Exam 1 Flashcards

You may prefer our related Brainscape-certified flashcards:
1
Q

definition of health

A

A state of complete physical, mental, and social well-being and not just the absence of disease or infirmity

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

psychology

A

the study of the mind and behavior ⇒ embraces all aspects of the human experience from the functions of the brain to the actions of nations, from child development to care for the aged

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

health psychology

A

the aggregate of special educational, scientific, and professional contributions of the discipline of psychology to the promotion/maintenance of health, prevention/treatment of disease, the identification of etiologic and diagnostic correlates of health, illness, and related dysfunction, and the analysis and improvements of the health care system and health policy formation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

health psychology goals (4)

A
  1. Promote and maintain health
  2. Prevent and treat illness
  3. Understand etiology and diagnosis
  4. Improve health care system and policy
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

what is the solution to the problem of ill health in America?

A

individual responsibility and social responsibility through public legislation and private volunteer efforts

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

BPS Model (BPSM)

A

biopsychosocial model
1. biological systems => immune, hereditary
2. psychological systems => personality, interests, competitiveness
3. proximate social systems => family, athletics, friends, school
4. distal social system => government, state legislature

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

things patients consider (5)

A
  • how long they wait to see you
  • How readily they disclose their symptoms
  • What they want in terms of the visit or treatment
  • How your knowledge of them affects your diagnosis
  • How they will comply with your prescribed treatment
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

who were the people of Roseto?

A

Italian American immigrant community with less heart disease than most of the rest of America due to culture, habits, and emotional safety => went away as they Americanized

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

Trepanning

A

Drilled holes in the skull for patient with headaches or epilepsy where evil spirits need to be released => medical and religious

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

imhotep

A

god of medicine 2670 BCE famous for his skills when we lived as a doctor (Egypt)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

ancient egyptian medical practices

A

Physicians, surgeons, and spiritualists (invoke supernatural forces => Human excretions, hippo fat, specialized tools for surgeries like fractures and cysts, spiritualists treated with incantations

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Ebers papyrus

A

medical classifications and treatments c. 1550 BCE (Egypt)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

ancient middle eastern medicine

A

Mesopotamia ⇒ Iraq, syria, turkey, and iran
- If a patient died the doctors hand may be cutoff, Gods and astrology, Mesopotamian tablets c. 650 BCE: lists medical conditions and treatments
Regulation of medical practice

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

ancient india medical practices

A

docs used incantations, surgery, vital energy channels, and points on the body important for different function

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ayurveda

A

life wisdom with the 5 elements (space, air, fire, water, earth)
- health was based on individual element balance and illness is due to elemental excess so treatments like detoxification, herbs, food, yoga, meditation combated this (India)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ayurveda health categories (3)

A
  1. Vata dosha (movement): space (lightness) and air (coldness, dryness, mobility)
  2. Pitta dosha (transformation): fire (heat, illumination), water (fluidity)
  3. Kapha dosha (binding): water, earth (stability, solidity)
    - someone dominant dosha is what shapes their body and personality
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

what is special aboutn ancient china?

A

moves away from ancient health practices of spiritualism to health

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

ancient chinese medical practices

A

Medicine became separate from religion and magic c 400 BCE, Grading systems of medical professionals , Vital energy channels and points on the body important for different functions , Nei Ching c. 479 BCE ⇒ chi and its path

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

traditional chinese medicine

A

5 basic elements: fire, water, earth, wood, metal, Health based on individual elemental balance, Health also based on balance between complementary forces yin and yang, Treatment inlide hearbs, tai chi, and acupuncture and focus on restoring elemental balance and energetic flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

Asklepios (Greek) and Aesculapius (Roman)

A

god of medicine with temples for treatment => psyche/soul became the domain of philosophers, body is its slave

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

Empedocles

A

philosphopher who came up with 4 elements => Air, earth, fire, and water, psych is in the heart (Greek)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

Plato and Aristotle

A

philosophers (Plato came first) with rationale and irrational souls, localization of psych functions => Did the soul control the body or did the body control the soul? (Greek)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

What is special about roman and greek medicine?

