Exam 1 Questions Flashcards
What are the two components that make up blood?
Plasma and Formed elements
What three things make up formed elements?
Erythrocytes, Luekocytes and Platelets
WHat two things make up Plasma?
H2O and solutes
WHat percent of plasma is water
90
What percent of plasma is protein
8
What does Albumin do in plasma?
main contributor to osmolarity
What two things make up Globulins?
Alpha/Beta and gamma
What does alpha/ beta cells do in plamsa?
They are the carrier proteins
WHat does Fibrinogen do in Plasma?
Forms fibers during blood clotting?
What is the buffy coat between plasma and blood made up of?
Leukocytes and platelets
What percent of blood is erythrocytes?
45%
WhaT are erythrocytes filled with?
Hemoglobin
WHat does Hemoglobin consisit of?
globin and 4 heme groups
Plasma makes up what percent of blood
55
In order of density from least to most rank plasma,, eryrheocytes and buffy coat
plasma, buffy coat, erythrocytes
What is the function of leukocytes?
DEFENSE
What are the two types of leukocytes
granular and agranular
What do neutrophils attack?
bacteria
What do eosinophil attack?
Parasites
What do Basophils release?
Histamine
Which cells of the lymphocyte attack virus infected cells?
T Cells
What is another name for platelets?
Thrombocytes
Platelets are technically…
cell fragments
Platelets or thrombocytes function is
blood clot formation
WHat happens in the Capillary beds of lungs and tissue?
Gas exchange happens
What is stenosis?
when the valve gets stiff and doesn’t open as easily or as wide
What is a heart murmur?
Sound generated by blood rushing past on object (such as stenotic valve or leaky valve)
What do coronary arteries do?
Provide blood supply to myocardium
If a coronary artery is blocked what happens?
Heart attack
What is a systole?
Contraction
What is end systolic volume
volume when fully contracted
What is diastole
relaxation and expansion
What is stroke volume
the amount of blood pumped by a ventricle per beat
WHat are the 2 main cell types
pacemaker cells and cardiac myocytes
What do pacemaker cells do
control heart rate
what do cardiac myocytes do
its ability to contract
What is angioplasty
a procedure to open narrowed or blocked arties caused by deposits of plaque
What are the 3 types of vessels?
artery, capillary, veins
Rank the 3 vessels from thinniest to thickest walls
capillary. vein and thinner
Which vessel has the location of gas and nutrient exchange
capillary
Of the plasma components the main contribution to osmotic pressure is….
Albumin
What are the two storage molecules for iron
Ferritin
Hemosiderin
What is the molecule that carries iron through blood?
Transferrin
What is ferritin
Big storage area of iron
What is transferrin
Protein that transfers iron
Having ______ copy of HbS gene will cause sickle cell trait and confer malarial resistance
One
WBCs can exit blood vessels via ________, an ameboid motion permitting positive chemotaxis
Diapedesis
What does the T cell do
Attack virus infected cells
What does the B cell do
Make antibodies
Which cell type turns into macrophages that engulf various pathogens
Monocytes
What are the two sub groups of lymphocytes
T cells
B cells
If B cells are activated the turn into _____ which secret antibodies
Plasma cells
List the granule yetis
Neutrophil
Eosinophils
Basophils
List the agranulocytes
Lymphocytes
Monocytes
Which WBCs are derived from myeloid stem cells
Granular and agranular leukocytes except lymphocytes
Which granulocytes takes up red dye
Eosinophils
Which granulocytes takes up blue dye
Basophils
Valves are one way doors that are opened and closed by?
Positive and negative pressure generated by the heart
AV valves open when atrial pressure is____ than ventricular pressure
Greater
AV valves close when atrial pressure is _____ than ventricular pressure
Less than
Which phase of membrane potential is first
Depolarization
Which phase of membrane potential is second
Plateau
Which phase of membrane potential is he last
Repolarization
Which phase of membrane potential is effected by Na
Depolarization
Which phase of membrane potential is effected by K
Repolarization
Which phase of membrane potential is effected by Ca
Plateau phase
List the four chambers of the heart in order of blood flow beginning with deoxygenated blood coming into the body
Right atrium
Right ventricle
Left atrium
Left ventricle
List the four valves blood passes through in order
Tricuspid valve
Pulmonary valve
Bicuspid valve
Aortic valve
What molecular structure in sarcolemma makes the cells electrically coupled
Gap junctions
This slow depolarization is due to the opening of Na channels
Pacemaker potential
Ecg components what is happening at the letter P
Atrial depolarization
Ecg components what is happening between P and Q
Impulse is delayed at AV node
Ecg components what is happening at the letter Q R S
Ventricular depolarization at apex
Ecg components what is happening between S T
Depolarization complete
Ecg components what is happening at the letter T
Ventricular repolarization begins at apex
Ecg components what is happening after the letter T
Ventricular repolarization
What decreases depolarization speed in pacemaker cells by opening K channels
Acetylcholine
What increases depolarization speed in pacemaker cells by increasing caption influx into the heart
Epinephrine/ norepinephrine
Which capillary is least permeable
Continuous
Which capillary is the most permeable
Sinusoid
Which capillary occurs in areas of active absorption or flirtation like kidney or small intestine
Fenestrated capillary
Which capillary occurs in skin and muscle
Continuous capillary
Which capillary occurs in special locations like liver bone marrow spleen
Sinusoid
Which type of vessel is solely endothelium
Capillary
Name two parts of vascular shunt
Metarteriole
Thoroughfare channel
Which vessel has the smallest diameter
Capillary
Does Vasodilation or Vasoconstriction increase pressure?
Vasoconstriction
Which area has the lowest blood pressure
Venae cavae
Which area has the highest blood pressure
Aorta
What three things regulate blood pressure
Neural
Hormonal
Renal
Which hormones increase blood pressure
norepinephrine/epinephrine
angiotensin
antidiuretic hormone
aldosterone
What stimulates thrist perception in the brain
angiotensin
What hormone promotes water retention
Antidiuretic hormone
What hormone promotes Na retention
Aldosterone
What stimulates vasodilation and Na excretion in urine
atrial natriuretic peptide
what is hypertension
high blood pressure
What is atheroslerosis
build up of plaque
What blocks angiotensin pathway
ACE inhibitors