Exam 1: Lecture 2 Flashcards

mitosis and meiosis

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1
Q

gene

A

distinct seq of nucleotides forming part of a chromosome; unit of heredity that is transferred from parent to offspring

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2
Q

allele

A

one of two/more alternative forms of a gene that arise by mutation and are found at the same place on a chromosome

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3
Q

chromosome

A

threadlike structure of nucleic acids and protein found in the nucleus of most living cells, carries genetic info in the form of genes

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4
Q

genome

A

complete set of DNA, including all of its genes

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5
Q

germplasm theory

A

inheritance in a multicellular organism only takes place by means of the germ cells ONLY

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6
Q

characteristics of a prokaryote

A
  • circular DNA (protects ends from nucleases and small amt)
  • single cell
  • nucleus absent
  • no mem bound organelles!
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7
Q

characteristics of eukaryotes (uni and multicellular)

A
  • membrane bound organelles! i.e. mito!!
  • chromosomes composed on DNA (multiple linear DNA molecules and lrg amt)
  • proteins (histones) and functional units
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8
Q

prok DNA arrangement? who is considered a prok?

A

disordered DNA and made up of eubacteria and archaea

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9
Q

what are viruses

A

DNA/RNA stored inside a protein coat; has enough info to hijack another cell

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10
Q

what is a homologous chromosome?

A

2 copies of a chromosome, not identical; each homolog carries the same genes in the same order, bu alleles for each trait may be diff

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11
Q

diploid cells

A

carry two sets of genetic info

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12
Q

haploid cells

A

carry one set of genetic info

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13
Q

centromere

A

attachment point for spindle microtubules; kinetochores form and the spindle microtubules attach (tubulin)

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14
Q

telomere

A

tips of a linear chromosome; stable ends of chromosomes

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15
Q

submetacentric

A

short arms

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16
Q

metacentric

A

centromere in the middle

17
Q

telocentric

A

almost no short arm; no genes

18
Q

acrocentric

A

centromere near the end producing a short arm ex chromosome 21 and 22

19
Q

interphase

A

extended period between cell divisions, DNA synthesis, and chromosome replication stage

G1, S, G2; G1/S and G2/M checkpoints

20
Q

mitosis

A

separation of sister chromatids; PMAT

21
Q

cytokinesis

A

separation of cytoplasm

22
Q

the number of chromosomes per cell =

A

the number of functional centromeres

23
Q

meiosis

A

production of haploid gametes

24
Q

fertilization

A

fusion of haploid gametes

25
Q

genetic variation

A

conseq of meiosis

26
Q

meiosis I

A

Meiosis I is separation of homologous chromosome pairs, and reduction of the chromosome number by half

27
Q

meiosis II

A

Meiosis II is separation of sister chromatids, aka equational division

28
Q

microtubules lengthen and shorten at

A

both the pos and neg ends

29
Q

homologous chromosomes

A

similar but not identical; each homolog carries the same genes in the same order, but the alleles for each trait may not be the same

30
Q

chromatid

A

either of 2 daughter strands of a duplicated chromosome; separate during cell division to become individual chromosomes

31
Q

prophase I of meiosis I: what occurs during this phase?

A

synapsis
tetrad
crossing over

32
Q

synapsis

A

prophase I; close pairing of homologous chromosomes

33
Q

tetrad

A

prophase I; closely associated four-sister chromosomes of 2 homologous chromosomes

34
Q

crossing over:

A

prophase I; exchange of genetic info, the first mechanism that generates genetic variation in newly formed gametes

35
Q

metaphase I

A

random alignment of homologous pairs of chromosomes along the metaphase plate

36
Q

anaphase I:

A

separation of homologous pairs and random distribution; second mechanism of generating genetic variation in newly formed gametes

37
Q

telophase I

A

cytoplasm divides and chromosomes at opp poles

38
Q

interkinesis

A

spindle breaks down, chromosomes relax, and nuclear envelope re-forms; no DNA synthesis