Exam 2 - Membrane Transport Flashcards
What are the two types of diffusion?
- Passive, protein independent, non-mediated
- Passive, protein dependent, mediated or non-mediated
What types of proteins allow for passive, non-mediated membrane transport?
Channels
What are the two types of passive, protein dependent transports?
Channels
Carrier Proteins
Channel Proteins
- Transport is []
- Channel proteins are [] for size/shape
- Typically involved in transporting [] ions like […]
- Flow is [] or gated - meaning they open and close in response to a []
- bidirectional
- selective
- inorganic ions, K, Mg, Na, NH4
- regulated….stimuli
What are the 4 steps of a Facilitated Diffusion Transporter?
- Recognition
- Transport
- Release
- Recovery
Does active transport depend on a concentration gradient?
Negative
What are the 4 sources of energy for active transport?
- ATP
- Electrochemical Gradient - like in Na/K pumps
- Redox Energy
- Light
What super secondary structure are channels made?
What super secondary structure are porins made of?
- Channel - alpha-helical domain folded into barrel
- Porin - Beta-sheets fold on itself
What are the characteristics of a porin?
Where are they found?
- Allows for bigger molecules to pass through, not regulated, not selective, formed by beta-sheets
- Outermembrane of mitochondria/chloroplasts and bacteria.
What type of protein is an Aquaporin?
a water channel
What Glut transporter(s) are always operating at Vmax?
Glut 1, 3, 4
What Glut transporter(s) respond to changes in the blood glucose levels?
Glut 2
What tissues do you find the GLUT 1 transporter?
RBC
Heart
What tissues do you find the GLUT 2 transporter?
Liver
What tissues do you find the GLUT 3 transporter?
Brain
