Exam 2 Prep - ABX Flashcards
Which classes of antibiotics act by weakening the cell wall?
Penicillins
Cephalosporins
Carbapenems
Vancomycin
Which classes of antibiotics are bacteriostatic inhibitors of protein synthesis?
Tetracyclines
Macrolides
Clindamycin
Linezolid
Which classes of antibiotics are bactericidal inhibitors of protein synthesis?
Aminoglycosides
Which classes of drugs act by altering folate synthesis?
Sulfonamides
Trimethoprim
Narrow Spectrum Penicillinase-Sensitive Penicillins include:
Penicillin G
Penicillin V
Narrow Spectrum Penicillinase-resistant Penicillins include:
Nafcillin
Oxacillin
Dicloxacillin
Broad spectrum penicillins include:
Ampicillin
Amoxicillin
Extended-spectrum penicillins include _____ and are effective against _____
Piperacillin
Gram Negative (antipsuedamonal)
1st Generation Cephalosporins include:
Cephalexin (keflex)
Cefazolin (ancef)
Cefadroxil
Fifth generation cephalosporins include:
Ceftaroline
TETRACYCLINES
ACTION & DRUG LIST
PROTEIN SYNTHESIS
- Tetracycline
- Demeclocycline
- Doxycycline
- Minocycline
MACROLIDES
ACTION & DRUG LIST
Protein Synthesis
- Erythromycin
- Azithromycin
- Clarithromycin
CLINDAMYCIN
ACTION & NUGGETS
Bacteriostatic Protein Synthesis
- Causes CDiff
- Hepatotoxic
- Doesn’t cross BBB
LINEZOLID
ACTION & NUGGETS
bacteriostatic protein synthesis
- VRE/MRSA
- DO NOT TAKE WITH MAOIS OR SSRIS
AMINOGLYCOSIDES
ACTION & DRUG LIST
Bactericidal Protein Synthesis
- Gentamycin
- Amikacin
- Tobramycin
- Neomycin
BACTRIM
MOA & NUGGETS
Folic Acid Synthesis Inhibitor
- Sulamethoxazole & Trimethoprim
- Lots of drug interactions (Warfarin and Dilantin)
- Megaloblastic anemia (folate deficiency)
FLOUROQUINOLONES
ACTION & DRUG LIST
Disrupts DNA and RNA synthesis
- Ciprofloxacin
- Ofloxacin
- Levofloxacin
- Metronidazole
Which cephalosporins cause alcohol intolerance?
Cefotetan and Cefazolin
Which cephalosporins can cause bleeding tendencies?
Cefotetan and Ceftriaxone
Each generation of cephalosporins becomes increasingly ______
- Active against gram (-)
- resistance to beta lactamases
- able to reach the CSF
Which generation of cephalosporins are the preferred treatment for meningitis?
Third (Ceftriaxone/Rocephin)
Which carbapenem is active against MRSA?
None of them
Which antibiotic interacts with Valproate?
Imipenem
Which class of antibiotics tends to cause seizures?
Carbapenems
Think: Kind of sounds like carbamazepine
