Exam 2 Flashcards
histology
study of tissue
4 major tissue types
epithelial
connective
muscle
nervous
extracellular matrix
synthesized and secreted by cells of the tissue
proteoglycans
insolvable protein fibers (collagen)
epithelial tissue
line any free surface any substance that enters or leaves the body must cross it cellular little matrix avascular leaky and tight
simple squamous
a single layer of flattened cells
blood vessels and heart
allows materials to pass via diffusion and filtration
simple cuboidal
a single layer of cube-shaped cells
kidney tubules, glands, ducts, thyroid
secretion and absorption
simple columnar
a single layer of column cells lines GI tract microvilli goblet cells absorption and secretion of mucus, enzymes, etc
pseudostratified ciliated columnar
cilia and goblet cells secrete substances (mucus) and propels mucus
stratified squamous non keratinized
several layers of flattened cells
alive
protect underlying tissues in vulnerable areas
mouth, esophagus, vagina, anus
stratified squamous keratinized
several layers of flattened cells
dead
waterproof keratin
epidermis
transitional epithelium
flattened or cuboidal
allows stretching without rupturing
bladder, uterus, urethra
stratified cuboidal
several layers of cube-shaped cells
protect duct areas of sweat, salivary, and mammary glands
goblet cell
secrete mucus
exocrine glands
release secretions to the outside environment via ducts
sweat, mammary, salivary glands
serous, mucus, mixed
endocrine
ductless glands that release hormones to the intracellular fluid
pancreas, thyroid, gonads, pituitary
characteristics of connective tissue
lots of extracellular matrix with scattered cells
collagen, elastin, or reticular fibers
-blast
a cell that is growing or secreting matrix
-clast
a cell is actively breaking down matrix
-cyte
a cell that is not actively making or destroying the matrix
collagen
most abundant protein
flexible but inelastic
elastin
allows stretching and recoils
reticular
thin, short branching collagen fibers
areolar connective tissue
lots of matrix with all 3 fiber types
contain fibroblasts, macrophages, mast cells, WBCs
forms lamina propria, packages organs, surrounds capillaries
adipose tissue
little matrix
highly vascular
triglyceride storage, insulation, supports and protects organs
reticular connective tissue
a network of reticular fibers in a loose ground substance forms stroma for soft organs lymph nodes, spleen, red bone marrow forms the internal soft skeleton lots of nuclei
dense regular connective tissue
parallel bundles of collagen with little ground substance
resists pulling forces along the length of fiber
ligaments and tendons
attach muscle to bone or bone to bone
dense irregular connective tissue
fibers run in all directions
resists pulling in multiple directions
the dermis of the skin, joint capsules
provide structural strength and support
characteristics of cartilage
chondrocytes in lacunae with lots of matrix
avascular and lacks nerve fibers
hyaline cartilage
most abundant
support, reduces friction and compression forces
ends of long bones, costal cartilages, nose, trachea, and larynx
elastic cartilage
more elastic fibers
allows flexibility while maintaining the shape
the external ear, epiglottis
fibrocartilage
lots of collagen
strong shock absorber
pubic symphysis, intervertebral discs, the meniscus of the knee
bone connective tissue
hard calcified matrix with osteocytes sitting in a lacunae
organic: collagen
inorganic: hydroxyapatite
functions of bone
support and protection
site of muscle attachment
stores minerals (Ca+2) and fat
red and yellow bone marrow
blood connective tissue
red and white blood cells in a fluid matrix (plasma)
transports respiratory gases, nutrients, waste, hormone
skeletal muscle tissue
attach to the skeleton, generate movement and heat
striated
multinucleate
voluntary
cardiac muscle tissue
heart, propels blood thru body striated branched uninucleate intercalated discs involuntary
smooth muscle tissue
walls of hollow organs fusiform uninucleate lacks striations involuntary
nervous tissue
brain, spinal cord, nerves
transmit electrical impulses
neurons and glial cells (supporting cells)
characteristics of skin
covers body
stratified squamous keratinized
avascular
keratinocytes
most numerous cell in the skin
produce waterproof keratin
melanocytes
spider-shaped cells that produce a pigment called melanin
the deepest layer of the epidermis
surrounds nuclei to protect from UV
Langerhans cells (dendritic cells)
function in the immune system
Merkel cells
sensory receptor for touch
stratum corneum
20-30 layers of dead cells, the top layer
protect the body from mechanical and chemical stress
inhibit dehydration
cells flake off
stratum lucidum
only thick skin
appears clear
2-3 layers of clear, flat, dead keratinocytes
in palms and soles of feet
stratum granulosum
3-5 layers of flattened cells
organelles begin to disintegrate
cytoplasm full of granules, keratinization taking place
stratum spinosum
several layers of keratinocytes linked by desmosomes
contains dendritic cells
dermis
layer deep to the epidermis
blood vessels, nerve fibers, lymphatic vessels, and appendages
the papillary and reticular layer
a papillary layer of the dermis
superficial areolar CT dermal papillae (projections) blood vessels and Meisner's corpuscles fingerprints create friction
reticular layer of the dermis
deep (80% of the dermis)
dense irregular CT
tension lines
run lengthwise along with appendages and horizontal along the trunk
cuts made parallel to lines cause less scaring
stretch marks
striae
dermal tears
blister
separation of dermis and epidermis
hypodermis
adipose tissue deep to the dermis
cushions, insulates, gives the body shape
melanin
pigment
all races have the same number of melanocytes
UV exposure increases the amount of melanin produced
genetics
freckles and moles are accumulations of melanin
eccrine sweat glands
most numerous, empty secretion through a pore
pals, soles of feet and forehead
sweat
water, NaCl, vitamin C, antibodies, H+, and metabolic wastes function in thermoregulation