Exam 1: Cell Adaptation Flashcards
What are the principle responses of cellular adaptation?
atrophy
hyperplasia
hypertrophy
metaplasia
and dysplasia
A decrease in size or number of cells is called what?
atrophy
will also have decrease in metabolic activity and decreased protein synthesis (gradual protein degradation)
a reduction in cell numbers (not size) is called what?
apoptosis
What is indicated on this histology slide?
area of atrophy
What is indicated on this histology slide?
Atrophy
What is shown in this image?
atrophy of the liver (see the size of the gall bladder)
What is shown in this image?
Atrophy of fat of the heart
What does atrophy of fat look like?
Gelatin like, serous, fat looks like water.
moderate atrophy make look like you cooked it a little
What is shown on this heart? what could be a potential cause?
serous atrophy of fat;
negative energy balance, possibly from malnutrition, malabsorption of nutrients or parasitic infection
What is shown in this image?
atrophy of fat in the bone marrow (loss of pinkish color and shrinking in size)
What is shown here and what is a sign?
Cardiac hypertrophy; globus shape
What is shown in this histology slide of cardiomyocytes?
hypertrophy. Note the squiggly lines
HCM is caused by what gene in Maine Coone Cats?
MYBPC3 gene
How would you diagnose a heart that you suspected had hypertrophy?
by shape - globus
measure the ventricular walls, if L is 3x> than R, suspect
weigh the heart, normal heart is 0.03% of BW is suspect (>18g in cat is suspect)
Where does physiological hypertophy happen?
uterus during pregnancy – hormonal
muscles in weightlifters
What is shown here?
hyperplasia of the gingiva
