Exam 1: Vitamins Flashcards
Vitamin A: Use
Eyesight (AMD/cataracts)
Vitamin A: 2 Types and names
- Retinol (preformed)
2. Beta-carotene (pro-vitamin)
Vitamin A: Dosing - UL
UL: 3000 mcg (preformed vitamin A) – avoid high doses if pregnant (birth defects)
Vitamin A: Adverse effects
Yellow skin (too much beta-carotene, harmless) Hepatotoxicity Birth defects (retinol)
Vitamin B1: Name
Thiamin
Vitamin B1: Use
Alcoholic dependency
Wernicke’s encephalopathy
Vitamin B2: Name
Riboflavin
Vitamin B2: Uses
Migraines
Cataracts
Vitamin B2: Adverse effects
Diarrhea when used in large doses (>400mg for migraines)
Vitamin B3: Name
Niacin
Vitamin B3: Use
Cholesterol
Increases HCL
Decreases TG, LDL
Vitamin B3: Dosing
Cholesterol: 1-3g daily
Vitamin B3: Adverse Effects
Glucose intolerance
>50mg: Flushing/itching/headache
>1.5g: hepatotoxicity
Vitamin B6: Name
Pyridoxine
Vitamin B6: Use
Pregnancy induced nausea/vomiting
Vitamin B6: Dosing
10-25mg TID or QID (<100mg/day)
Vitamin B6: Adverse effect
Sensory neuropathy at doses >200mg
Vitamin B6: Other info
Decreases folic acid conc.
Antiepileptics may cause vitamin B6 deficiency
Vitamin B9: Name
Folate (Folic acid)
Vitamin B9: Uses
Neural tube defects
Alcoholic dependency
Vitamin B9: Dosing
Prevention of neural tube defects: 400mcg DFE (increase to 600mcg DFE when pregnancy is confirmed)
Vitamin B9: Warning with vitamin B12
Folic acid masks some s/sx of pernicious anemia resulting in neurologic deficiency if B12 deficient
Vitamin B9: Other drug interactions
Folic acid masks s/sx of pernicious anemia (B12 deficiency!)
May decrease effectiveness of methotrexate when used for cancer
Antiepileptics may reduce folate levels
Vitamin B12: Name
Cyanocobalamin
Vitamin B12: Use
Older adults
Pernicious anemia
Vitamin B12: Dosing equivalence
PO equivalent to IM
Vitamin B12: What decreases B12 ABSORPTION
PPIs and H2 receptor blockers
Vitamin B12: What decreases B12 LEVELS
Metformin
Vitamin B12: Drug interactions
PPIs, H2 blockers (Acid suppression decreases B12 absorption)
Metformin (decreases B12 levels)
Vitamin C: Name
Ascorbic acid