Exam 2, Anticoagulant drug CIS, martin Flashcards
What is PT
prothrombin time for extrinsic pathway
What is INR for warfarin therapy
2-3
what is aPTT
activated thromboplastin time
Are DVTs red clots or white clots
red
What tests shoul dbe performed before DVT Tx
Hct, PT, aPTT, platelet count and stool sample for occult blood
why do you use heparin to help with a DVT
because thrombolytic could lead to serious bleeding
With a DVT, how would you administer heparin
loading dose to get levels up fast then constant rate
with active pulm embolism what therapy is immediately started
heparin therapy for 5 days
warfarin inditiated day 1 and continued 3-6 months
What does INR stand for
international normalization ratio
With patient in A fib what threapy should you initiate? and for how long until cardioversion procedure
anticoagluant because risk of embolism from A fib is very high
low intesnsity warfarin theraphy to an INR 2-3
3 weeks prior to cardioversion
What is the antiplatelet agent of choice in patients with vascular disease of any origin
aspirin
what drug acts by being an agonist for peroxisome proliferator-activated receptor alpha
fibrate
what genetic changes incholesterol pathway are expected with statin therapy
increased expression LDL R because overall decrease of cholesterol intracellularly
how do statins work on VLDL
decrease expression
after taking a stain for one week paitent complains of leg and arm pain, what could acount for this
increased creatine kinase
