is a ___ layer of long smooth muscle
Discontinuous
Submucosa of esophagus contains
Esophageal (proper) glands
Function of esophageal glands
Produce mucus to lubricate passage of food
Muscularis externa of esophagus
Upper 1/3 = skeletal
Middle 1/3 = mixed
Lower 1/3 = smooth
Adventitia/serosa of esophagus: primarily ___ except the last ____
Adventitia; last 1-2 inches = serosa
Pharyngoesophageal sphincter is between
Oropharynx and esophagus
Gastroesophageal sphincter is between
Esophagus and stomach
For physiological sphincter there is no thickening of
Circular muscle in ME
Barrett’s esophagus: strat squamous epi is replaced by
Mucus-secreting simple columnar epi
Primary function of stomach
Food storage
Nutrient breakdown in stomach is primarily ___
Chemical
Little physical
Gastric pits
Depressions in stomach’s surface
1 pit leads to >1 gland
Surface epi of stomach
Simple columnar
Functions of surface mucus in stomach mucosa
Produce thick mucus
Secrete bicarb ions
Muscularis mucosa in stomach often has 3 layers
- Inner circular
- Outer longitudinal
- Outermost circular/oblique
Submucosa of stomach is the location of AVA which functions to
Shut down activity and secretion FAST
Submucosal plexus in stomach is next to ____ layer of muscle
Inner circular
Muscularis externa of stomach has 3 layers
- Innermost oblique
- Middle circular (well-developed)
- Outer long. (Thin)
Myenteric plexus in stomach is between
Circular and long. Layers of musclularis externa
Layer outside of muscularis in stomach is all ____
Serosa (no adventitia)
Gastric region of stomach contains gastric glands which extend from
Gastric pit to MM
Surface mucus in isthmus of gastric gland function
Protect from acids and enzymes
DNES cells in gastric gland
Type D
Type EC
Type G
Type D DNES cells in gastric gland
Produces Somatostatin
Type EC DNES cells in gastric gland
Produces serotonin and substance P
Type G DNES cells in gastric gland
Produce gastrin: stims HCl and pepsinogen secretion
Parietal cells in the neck of gastric gland produce
Very strong HCl Intrinsic factor (B12 absorption)
Chief cells in gastric glands produce
Pepsinogen (primarily)
Gastric lipase
Pyloric sphincter is an ___ sphincter between the
Anatomical; pylorus and duodenum
Anatomical sphincters have a well developed _____ that can be ________
Inner circular layer; independently controlled
2 general causes of peptic ulcer disease
Insufficient protection
Helicobacter pylori
Some factors that delay healing of peptic ulcer disease
Smoking Alcohol Caffeine Calcium Aspirin
2 surface adaptations in SI to inc surface area
Plicae circulares
Villi
Microvilli
Surface epi of SI
Simple columnar
Main function of surface absorptive cells in SI
Absorb water and nutrients
Goblet cells in SI the fewest are in the ___, most in the ____
Duodenum; ileum
Type I DNES cells in SI
Produce CCK — stim gallbladder and pancreas secretion from serous acini
Type S DNES cells in SI produces secretin which
Stims pancreas secretion of bicarb
Inhibits HCl release and chyme movement
Paneth cells in SI are found at ______ and they produce _____
Bases of crypts; lysozyme
M cells in SI are found in
Ileum epi over Peyer’s patches
General function of M cells =
Humoral immunity
Important in maintaining gut flora
LP of SI contain lacteals which are ____ that function in _____
Lymphatic capillaries; lipid absorption
Duodenum contains ____ glands which produce _____
Duodenal/Brunner’s; alkaline mucus
Significance of each part of SI
Duodenum = Brunner’s glands Jejunum = nothing Ileum = Peyer’s patches
Peyer’s patches are only found in
Ileum
Function of myenteric plexus in SI
Stim ME for peristalsis
Serosa is found covering which parts of SI
Jejunum and ileum, 1st and last parts of duodenum
Adventitia is found covering which parts of SI
Descending portion of duodenum
Ileocecal valve is found between _____ and is a _____ sphincter
Ileum and cecum of colon; physiological and anatomical sphincter
Appendix surface epi
Simple columnar
Mucosa characteristics in appendix
Short crypts
No villi
No Paneth cells
Submucosa of appendix contains numerous
Lymph nodules
Functions of appendix
Humoral immunity
Reservoir for good bacteria
Primary function of colon
Absorption of water
Surface epi of colon
Simple columnar w/ many goblets
Mucosa of colon lacks
Villi
Paneth
Muscularis externa of colon is not normal pattern:
Outer longitudinal ms in bands called teniae coli
Constant tonus of teniae coli results in
Haustra
All parts of colon have ____ adventitia/serosa
Mixed
Some adventitia, mostly serosa
Surface epi of rectum
Simple columnar
Notable features of rectum
Transverse rectal folds
No teniae coli
Adventitia
Covering of rectum is
Adventitia
Surface epi of anal canal
Strat squamous
Simple columnar quickly transitions
Internal anal sphincter is a thick circular layer of ____ within ____
Smooth muscle; ME
External anal sphincter contains
Levator ani
External anal sphincter is ___ muscle from ____
Striated; pelvic floor
Luminal wall covering of anal canal
Adventitia