Exam 2- liver functions Flashcards
functions of liver
metabolism/storage of fat, carbs, protein, vitamins/minerals,
blood volume reservoir
purifies blood
create blood clotting factors
cells of the liver
lobules = functional units
hepatocytes = liver cell that can regrow
kupffer cells = remove toxins
portal circulation leads to what
first pass effect
LFTs (liver function tests)
ALT (inc)
AST
Alk phos
bilirubin (inc)
ammonia (inc)
PTT (inc)
protien (dec)
albumin (dec)
jaundice is caused by
inc bilirubin in bloodstream
types of jaundice
hemolytic - breakdown of RBCs
hepatocellular- liver unable to take up bilirubin
obstructive- obstructive bile flow
bilirubin is what
breakdown of heme (hemoglobin)
direct bilirubin
AKA conjugated
liver is working but obstruction
indirect bilirubin
AKA unconjugated
bilirubin is overproduced or impaired liver
more common