Exam 2 Review: Goldstein Flashcards

1
Q

5 non-pharmocological interventions for insomnia

A
  • exercise
  • decrease noise
  • dim the lights
  • decrease temp
  • reduce screens
  • reduce stim
  • reduce caffeine
  • reduce alcohol
  • reduce nicotine
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2
Q

what are 2 drugs from 2 different classes, used for both depression and insomnia

A
  • doxepin
  • trazodone
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3
Q

2 drugs for insomnia and anxiety

A
  • lorazepam
  • hydroxyzine
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4
Q

2 OTC medications for insomnia

A
  • benadryl
  • melatonin
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5
Q

3 drugs from 3 different classes for insomnia that are controlled substances

A
  • zolpidem
  • suvorexant
  • lorazepam
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6
Q

what is rebound insomnia

A
  • abruptly stopping insomnia medication/discontinuation of benzodiazepines

s/s: sleeplessness, worsening anxiety

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7
Q

first line treatment for depression and anxiety

A

SSRI
(selective serotonin reuptake inhibitors)

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8
Q

SSRI drugs

A
  • sertraline
  • fluoxetine
  • escitalopram
  • citalopram
  • paroxetine
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9
Q

name 3 PRN (as needed) drugs for anxiety

A
  • beta blockers
  • antihistamines
  • benzodiazepines
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10
Q

3 classes used for daily anxiety

A
  • SSRI
  • SNRI
  • TCA
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11
Q

name at least 3 different types of anxiety

A
  • generalized
  • social
  • OCD
  • PTSD
  • test anxiety
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12
Q

what is a drug class used for physical symptoms of anxiety

A

beta blockers

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13
Q

name at least 4 education points for a patient prescribed with SSRIs

A
  • do not stop Rx abruptly
  • you may experience weight gain
  • wait weeks for Rx benefits
  • may have increased appetite
  • women may experience sexual dysfunction
  • still need therapy when taking
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14
Q

SSRI help men with

A

premature ejaculation

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15
Q

some side effects of taking tricyclic antidepressants

A
  • ECG changes
  • CNS depression
  • orthostatic hypotension
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16
Q

what are some patient education points specific to phenelzine (hint: MAOI)

A

must be educated to avoid foods containing tyramine

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17
Q

what drug class inhibits the uptake of norepinephrine

A

MAOIs

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18
Q

2 primary neurotransmitters related to depression

A
  • serotonin
  • norepinephrine
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19
Q

2 screening tools for depression

A
  • PHQ2 (first step approach)
  • PHQ9 (further evaluation for PHQ2 positive results)
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20
Q

2 drug classes that do the same thing and works two different ways

A
  • SNRI
  • TCA
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21
Q

what 3 drugs can we use for the treatment of bipolar disorder

A
  • lithium
  • valproic acid
  • chlorpromazine
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22
Q

what lab values should we monitor for lithium?
what do we need to look out for?

A
  • lithium levels
  • thyroid
  • sodium level
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23
Q

name at least 4 second gen antipsychotics

A
  • aripiprazole
  • lurasidone
  • olanzapine
  • quetiapine
  • risperidone
  • ziprasidone
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24
Q

