Exam 3 Flashcards

1
Q

Azelastine (Astelin)

A
Nasal spray
Antihistamine 
c & P histamine H1 receptors = MOA
Preg: C
>5y.0 PEDS
mild, intermittent, sevre rhinitis
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2
Q

Ipratropium Bromide (Atrovent)

A
Nasal Spray
Anticholinergic
antagonizes acetylcholine receptors
Preg: B
Lac. Safe
PEds >5y.o.
used for thick boggy nasal membranes and rhinitis
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3
Q

Phenylephrine (NEO synephrine)

A

nasal spray
decongestant
stimulates alpha adrenergic receptors PRODUCING VASOCONSTRICTION (sympathomimetic)
Preg: C
Peds >6
used in nose bleeds and nasal / sinus stuffiness . dont use long term cause necrosis

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4
Q

Oxymetazoline (AFRIN)

A

Nasal spray decongestant
stimulates muscle alpha adrenergic receptors PRODUCING VASOCONSTRICTION
Preg: C
>6y.o.
decongestant for nasal sinus stuffiness, can elevate BP but no necrosis

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5
Q

Fluticansone (flonase, veramyst)

A

nasal spray
corticosteroid
inhibits inflammatory cytokines, and produces glucocorticoid, and mineralocorticoid effects
bile
Preg: C
allergic/non allergic rhinitis + nasal polyps size reduction

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6
Q

Mometasone (nasonex)

A

Nasal spray
corticosteroid
inhibits inflammatoru cytokines and the effects
bile
Preg: C
allergic and non allergic rhinitis and nasal polyp size reduction

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7
Q

Triamcinolone

A

nasal spray
corticosteroid
inhibits inflammatory cytokines and the two different effects
bile
Preg: C
allergic and non allergic rhinitis and reduction in the size of nasal polyps

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8
Q

Penicillin

A

Narrow spectrum
Pen V, Pen G
for streptococcal pharyngitis, rheumatic fever staph infections

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9
Q

Pen VK

A
pneumococcal infection prophylaxis
watch for allergy and cephalosporin cross over
LOWERS SIEZURE THERSHOLDS 
Preg: B
cheap!
BCP - diminishes OC effects
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10
Q

Bicillin LA

A

Penicillins
bacterialcidal
inhibits cell wall synthesis
DO NOT ADMINISTER IV , OR ADMINISTER W/ OTHER SOLUTIONS = CARDIORESPIRATORY ARREST
THIS ALSO LOWERS SIEZURE THERSHOLD
Used: strep, syphilis - especially if pregnant, rheumatic fever

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11
Q

Amoxicillin

A

500 & 875 dosages
Treat sinusitis, otitis and strep pharyngitis.
LIMITED USE WITH DENTAL ABSCESSES = IT IS USUALLY CLINDA OR PEN VK
peds: CAP, strep
diarrhea in peds GI effects

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12
Q

Augmentin (amox + clauv.)

A

penicillins, aminopenicillins
bacterialcidal, inhibits cell wall mucopeptide synthesis, and inhibits beta-lactamases
Tx: Sinusitis, dog/cat bites

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13
Q

Cephalosporins

A

low toxicity
broad specturm
no for MRSA or MRSE
cross over with PCN

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14
Q

1 gen ceph

A

cefazoline (ancef) - bactericidal, inhibits mucopeptide synthesis, used for human bite injuries
cephalexin

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15
Q

2 gen ceph

A

cefuroxime (ceftin) - Preg: B

bactericidal, inhibits mucopeptide synthesis - used in pharyngitis, impetigo, sinusitis, and bacterial pneumonia

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16
Q

3 gen ceph

A

cephtriaxone

cefdinir (Omnicef) - bacterialcidal, inhibits mucopeptide synthesis, tx for secondary AOM

17
Q

4 gen ceph

A

cefepime

18
Q

Macrolides

A
inhibit 50S ribosomal unit
Azithromycin
Erythromycin
Clarithromycin
Clindamycin
GOOD ALTERNATIVES IN PCN ALLERGIC
covers atypical throat bacteria
otitis media!
19
Q

Clindamycin (Cleocin)

A
bactericidal/static depends on conc. 50S inhibitor
Pharyngitis, ENT, dental, facial
Good for MRSA
LACTATION UNSAFE
BBW - CAUSES C.DIFF - oral vanc.
20
Q

Gasping baby syndrome

A

from benzyl alcohol content in clindamycin so avoid use in neonates b/c the kids cannot convert alcohol ye and gradual neurologic deterioration occurs

21
Q

Levofloxacin (levaquin)

A

fluoroquniolone
inhibits DNA gyrase
BBW - tendinitis, tendon rupture
AVOID IN MYASTHENIA GRAVIS

22
Q

Ampicillin / sublactam (Unasyn)

A

penicillin / aminopenicillin
inhibits mucopeptides synthesis and beta-lactamases
USED FOR SIGNIFICANT INFECTIONS - SINUSITIS, PERIORBITAL OR PERITONSILLAR ABSCESS
Peds weight bases