Exam 2 Pharmaceutical Calculations Flashcards
Dosages of drugs and drug regimens are often based on _______.
patient-specific parameters
Examples of patient-specific parameters
Body surface area (BSA)
- *Weight
- *creatinine clearance (Clcr)
patient-specific parameter that is not commonly used
Body Surface Area (BSA)
Two methods clinicians generally use for Body Surface Area (BSA)
Formula and Nomogram
actual body weight
what you weigh
ideal body weight
what you should weigh
I inch is how many cm?
2.54 cm
1 pint is how many fluid ounces?
16 fluid ounces
1 pint is how many mL?
473-480 mL
I tsp is how many mL?
5 mL
1 tbsp is how many mL?
15 mL
1 kg is how many pounds?
2.2 lb
I ounce is how many grams?
28.4 - 30 grams
1 fluid ounce is how many mL?
30 mL
Females: IBW formula
45.5 kg + 2.3 kg for each inch over 5 ft
Males: IBW formula
50 kg + 2.3 kg for each inch over 5 ft
% Ideal Body Weight formula
actual weight/IBW x 100
adjusted body weight formula
IBW + 0.4 (ABW-IBW)
male creatine clearance formula
(140-age)x kg / SrCr x72
female creatine clearance formula
(140-age)x kg / SrCr x72 times the whole things by .85
creatine is breakdown product of ____.
muscle
what can influence creatine
disease
lifestyle
you give pt antibiotics, his creatine clearance is 44 today and two days ago it was 77. what should you do?
lower strength of drug, decrease frequency
3 ways we measure concentration
W/W
W/V
V/V