Exam 2- RNA Viruses Flashcards

1
Q

All RNA viruses are ss EXCEPT

A

reoviruses

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2
Q

What does reovirus cause?

A

reovirus (cold/gastroenteritis)

rotovirus (gastroenteritis)

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3
Q

What does arenavirus cause?

A

LCMV (choriomeningitis)

Lassa Fever (hemorrhagic fever)

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4
Q

What does bunyavirus cause?

A

California encephalitis

Hantavirus (pulmonary syndrome)

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5
Q

What does orthomyxovirus cause?

A

Flu A & B

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6
Q

What are antibodies for influenza directed at?

A

HA

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7
Q

Antigenic drifts cause

A

epidemics

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8
Q

Antigenic shifts cause

A

pandemics

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9
Q

A sudden _____ is more deadly than a gradual ____.

A

Shift

Drift

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10
Q

What does filovirus cause?

A

Ebola

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11
Q

What does rhabdovirus cause?

A

Rabies

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12
Q

What is the mechanism for rabies?

A

binds to nicotinic ACh receptors in peripheral nerves

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13
Q

How is rabies diagnosed?

A

post mortem negri bodies in purkinje cells of cerebellum and hippocampal neurons

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14
Q

What does paramyxovirus cause?

A

measles

mumps

parainfluenza

RSV

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15
Q

What does parainfluenza virus cause?

A

croup

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16
Q

What does mumps cause?

A

parotitus

17
Q

What is the measles progression?

A
  1. prodromal fever with the 3 Cs (coryza, cough, conjunctivitis)
  2. koplik spots in mouth
  3. maculopapular rash that starts at head and spreads downward
18
Q

What disease is associated with Warthin Finkeldey cells?

A

measles

19
Q

What do all paramyxoviruses have in common?

A

surface F (fusion) protein which causes respiratory epithelium to fuse into multinucleated cells

20
Q

What do retroviruses cause?

A

HTLV and lentivirus