Exam 1: Ch 3 Protenomics Flashcards
1
Q
protenomics
A
systematic study of the amounts, modifications, interactions, localization, and functions of all or subsets of proteins at the whole-organism, tissue, cellular, and subcellular levels
2
Q
what sparked protenomics
A
genome sequencing
3
Q
questions asked in protenomics
A
in a given sample what fraction of the protenome is expressed and what are their abundances?
which proteins are present in large complexes and what are their functions
do certain cancers or heart disease cause characteristic changes in blood proteins?
can changes in the protenome help define targets for drugs
4
Q
high throughput LC-MS/MS
A
used in protenomics to identify which proteins are in which organelles
