Exam 1: Lecture 2 Flashcards

mitosis and meiosis

1
Q

gene

A

distinct seq of nucleotides forming part of a chromosome; unit of heredity that is transferred from parent to offspring

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2
Q

allele

A

one of two/more alternative forms of a gene that arise by mutation and are found at the same place on a chromosome

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3
Q

chromosome

A

threadlike structure of nucleic acids and protein found in the nucleus of most living cells, carries genetic info in the form of genes

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4
Q

genome

A

complete set of DNA, including all of its genes

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5
Q

germplasm theory

A

inheritance in a multicellular organism only takes place by means of the germ cells ONLY

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6
Q

characteristics of a prokaryote

A
  • circular DNA (protects ends from nucleases and small amt)
  • single cell
  • nucleus absent
  • no mem bound organelles!
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7
Q

characteristics of eukaryotes (uni and multicellular)

A
  • membrane bound organelles! i.e. mito!!
  • chromosomes composed on DNA (multiple linear DNA molecules and lrg amt)
  • proteins (histones) and functional units
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8
Q

prok DNA arrangement? who is considered a prok?

A

disordered DNA and made up of eubacteria and archaea

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9
Q

what are viruses

A

DNA/RNA stored inside a protein coat; has enough info to hijack another cell

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10
Q

what is a homologous chromosome?

A

2 copies of a chromosome, not identical; each homolog carries the same genes in the same order, bu alleles for each trait may be diff

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11
Q

diploid cells

A

carry two sets of genetic info

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12
Q

haploid cells

A

carry one set of genetic info

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13
Q

centromere

A

attachment point for spindle microtubules; kinetochores form and the spindle microtubules attach (tubulin)

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14
Q

telomere

A

tips of a linear chromosome; stable ends of chromosomes

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15
Q

submetacentric

A

short arms

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16
Q

metacentric

A

centromere in the middle

17
Q

telocentric

A

almost no short arm; no genes

18
Q

acrocentric

A

centromere near the end producing a short arm ex chromosome 21 and 22

19
Q

interphase

A

extended period between cell divisions, DNA synthesis, and chromosome replication stage

G1, S, G2; G1/S and G2/M checkpoints

20
Q

mitosis

A

separation of sister chromatids; PMAT

21
Q

cytokinesis

A

separation of cytoplasm

22
Q

the number of chromosomes per cell =

A

the number of functional centromeres

23
Q

meiosis

A

production of haploid gametes

24
Q

fertilization

A

fusion of haploid gametes

25
genetic variation
conseq of meiosis
26
meiosis I
Meiosis I is separation of homologous chromosome pairs, and reduction of the chromosome number by half
27
meiosis II
Meiosis II is separation of sister chromatids, aka equational division
28
microtubules lengthen and shorten at
both the pos and neg ends
29
homologous chromosomes
similar but not identical; each homolog carries the same genes in the same order, but the alleles for each trait may not be the same
30
chromatid
either of 2 daughter strands of a duplicated chromosome; separate during cell division to become individual chromosomes
31
prophase I of meiosis I: what occurs during this phase?
synapsis tetrad crossing over
32
synapsis
prophase I; close pairing of homologous chromosomes
33
tetrad
prophase I; closely associated four-sister chromosomes of 2 homologous chromosomes
34
crossing over:
prophase I; exchange of genetic info, the first mechanism that generates genetic variation in newly formed gametes
35
metaphase I
random alignment of homologous pairs of chromosomes along the metaphase plate
36
anaphase I:
separation of homologous pairs and random distribution; second mechanism of generating genetic variation in newly formed gametes
37
telophase I
cytoplasm divides and chromosomes at opp poles
38
interkinesis
spindle breaks down, chromosomes relax, and nuclear envelope re-forms; no DNA synthesis