Exam 2 pulmonary part 2 Flashcards
Pathophysiology of Asthma
Intermittent and reversible airflow obstruction affecting airways only, not alveoli
Etiology of Asthma
- Inflammation:
Caused by cold air, dry air, specific allergens, general irritants, microorganisms, aspirin - Hyper-responsiveness:
caused by exercise, URI, GERD, unknown reasons
Asthma severity: Mild Intermittent- Class I
- Sx less than twice a week
Asthma severity: Mild Persistent- Class II
Sx more than twice a week, but not daily
Asthma severity: Moderate Persistent- Class III
Daily sx, with exacerbations twice a week
Asthma severity: Severe Persistent- Class IV
Sx occur continually with frequent exacerbations
Drug therapy for Asthma (Not the specific names): Preventive therapy (controller drugs)
- Change airway responsiveness to prevent asthma attacks
- Used every day, regardless of symptoms
Drug therapy for Asthma (Not the specific names): Rescue Drugs
Actually stop attack once it has started
Albuterol; Salmetrol
- Short- and long-acting beta2 agonists
- Bronchodilator
- Main rescue inhaler (Albuterol)
Ipratroprium bromide
- Cholinergic antagonists
- Bronchodilator
theophylline
- Methylxanthines
- Bronchodilator
Fluticasone, prednisone
- Corticosteroids
- Anti-inflammatory agents
nedocromil
- Cromones
- Anti-inflammatory agents
montelukast
- Leukotriene modifiers
- Anti-inflammatory agents
Status Asthmaticus
Severe, life-threatening, acute episode of airway obstruction
Intensifies once it begins, often does not respond to common therapy
Patient can develop pneumothorax and cardiac/respiratory arrest