Exam 2- benign prostatic hyperplasia

Question 1

what is BPH

Answer 1

nonmalignant (noncancerous) enlargement of prostate epithelial cells and smooth muscle

Question 2

epithelial cells cause what in BPH

Answer 2

mechanical obstruction

Question 3

smooth muscle enlargement in BPH causes what

Answer 3

dynamic obstruction

Question 4

RF for BPH

Answer 4

age
history
race
UTIs

Question 5

causes of BPH (2)

Answer 5

1. hormone imbalance
2. DHT accumulation

Question 6

DHT activates what

Answer 6

growth factors

Question 7

S/S of BPH

Answer 7

frequency
urgency
dribblingc

Question 8

complications of BPH

Answer 8

obstruction –> stones
UTI
renal problems

Question 9

2 drug classes for BPH

Answer 9

1. 5-alpha reductase inhibitor
2. alpha1- adrenergic antagonist

Question 10

Finasteride class

Answer 10

5-alpha reductase inhibitor

Question 11

Finasteride indication

Answer 11

mechanical obstruction of urethra, only works with enlarged prostate

Question 12

finasteride moa

Answer 12

blocks testosterone –> DHT conversion (dec. epithelial tissue in prostate)

Question 13

finasteride nursing considersations

Answer 13

takes 6-12M to work

Question 14

finasteride SE

Answer 14

dec libido, gynceomasia

Question 15

Dutasteride class

Answer 15

5-alpha reductase inhibitor

Question 16

Dutasteride indication

Answer 16

same as finasteride (mechanical obstuction)

Question 17

tamsulosin class

Answer 17

alpha-1 adrenergic antagonist

Question 18

tamsulosin indication

Answer 18

dynamic obstruction

Question 19

tamsulosin moa

Answer 19

selectively relaxes smooth muscles in prostate