A

shifts to natural explainations from spiritual ones (same as in China)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

Hippocrates

A

asserts disease is due to natural causes, father of western medicine, hippocrates oath, humoral theory based on on elements c. 400 BCE
Blood, black bile, yellow bile, and phlegm (Greek)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
25
Q

Galen

A

physician and writer, continued humoral theory but also noticed in surgery that disease could be localized, soul is the slave of the body => soul is in the head (Greek)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
26
Q

According to galen Air, Earth, Fire, and Water correlate to which of his 4 elements

A
  1. A = blood
  2. E = black bile
  3. F = yellow bile
  4. W = phlegm
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
27
Q

dark ages period

A

(500-1500 CE) long pause in western inquiry, llumination from intellectualism was snuffed out from the church, Left theoriests of the human body and soul hiding in the shadows, Many people were dying from the plague as well took away stability for intellectual inquiry

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
28
Q

the renaissance period

A

(1300-1500 CE) Rebirth of inquiry and culture from religion centered to human centered

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
29
Q

Da vinci (1452-1519)

A

anatomy through art

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
30
Q

Vesalius (1515-1564)

A

physician and artist, 7 volumes about human body, anatomical pathology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
31
Q

the scientific revolution (person + 4 techniques)

A
  • Descartes (1956-1650) body analogous to a machine, separate soul, dualism
  • Microscopy
  • Cell theory and microbes discovery
  • Germ theory
  • Phrenology
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
32
Q

what was speical about the scientific revolution

A

we wanted to localize personality to parts of the brain
- identified criminals and undesirables

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
33
Q

present and near future medical technology

A
  • pathology
  • genetics
    -microbiome
  • neuroscience
  • dualism
  • monism
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
34
Q

neuroscience

A

localization and physiology of psychological function based on minimally invasive technology
- Flow of chemical and electrical activity
- Increasingly precise locations in the brain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
35
Q

dualism

A

body and soul

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
36
Q

monism

A

body alone

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
37
Q

major social factors of infectious disease (3)

A
  • Poor, overcrowded housing
  • Lack of clean, public water supply
  • Lack of waste control
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
38
Q

most deadly diseases past and present

A

past: pneumonia, tuberculosis, diarrhea, enteritis
present: heart disease, cancer, strokes => diabetes, obesity, arthritis, chronic health conditions overall

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
39
Q

what was child mortality in the 1900s?

A

30% under childen age 5 => became 2% by 1997

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
40
Q

factors changing infectious morbidity and mortality

A
  1. Improvements in sanitation and hygiene
  2. Vaccinations
  3. Discovery of antibiotics ⇒ prescribed for previous life threatening bacterial infections
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
41
Q

what outbreak happened in London later?

A

cholera

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
42
Q

stress

A

occurs when an individual perceives that environmental demands tax or exceed their capacity ⇒ process of an individual response (perception)
- first coined in bridge engineering

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
43
Q

stressors

A

refers to the experience or circumstance that provokes a response => Can reside in the individual or can come from conflict with family members or from the community

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
44
Q

stress sources

A

community, family, self, physical, psychological

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
45
Q

acute vs chronic stress

A

short lived vs extended periods of time

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
46
Q

appraisal (lazarus) => primary vs secondary vs reappraisal

A

subjective experience
1. Primary appraisal: initial judgment about relevance and significance ⇒ such as am I in trouble
2. Secondary appraisal: when we determine something is stressful ⇒ what can I do about it
3. Reappraisal: evaluate our response ⇒ how did things go and whats next

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
47
Q

stressor characteristics (5)

A

negative, ambiguous, uncontrollable, overwhelming, important

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
48
Q

system

A

collection of coordinated body parts and the chemicals they produce

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
49
Q

Sympathetic nervous system

A

the neural connection to many parts of the body and results in mental alertness, pupil dilation, rapid breathing, increased energy, sweating, dry mouth, stalled digestion, urination, and bowel emptying

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
50
Q

parasympathetic

A

brings restoration after stress

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
51
Q

Sympathetic adrenal medullary (SAM)

A

core of the adrenal gland and a collection of cells that sit above the kidneys ⇒ release chemicals into the bloodstream to activate the sympathetic nervous system
- nervous and hormonal systems
- epinephrine and norepinephrine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
52
Q

Epinephrine

A

adrenaline to activate fight or flight, above the kidneys ⇒ signal stimulated by the adrenal medullary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
53
Q

Norepinephrine

A

increases alertness and attention
and another signal stimulated by the adrenal medullary

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
54
Q

what is fight or flight?

