Exam 1: Ch 1 Flashcards

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1
Q

charles darwin

A

natural selection: organisms vary randomly and compete within their environment for resources

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2
Q

what are genes?

A

strands of DNA that code for proteins

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3
Q

mutation

A

an alteration in the structure and organization of a gene

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4
Q

metazoan definition

A

multicellular animal

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5
Q

water accounts for how much of a cell’s volume?

A

75%

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6
Q

ATP

A

adenosine triphosphate

cell’s primary source of energy

energy stored in two of its chemical bonds

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7
Q

ADP

A

adenosine triphosphate

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8
Q

photosynthesis

A

plants and some organisms harvest energy from the sun

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9
Q

proteins are commonly made of how many aas?

A

100-1000

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10
Q

enzyme

A

protein that catalyzes chemical reactions without being consumed or changed

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11
Q

cytoskeletal proteins

A

structural components of a cell that form an internal skeleton

also power movement of structures using ATP

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12
Q

when did Watson & Crick propose the structure of DNA

A

60 yrs ago

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13
Q

2 regions of genes

A

coding region: aa sequence of a protein

regulatory region: binds specific proteins and controls when and in which cells the protein is made

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14
Q

how many genes do humans have

A

~ 20,000-23,000

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15
Q

transcription

A

coding region of a gene is copied into mRNA by RNA polymerase

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16
Q

RNA polymerase

A

large enzyme that catalyzes that linkage of nt into RNA using DNA as a template

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17
Q

translation

A

ribosome reads mRNA and translates a protein

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18
Q

transcription factor

A

DNA-binding proteins that alter gene expression

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19
Q

what are phospholipid bilayers impermeable to

A

water

ions

hydrophillic small molecules

20
Q

4 kingdoms of eukaryotes

A

plants

animals

fungi

protists

21
Q

5th and 6th kingdoms

A

bacteria

archae

22
Q

model organisms

A

systems in which the study of cellular function and development serve as a model for other species

23
Q

bacteria basics

A

1-2 micrometers

plasma membrane, cell wall (peptidoglycan) cytoplasm, circular DNA chromosome, ribosomes in cytoplasm, mesosome (invagination)

24
Q

gram neg/pos

A

neg: inner cell wall & outer membrane separated by periplasmic space
pos: thicker cell wall and no outer membrane

25
Q

archae extreme conditions?

A

yes

26
Q

eukaryote basics

A

10-100 micrometers

plasma membrane, organelles, membrane enclosed nucleus, mitochondria (chloroplasts in plants)

27
Q

lysosome

A

organelle with a lower pH 5.0

break down parts of the cell into small molecules

28
Q

cytoskeleton

A

gives cell strength and rigidity

cell shape

29
Q

cytoskeleton fibers

A

microtubule: 20nm, protein tubulin

intermediate filaments: 10nm, rod-shaped subunits

microfilaments: 7nm, protein actin

30
Q

cell-adhesion proteins

A

animal cells are glued together

31
Q

basal lamina

A

tough matrix of proteins and polysaccharides

forms a supporting layer underlying cell sheets and prevents cell aggregates from ripping apart

32
Q

plasmodesmata

A

cytoplasmic bridges in some plants

33
Q

endothelium

A

layer of endothelial cells

prevent blood cell from leaking out of vessels

34
Q

protostomes

A

develop a mouth close to a transient opening in the early embryo (blastopore)

have a ventral nerve chord

worms insects mollusks

35
Q

deuterostomes

A

develop an anus close to this transient opening in the embryo

have a dorsal central nervous system

echinoderms and vertebrates

36
Q

patterning genes

A

specify the general organization of an organism beginning with major body axes

conserved in both protostomes and deuterostomes as master transcription factors

eyeless in fruit flies and pax6 in humans are genes for eye development

37
Q

virus

A

protein coat covering a core of genetic material

38
Q

evolution

A

genetic change in a population over time

through evolution all organisms are related in a family tree

39
Q

which isomer of aas are found in proteins

A

L, not D

40
Q

mesosome

A

bacterial invagination of cell membrane associated with synthesis of DNA and secretion of proteins

41
Q

peptidoglycan

A

complex of proteins and oligosaccharides that make up the cell wall of bacteria

42
Q

E. coli as a model organism

A

grow rapidly, possess mechanisms for controlling gene regulation

have proteins involed in DNA, RNA, and protein synthesis

43
Q

peroxisome

A

small organelle specialized for breaking down lipid components of membranes

44
Q

endoplasmic reticulum

A

organelle that produces, processes, and ships proteins and lipids

usually ship to golgi complex

45
Q

golgi complex

A

organelle that modifies proteins and lipids before transporting to final destination

46
Q

yeast as a model organism

A

identification of many proteins that regulate cell cycle and catalyze DNA replication/transcription

grow easily and clones have same genes and biochemical properties