Exam 2: Urinary Flashcards
Capsule of kidney
Thin/fibrous
Dense irregular CT
Renal pelvis
Widening of ureter
Major calyces
Broad spaces to collect urine — direct to renal pelvis
Minor calyces
Smaller collecting areas from each major calyx
Minor calyces contain
Renal papilla
Renal papilla is the
Tip of each renal pyramid
Renal sinus
Area surrounding renal pelvis, major/minor calyces
Renal sinus contains
Adipose
Components of renal cortex
Renal corpuscles
Tubules
Meudllary rays
Medullary rays extend from
Medulla into cortex
Primary portions of medullary rays
Loop of Henle and collecting tubules
Components of medulla
Renal pyramids
Renal columns
Renal pyramids
8-12/kidney
Parallel nephrons
Collecting ducts
Renal columns are areas separating the
Renal pyramids
Renal columns have
BV
Urinary tubes
Fibrous CT
General function of renal corpuscle
Blood filtration
3 parts of renal corpuscle
Bowman’s capsule
Glomerulus
Mesangial cells
Bowman’s capsule layers
Parietal layer
Visceral layer
Urinary space between
Parietal layer of Bowman’s capsule epithelium
Simple squamous
Visceral layer of Bowman’s capsule
Internal layer of podocytes
Urinary space receives filtered fluid from
Capillaries
Where is filtrate first collected
Urinary space (btw layers of Bowmans capsule)
Podocytes
Modified epi cells
Contain pedicels
Pedicels
Cover glomerular capillaries
Create filtration slits
Glomerulus
Fenestrated capillary network in visceral layer of Bowman’s
Glomerulus has a thick ___ which functions to ____
Basement membrane
Block large proteins
Glomerulus is located btw 2 arterioles so that
Tunica media can inc pressure to enhance filtration
Mesangial cells
Cells in renal corpuscles
Pericyte-like
Mesangial cells are present in areas lacking __
Podocytes
Functions of mesangial cells
Support
Filtration
Phagocytosis
Secrete cytokines
Proximal convolutes tubules epithelium
Simple cuboidal w/ long microvilli
Location of PCT
Cortex
Proximal straight tubule epi
Simple cuboidal
NO microvilli
Proximal straight tubule location
Medulla
Thin limbs consist of
Descending and ascending parts
Thin limbs epi
Simple squamous
Location of thin limbs
Medulla
Thick ascending limb epi
Simple cuboidal
NO microvilli
Distal convoluted tubule epi
Simple cuboidal
Shorter cells
Shorter/fewer microvilli
DCT location
Cortex
Macula densa is part of ___ at the vascular pole containing ____
DCT; closely packed columnar cells
Macula densa is part of the
Juxtaglomerular apparatus (JGA)
Connecting tubule epi
Simple squamous/cuboidal
Function of connecting tubule
Connect nephrons to collecting ducts
Are collecting ducts part of a nephron
NO
Collecting duct epi
Simple cuboidal to simple columnar
Cell types in collecting ducts
Principle cells
Intercalated cells
Principle cells AKA
Light cells
Collecting duct cells
MC cell type
Location of principle cells
Medullary rays and medulla
Intercalated cells AKA
Dark cells
Intercalated cells location
Medullary rays
There are no intercalated cells close to
Renal papillae
Collecting ducts lead to ___ which lead to ____ and finally to ____
Papillary duct; renal papillae; minor calyx
Mucosa is the major layer lining the
Lumen
3 sublayers of mucosa
Epi
Lamina propria
Muscularis mucosae
Luminal wall layers of ureter, urinary bladder, and urethra
Mucosa
Submucosa
Muscularis externa
Adventitia
Lamina propria
Loose CT w/ small BV
Lymphatics
Nerves
Glands
Muscularis mucosae
Longitudinal smooth ms
Discontinuous
Wall strength
Thickness varies
Submucosa
Fibrous CT layer
Strength
Larger BVs
Glands possible
Muscularis externa
Usually smooth ms
Normal pattern of muscularis externa
Inner circular
Outer longitudinal
Adventitia
CT on outside of ME
Binding function
Serosa is an edge of ____ cells outside of ME
Squamous
Serosa can secrete a
Serous fluid
Lubrication function
Epi of ureters
Urinary epi
Luminal wall mucosa has 3 layers:
- Basal cells
- Intermediate cells
- Large superficial cells
LP of ureters
Dense irregular CT
Submucosa of ureter blends w/
LP
Muscularis externa of ureter has a reverse pattern
Inner longitudinal
Outer circular
Distal end of uretery has 3 muscle layers
Inner longitudinal
Middle circular
Outer longitudinal
Ureter enters at an angle to create a ___, as bladder fills ____
Valve; entrance to ureters is closed
Function of valve ____ which is important to ____
Prevent backflow; stop spread of infection to kidneys
Bladder mucosa epi
Transitional = urothelium
Function of urothelium in mucosa of bladder
Stretch and protect from hypertonic/toxic urine
Transitional epi has one layer of superficial cells called
Umbrella cells
Purpose of plaque on urothelium of bladder
Protection of cells/tissues
Block water passage
Muscle making up urinary bladder
Detrusor
Urinary bladder has a ___ pattern of ME
Reversed
Long
Circular
Long
Internal urethral sphincter is a
Circle of smooth muscle
Internal urethral sphincter is under ____ control
Involuntary
Sympathetic to bladder supply
Blood vessels
Parasympathetic in bladder supply
ME and adventitia
Micturation reflex
Sensory neurons in urinary bladder
Afferent fibers for micturition reflex
Urethra is a fibromuscular tube with
Longitudinal folds in mucosa
3 sections of male urethra
Prostatic
Membranous
Spongy
Prostatic urethra surface epi
Urothelium
Membranous urethra passes through
External urethral sphincter
External urethral sphincter made up of
Skeletal muscle
Membranous urethra epi
Stratified columnar
Pseudostratified columnar
Spongy urethra is surrounded by
Erectile tissue
Surface epi of spongy urethra
Strat columnar
Pseudostrat columnar
Strat squamous
Glands that empty into spongy urethra
Bulbourethral and urethral
In males the urethra is part of what systems
Urinary and reproductive
In females urethra is part of which system
Urinary only
Surface epi of female urethra
Transitional
Strat/pseudostrat columnar
Strat squamous
External urethral sphincter is around _____ of female urethra
Middle portion