name 2 medications for antipsychosis first and second gen

A

1st gen: haloperidol
2nd gen: ziprasidone

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25
compare first gen and second gen antipsychotics (second gen advantage)
second gen has less side effects such as EPS (extrapyramidal sxs) and NMS (neuroleptic malignant syndrome)
26
what drug do we use to treat EPS?
benzitropine
27
what drug do we use to treat NMS
dantrolene
28
what are extrapyramidal sxs (EPS)
- dystonia - parkinsonism - akathisia - tardive dyskinesia
29
what are neuroleptic malignant syndrome (NMS) symptoms
- LIFE THREATENING - severe muscle rigidity - confusion - agitation - increased temperature, pulse and BP
30
what is the cause of serotonin syndrome
taking multiple serotonin medications - too much serotonin in CNS
31
what are SNRIs used for in addition to mental health disorders
- neuropathic pain - migraine prevention
32
what is the most common cause of schizophrenia medication to not work
medication compliance
33
how to help increase medication compliance
direct observation therapy (DOT)
34
what is the 1st line agent for ADHD
- methylphenidate or - amphetamine
35
what is the treatment of narcolepsy
modafinil (non-amphetamine stimulant)
36
what is the best choice treatment for ADHD with history of drug abuse
atomoxetine
37
effects of amphetamine and amoxitine
- weight loss - staying awake
38
BB warning for benzos
- high risk abuse - dependence
39
5 uses for benzodiazepines
- muscle relax - sedation - seizure - anxiety - insomnia
40
how long should pt expect to continue anti-depression medication
at least 6 months
41
which insomnia medication is considered safe to take long term
remeltione
42
what is the BB warning for olanzapine
not use for dementia related to psychosis
43
what is the BB warning for duloxitine
risk for suicide
44
name 2 drug classes that work by inhibiting bacterial cell wall synthesis
- penicillin - cephalosporin
45
what is an important patient education point for rifampin
it may change bodily fluids orange or red
46
name two cephalosporins
- cefazolin - ceftriaxone - cefepime
47
drug class antibiotics only used o resistant infection
oxazolidinones
48
what is pyrethrin used for
- scabies - lice
49
what are some patient education points for pyrethrin
scabies: - the entire body should be covered, excluding mucous membranes, and left covered for 8-4 hours lice: - wash hair, apply product and leave on for ten minutes, remove nits with nit comb
50
what drug class is pyrethrin
pediculossides
51
what are 2 drugs used for TB not not prophylactic
- pyrazinamide - ethambutol
52
how do vaccines work
dead pathogens or antigens are injected into the body - they do not cause disease - they do stimulate the production of memory cells - do not make you sick
53
name at least 5 diseases we have vaccinations against
- varicella - hep B - flu - covid - TB - HPV - HAV - pneumonia - tetanus - measles - mumps - etc.
54
common place for vaccine administration
IM (intramuscular)
55
what medication is used for severe fungal infection
amphotericin
56
what is interferon used for
severe viral infection (i.e. hep B virus, certain cancers)
57
interferon adverse effects
flu like symptoms
58
what is antibiotic resistance
- the more the antibiotic is used, the less effective it becomes - antibiotics kill harmful illnesses causing bacteria to the body - with frequent exposure however, bacteria can build up resistance to antibiotics - pathogen mutates and becomes resistant
59
what 2 pathogens are resistant to 2 specific antibiotics
- enterococci: resistant to vancomycin - staphylococcus aureus: penicillin
60
what principle combats antibacterial resistance? what is the global approach to address antibiotic resistance?
antimicrobial stewardship
61
what is antimicrobial stewardship
- match the drug to the bug - use narrow spectrum ABX when possible - educate patient to finish Rx - advocate for pt - ask if they need work or school note to prevent infection
62
name 5 pathogens
- bacteria - viruses - fungi - protozoans - parasites - helmetics
63
patient has mild allergic reaction to amoxicillin can we prescribe ampicillin
No
64
what pathogen would be killed off by re-administering tazobactam
none - beta lactam inhibitor does not kill off pathogen, does not treat disease
65
what would i be most concerned about with pt taking levofloxacin
tendinitis
66
what are 2 drugs from two different classes that are teratogenic
- aminoglycosides - vancomycin
67
3 drugs from 3 different classes that end in -mycin
- azithromycin - vancomycin - tobramycin
68
common drug class used as alternative for those allergic to penicillin
macrolides
69
what are 3 classes of antibiotics that are protein synthesis inhibitors
- macrolides - oxazolidinones - aminoglycosides
70
what is one patient education point for tetracyclines
take on empty stomach
71
what drug should you take with food
penicillin
72
2 drug classes (abx) that we learned, that are only IV
- carbapenems - aminoglycosides
73
3 drug classes that fall under antiretroviral pharmaceuticals
- NRTI - NNRTI - protease inhibitors
74
3 patient education points for someone undergoing antiretroviral therapy
- dont miss dose - stay on it for the rest of your life - take as prescribed - miss 1-2 doses then you will become resistant - get frequent testing for HIV RN and CO4 count
75
what 2 drugs are in augmentin
- amoxicillin - clavulanate
76
what 2 drugs are in descovy
- emtricitabine - tenofovir - alafenamide
77
what 2 drug classes are considered nephrotoxic
- amphotericin - aminoglycosides
78
what test would a provider most likely monitor with a patient taking isoniazid
- CMP (ALT, AST) - culture and sensitivity
79
most common concern with patient taking levofloxacin
- tendonitis - tendon rupture
80
common side effect with someone taking penicillin
upset stomach
81
name 4 drug/classes that are used prophylactically
- tenofovir - antimalarial - isoniazid - cipro
82
first line agent for pt with lower UTI
nitrofurantoin
83
what medication helps with the outbreak of shingles
acyclovir - must be taken 72 hours
84
what would you ask any patient prior to administration
do you have any allergies?
85
what is "ripe"?
4 drug cocktail for TB R: rifampin I: isoniazid P: pyrazinamide E: ethambutol