Exam 2 Extra Flashcards
Both helper and killer T cells require activation before the can function. T/F
True
If the T cells sees non-self, but doesn’t get co-stimulated it will be rendered inactive. What word is used for this process?
Anergized
Once the helper T cell is activated by MHC 2, what cytokines does it secrete?
IL-2 & IFN-Y
What two processes must a T cell go through to become activated?
TCR recognizes cognate antigen on MHC plus co-stimulation
Will T cells recognize soluble molecules?
No! T cells only recognize peptides presented by MHC I or MHC II molecules
What are the two types of traditional TCR’s?
αβ (95%)
What are the two non-traditional TCR’s?
γ, δ
Non-traditional TCR’s are most abundant in what part of the body?
Uterus, tongue, & intestine.
One helper T scans _______ dendritic cells per hour
1000 dendritic cells per hour.
What is the time frame for complete activation of a T helper cell.
4 - 10 hours.
Which cytokines recharges NK cells
IL-2
Which growth factor is used to proliferate T cells (releasing Th2 cytokines)?
IL-4
Which growth factor is used for B cells that are making IgE?
IL-4
Which IL causes B cells to make IgA (antibacterial in the GI)?
IL-5
Which IL stimulates mucus in the intestine?
IL-13
Our intestines are home to____________ bacteria of at least _______different types
~ 1.0 x 1014, 1000
Intestinal surface area is ________?
~ 200 M2
