Exam 2 Pulmonary Part 1 Flashcards
Steps of the Gas exchange process
Step 1: Ventilation
Step 2: Respiration
Step 3: Transport of Gases in the circulation
Ventilation definition/patho
The process of moving air between atmosphere & the lung alveoli and distributing air within the lungs to maintain appropriate concentrations of O2 and CO2 in the alveoli
Respiration definition/patho
The process by which alveolar air gases are moved across the alveolar-capillary membrane to the pulmonary capillary bed
Transport of Gases in the circulation definition/patho
Movement of oxygen and carbon dioxide to and from the tissue cells
Ventilation anatomy
-Lungs
(Lobes and mediastinum)
-Conducting airways
(Upper airways, Trachea, Bronchial tree)
- Gas exchange airways
(Bronchioles) and (Alveoli (Type I and II)
Ventilation/Perfusion (V/Q) normal ratio
0.8 (More pulmonary capillary perfusion than alveolar ventilation)
V/Q <0.8 means
- A decrease in ventilation in relation to perfusion has occurred.
- Similar to right to left shunt
- More deoxygenated blood is returning to the left heart
V/Q >0.8
- A decrease in perfusion in relation to ventilation
- pulmonary emboli, cardiogenic shock
Gas Transport mechanism
- Dissolved in Plasma
(PaO2 about 3%) - Bound to hemoglobin molecules
(SaO2=oxygen saturation about 97%)
The total always equals 100%
A “Shift to the Right” on the Oxyhemoglobin Dissociation Curve means what?
- Enhances oxygen delivery to the tissues
- Hgb has less affinity for oxygen
- Releases the O2 more Readily
“Think R in the words”
A “Shift to the RIght” on the Oxyhemoglobin Dissociation Curve etiology?
- Reduced pH (acidosis)
- hypeRcapneia (PCO2 increase)
- feveR
- IncRease levels of 2,3- diphosphglycerate (2,3-DPG)
“Think R in the words”
A “Shift to the Left” on the Oxyhemoglobin Dissociation Curve means what?
- O2 not dissociated from Hemoglobing (Hgb) until tissue and capillary O2 are very low, decreasing O2 delivery to the tissues
- Hemoglobin (HgB) has more affinity for oxygen
- Hemoglobing (HgB) hoLds the O2 to itself
“Think L in the words”
A “Shift to the Left” on the Oxyhemoglobin Dissociation Curve etiology?
- AlkaLosis (pH increase)
- Low CO2
- coLd
- Low levels of 2,3-DPG
- Increased Level of carbon monoxide poisoning
“Think L in the words”
Normal A-a Gradient?
Normal A-a gradient is 10-20 mm Hg, with the normal gradient increasing within this range as the patient ages
A-a Gradient specifics
- Provides an index on the efficiency the lung is in equilibrating pulmonary capillary O2 & alveolar O2
PaO2/FiO2 normal value
- Normal value is > 286
- Lower the number, the worse the lung function
Wide A-a gradient causes
- Lung is the site of the dysfunction
ventilation-perfusion mismatching, shunting, diffusion abnormalities
What is Capnometry and Capnography?
- Noninvasive
- Measure amount of carbon dioxide present in exhaled air
(Capnography is the sensing of exhaled CO2. Carbon dioxide is produced in the body as a by-product of metabolism and is eliminated by exhaling.) - By measuring exhaled CO2, many types of pulmonary assessments can be made.
What can cause the exhaled CO2 measured from the Capnometry and Capnography increase? Decrease?
Increase
- Think respiratory failure
- Increased work in breathing (trouble breathing)
Decrease
- Think perfusion, metabolic or psychological problem
- pulmonary embolism
- Diabetic ketoacidosis (DKA)
Endoscopy/bronchoscopy specifics
- Flexible or rigid
- Visualize, biopsy, aspirate material
- Sedation required
- NPO ~ 8 hrs prior
- Assess for return of cough & gag reflex before allowing pt to drink
- Complications
(Laryngospasm, pneumothorax, aspiration)
What is Thoracentesis
Aspiration of pleural fluid or air from pleural space
Thoracentesis procedure
- Stinging sensation and feeling of pressure
- Correct position (leaned over a table)
- Motionless patient
- Slow aspiration of fluid
(Limit to 1000 mL typically) - Follow-up assessment for complications
Thoracentesis complications
- Mediastinal shift
- Pneumothorax
- Bleeding
- Infection
- Subcutaneous emphysema
What is a lung biopsy
- Invasive
- Obtain tissue for histologic analysis, culture, cytologic examination
- May be performed in patient’s room
Lung biopsy follow-up care
- Assess vital signs, breath sounds at least every 4 hours for 24 hours
- Assess for respiratory distress
- Report reduced/absent breath sounds immediately
- Monitor for hemoptysis
Blood pH normal range
7.35-7.45
<7.35 is acidosis
>7.45 is alkalosis
blood PaCO2 normal range
35-45 mm Hg