exam 2 Flashcards
epidermis
stratified squamous kertanized ET
dermis
denser irregular CT
layers of skin
basale spinosum granulosum lucidum corneum
stratum basale
simple cubiodal & columnar
connects epidermis to dermis
three cells in basale layer
keratinocytes
melanocytes
tactile cells
keratinocytes
most abundant
in all layers
produce keratin
keratin
makes skin water resistant
melanocytes
produce and store melanin
shield dna from uv radiation
skin tone
tactile cells
merkel cells
only in basale
touch
stratum spinosum
spiny
desomsomes
langerhans cells
spinosum and granulosum
immune response
response to pathogens and cancer cells
stratum granulosum
keratinization begins
keratinocytes fill with keratin
cells start to die
stratum lucidum
only im thick skin
protects against uv light
startum corneum
top layer
dead cells
shed
thick skin
palms and soles
all 5 layers
sweat glands
no hair or oil glands
thin skin
lacks lucidum
sweat, hair, and oil
hemoglobin
oxygen binding protein in RBCs
gives blood vessels red tint
melanin
melanocytes
depends on heridity and light exposure
all have same number
dark skins have dark melanin
dermis
connective tissue
collagen, elastic, reticular fibers
immune function
blood, sweat, oil, hair, nail, sensory, arrector pilli msucles
layers of dermis
papillary and deeper reticular layer
papillary lauer
top
aerolar CT
dermal papillae - ridges
reticular layer
major part of dermis
dense irregular CT
collagen fiber bundles
stretch marks
collagen and elastic fibers
resist stress
lines of cleavage
tension lines
surgrey
collagen fibers
strength
elastic fibers
stretch and recoil
subcutaneous tissue
areolar and adipose CT
pads and protects body
energy reservoir
thermal insulation
funktion of skin
protection
physical barrier
prevents water loss or gain
vitamen D production
vitamen D
synthesized from keratinocytes
upon uv exposure
stored in kidneys
increase absorption of calcium and phosphaye
temperature regulation
capillaries and sweat glands in dermis
vasoconstriction
vessels narrow
heat is lost
occurs when trying to comserve heat
vasodilation
vessels increase
results in pink skin tone
sensory reception
nerve fibers
monitor stimuli
sent to brain
nails
modified stratum corneum
protects tips of fingers
aids in graspin
hair
almost everywhere
keratinized cells
lanugo
fin
unpigmented
downy hair
vellus
fine hair
primary
upper and lower limbs
terminal
coarser
pigments
longer
scalp, eyebrows, pubic regions
hair bulb
hair orginates im dermis
surround hair papilla
living cells
root
area of hair from bulb to skin surface
shaft
hair beyond surface
hair follicle
into defmis amd subcutaneous layer
arrector pilli muscles
smooth muscle
goosebumps
function of hair
protects scalp from sunburn and injury
hair in nostrils traps particles
hair im ear protects from foreign matter
protects eyes
types of exocrine glands
sweat and sebacous
sweat glands
merocrine
apocrine
merocrine sweat glands
most numerous
discharge onto skin
secreat sweat
thermoregulation
apocrine sweat glands
discharge secretions into hair follicles
carbon based secretions
produce ordor
sebaceous glands
produce sebum (oil) lubricates skin and hair
ceruminois glands
modified apocrine sweat glands
only in external ear canal
secrete waterproof cerumen
traps foreign materieal
components of skeletal system
bones cartilage tendons ligaments CT
bones
rigid framework of body
types of bones
compact
spongy
compact bone
dense
dense CT
solid
80% of bome mass
spongy bone
cancellous or trabecular bone
under compact bone
appears porous
20% of bone mass
bones serve as attachment sites for
skeletal muslces
soft tissues
some organs
hemopoiesis
blood cell production
in red bone marrow CT
stem cells form blood cells and plateltes
bones stores
calcium and phosphate
released into blood as needed
lipids stored in yellow bone marrow
long bones
more longer than wide
have a diaphysis
most common
limbs
short bones
length equals width
carpal, tarsals, sesmoid, patella
flat bones
flat surfaces, slightly curved
muscle attachment
protect underlying tissues
roof of skull, scapulae, sternum, ribs
irregular bones
complex shapes
vertebrae
diaphysis
elongated cylindrical shaft
compact bone
medullary marrow cavity
hollow space inside diaphysis
conatins red bone marrow then yellow bome marrow in adults
epiphysis
ends of long bones
thin layer of compact bone
epiphyseal playe
thin hyaline cartilage
growth in length
becomes epiphyseal line
articular cartilage
thin hylime cartilahe at joints
reduces friction
shock absorber
periodteum
covers outer surface of bones
dense irregualr CT
anchors blood vessels and nerves
attachment for ligaments and tendons
inner layer
has bone cells
attached via collagen fibers
endosteum
lines medullary cavity
incomplete layer of cells
flat bone compostion
two layers of compact bone with spongy bone in between
bones are higly
vascularized
vessels enter from periodteum
nerves that supply bone
accompany blood vessels through foramen
mainly sensory nerves
bone marrow
soft CT of bone
red and yellow
red bone marrow
hemopoietic
retcular CT
kids: spongy bone and medullary cavity
adults: selected areas of axial skeleton
yellow bone marrow
product of red bone marrow degeneration
fatty substance
can convert back to red bone marrow
osteopeogenitor cells
derived from mesenchyme
matures to become osteoblast
located in periosteum and endosteum
osteblasts
side by side on bone surface
synthesize and secrete osteoid
osteod calcifies in matrix
differentiate into osteocytes
osteocytes
long bone forming abilitie
maintian bone matrix
detects stress
triggers creation of new bone matrix
osteoclasts
phagocytic cells
derived from fused bone marrow cells
involved in resorption
osteoid contains
collagen
ground substance
gives strenth by resisting stretch
bone flexibility
inorganic components of bone
salts crystals= calcium phosphate
hardens around collagen fibers which makes bones rigid
bone formation
secretion of osteoid
calcification occurs
bone resorption
bone production requres
vitamen d for calcium absorption
vitamen c for collagen formation
calcium and phosphate for calcification
bone resorpfoon
bone matrix destroyed
enzymes digest organic components
calcium and phosophate dissolve
extra calcium enters blood
compact bones have
osteons
perforating canals
volkmann canals
central canals
blood vessles amd nerves
perpendicular to centeal canal
conmects centeal canal with other osteons
circumferential lamellae
rings of bone
entire circumference
imtersititial lamella
between osteons
incomplete without central canal
trabeculae
open lattice of narrow rods and plates of bones
bone marrow fills spaces
stress resistant
parallel lamellae
bone matrix
osteocytes between lamellae
canaliculi radiate from lacunae
ossification
formation and development of bone CT
begins in embryo
intramembranous ossification
bone growth within membrane
produced flat bones of skull and mandible
stemls of intramembraneou ossification
thickened regions of mesenchyme
cells become osteoprogenitor cells
others are osteoblasts
ostoid undergoes calcification
woven bone amd surround periosteum form
lamellar bone replaces woven bine
bones form trabeculae
layers of compact and spongy
endochondral ossification
hyaline cartilage model
cartilage calficies and perioste bone collar forms
makes holes in matrix
blood vessels grow osteoblasts that secrete osteoid
forms diaphysis
capillaries and osteoblasts form
epiphyses form
bone replaces cartilage
creates medullary cavity
bone replace cartilage except epiphyseal plate
bone continues to grow until puberty