Exam 1: Ch 1 Flashcards
charles darwin
natural selection: organisms vary randomly and compete within their environment for resources
what are genes?
strands of DNA that code for proteins
mutation
an alteration in the structure and organization of a gene
metazoan definition
multicellular animal
water accounts for how much of a cell’s volume?
75%
ATP
adenosine triphosphate
cell’s primary source of energy
energy stored in two of its chemical bonds
ADP
adenosine triphosphate
photosynthesis
plants and some organisms harvest energy from the sun
proteins are commonly made of how many aas?
100-1000
enzyme
protein that catalyzes chemical reactions without being consumed or changed
cytoskeletal proteins
structural components of a cell that form an internal skeleton
also power movement of structures using ATP
when did Watson & Crick propose the structure of DNA
60 yrs ago
2 regions of genes
coding region: aa sequence of a protein
regulatory region: binds specific proteins and controls when and in which cells the protein is made
how many genes do humans have
~ 20,000-23,000
transcription
coding region of a gene is copied into mRNA by RNA polymerase
RNA polymerase
large enzyme that catalyzes that linkage of nt into RNA using DNA as a template
translation
ribosome reads mRNA and translates a protein
transcription factor
DNA-binding proteins that alter gene expression
what are phospholipid bilayers impermeable to
water
ions
hydrophillic small molecules
4 kingdoms of eukaryotes
plants
animals
fungi
protists
5th and 6th kingdoms
bacteria
archae
model organisms
systems in which the study of cellular function and development serve as a model for other species
bacteria basics
1-2 micrometers
plasma membrane, cell wall (peptidoglycan) cytoplasm, circular DNA chromosome, ribosomes in cytoplasm, mesosome (invagination)
gram neg/pos
neg: inner cell wall & outer membrane separated by periplasmic space
pos: thicker cell wall and no outer membrane
archae extreme conditions?
yes
eukaryote basics
10-100 micrometers
plasma membrane, organelles, membrane enclosed nucleus, mitochondria (chloroplasts in plants)
lysosome
organelle with a lower pH 5.0
break down parts of the cell into small molecules
cytoskeleton
gives cell strength and rigidity
cell shape
cytoskeleton fibers
microtubule: 20nm, protein tubulin
intermediate filaments: 10nm, rod-shaped subunits
microfilaments: 7nm, protein actin
cell-adhesion proteins
animal cells are glued together
basal lamina
tough matrix of proteins and polysaccharides
forms a supporting layer underlying cell sheets and prevents cell aggregates from ripping apart
plasmodesmata
cytoplasmic bridges in some plants
endothelium
layer of endothelial cells
prevent blood cell from leaking out of vessels
protostomes
develop a mouth close to a transient opening in the early embryo (blastopore)
have a ventral nerve chord
worms insects mollusks
deuterostomes
develop an anus close to this transient opening in the embryo
have a dorsal central nervous system
echinoderms and vertebrates
patterning genes
specify the general organization of an organism beginning with major body axes
conserved in both protostomes and deuterostomes as master transcription factors
eyeless in fruit flies and pax6 in humans are genes for eye development
virus
protein coat covering a core of genetic material
evolution
genetic change in a population over time
through evolution all organisms are related in a family tree
which isomer of aas are found in proteins
L, not D
mesosome
bacterial invagination of cell membrane associated with synthesis of DNA and secretion of proteins
peptidoglycan
complex of proteins and oligosaccharides that make up the cell wall of bacteria
E. coli as a model organism
grow rapidly, possess mechanisms for controlling gene regulation
have proteins involed in DNA, RNA, and protein synthesis
peroxisome
small organelle specialized for breaking down lipid components of membranes
endoplasmic reticulum
organelle that produces, processes, and ships proteins and lipids
usually ship to golgi complex
golgi complex
organelle that modifies proteins and lipids before transporting to final destination
yeast as a model organism
identification of many proteins that regulate cell cycle and catalyze DNA replication/transcription
grow easily and clones have same genes and biochemical properties