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CDM1 > Exam 3: Asthma > Flashcards

Exam 3: Asthma Flashcards

1
Q

Abbrev to know: DPI

A

Dry powder inhaler

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2
Q

Abbrev to know: EIB

A

Exercise induced bronchospasm

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3
Q

Abbrev to know: HFA

A

Hydrofluoroalkane

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4
Q

Abbrev to know: ICS

A

Inhaled corticosteroids

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5
Q

Abbev to know: LTRA

A

Leukotriene Receptor Antagonist

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6
Q

Abbev to know: LABA

A

Long acting beta2 agonist

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7
Q

Abbev to know: LAMA

A

Long acting muscarinic antagonist

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8
Q

Abbev to know: MDI

A

Metered dose inhaler

HFA is a type of MDI, will be used interchangeably

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9
Q

Abbev to know: OCS

A

Oral corticosteroids

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10
Q

Abbev to know: SABA

A

Short acting beta2 agonist

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11
Q

Abbev to know: SAMA

A

Short acting muscarinic antagonist

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12
Q

Abbev to know: SMI

A

Soft mist inhaler

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13
Q

Asthma med term: wheeze

A

high pitched noise usually heard upon exhalation

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14
Q

Asthma med term: “Personal Best” Peak Expiratory Flow

A

highest peak flow reading you can achieve when your asthma is under good control; used in conjunction with an asthma action plan to assess severity and guide therapeutic decisions

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15
Q

Astham med term: Exercise induced bronchospasm (EIB)

A

Exercise-induced bronchospasm which can be pre-treated with certain bronchodilators

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16
Q

Asthma med term: Bronchial Hyper-responsiveness (BHR)

A

Increased sensitivity of the airways to narrow in response to various stimuli

17
Q

Asthma med term: Atopy

A

a genetic predisposition for the development of IgE-mediated response to common aeroallergens

Eczema
AR
Allergic Conjunctivitis

18
Q

Asthma Phenotypes (5)

A
  1. allergic asthma
  2. non-allergic asthma
  3. Adult-onset asthma
  4. Asthma with persistent airflow limitation
  5. asthma with obesity
19
Q

Asthma RF: Host factors

A

Innate immunity (hygiene hypothesis)
Genetics
Age (younger)
Sex

20
Q

Asthma RF: Environmental factors

A

Allergens (animal dander, cockroach allergen, house dust-mite)
Pollution (occupational, environmental, tobacco)
Infections
Microbes
Stress

21
Q

Asthma RF: Other

A

Ethnicity
Urbanization
Socioeconomic status

22
Q

Pathophysiology

A

TH2&raquo_space; generates cytokines (IL4, IL5, IL13) + stimulate B lymphocytes to produce IgE antibodies&raquo_space; activate mast cells&raquo_space;release eosinophil&raquo_space; release inflammatory mediators (histamine, PG and LT)

23
Q

Features less likely to be asthma

A

Isolated cough with no other respiratory symptom, chronic sputum production, SOB associated with dizziness, light headedness, peripheral tingling, or exercise-induced dyspnea w noisy inspiration

24
Q

FENO Tests

A

Useful in supporting asthma diagnosis and indicating Type 2 (T2) inflammation of airway
FENO >50 ppb (or >35ppb in children 5-12) support diagnosis of asthma and indicate T2 inflammation
Levels impacted by smoking and atopic conditions

CDM1 (19 decks)

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