A

provides urgent energy needed for survival, the body increases oxygen and blood flow to muscles, and stops other processes
- Parasympathetic calms the body down afterward

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
55
Q

Homeostasis

A

state where the body has reached balance again

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
56
Q

HPA Axis

A
  • comes from Selye
  • Hypothalamus (head) => corticotropic releasing hormone
  • Pituitary (head) => adrenocortitoctropic hormone
  • Adrenal(kidney) => cortisol
  • acts as a negative feedback system
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
57
Q

cortisol

A

released from the adrenal gland which calms the body system down and stimulates the release of glucose to feed muscle cells
- trvels back up to the hypothalamus and pituitary gland for calm
- high cortisol can cause weight gain, acne, and fatigue

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
58
Q

does HPA or SAM work faster?

A

SAM does => HPA is a hormonal response compared to a nerve response

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
59
Q

Who is Selye and what did he discover?

A

fathered stress research and did experiments on rats while conducting post mortem analysis to see what changes occurred to their organs
- adrenal hypertrophy, thymus atrophy, gastric ulceration
- he also came up with the GAS

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
60
Q

general adaptation syndrome

A

Alarm, resistance, exhaustion which can result in disease or death if gone on for too long

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
61
Q

allostasis and allostatic load

A

differing from normal equilibrium balance through change; cost of allostasis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
62
Q

how do relationships affect allostatic load?

A

we respond to nurturance and social affiliation to produce oxytocin, vasopressin, and endorphins (& dopamine) from the pituitary gland give us a sense of wellbeing and reward
- women engage in this more and get more benefit
- we all produce oxytocin (more common in females for bonding) and vasopressin (more common in males for bonding)

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
63
Q

What did James lange believe

A

physiological response over emotional response => body is triggered first

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
64
Q

what did Cannon-bard and Lazarus believe

A

cognitive response over physiological response => conscious is triggered first

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
65
Q

what did DeLouix believe?

A

physiological vs emotional stress response depends because sometimes the body reacts faster and other times the cognitive process causes reactions later

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
66
Q

questionnaire measurement considerations for stress (8)

A
  • stressor inclusion
  • stressor intensity
  • stressor duration
  • experimental control vs ecological validity
  • physiological variables
  • physiological outcomes
  • psychosocial and behavioral outcomes
  • frequency of measurement
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
67
Q

experimental control vs ecological validity

A

things that happen in real life may need to be sacrificed to fully control the stressor in a study and make it the same across individuals

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
68
Q

psychosocial and behavioral outcomes

A

how does life produce more stress for certain people such as in vocation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
69
Q

adult life questionnaire examples

A

Holmes and Rahe
spouse death, divorce, marital separation, jail, pregnancy, children leaving, changing residence, vacation, eating habits

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
70
Q

adolescent life questionnaire examples

A

Yaeworth; Holmes and Rahe
parent death, sibling death, friend death, parent divorce, losing jobs, change in physicality, starting a job, sibling marriage

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
71
Q

hassles and uplifts scale

A

DeLongis, Folkman, and Lazarus
smaller events in our lives that tend to occur more frequently; The sum of both your hassles and sum of your uplifts for a given time period gives you a rating

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
72
Q

time sampling

A

trades questionnaires or combines questionnaires with short frequent inquiries at certain times of the day over a phone call or a time slot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
73
Q

physiological measurement examples (2)

A

biochem assays => epinephrine/norepinephrine (blood), cortisol (blood and saliva)
polygraph devices to measure SAM => respiration, blood pressure, Galvanic skin response (sweat/conductance), heart rate

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
74
Q

how does stress negatively affect health (2)

A
  • direct physiological => SAM, HPA, chronic activation
  • behavior and illness => sleeping, eating, smoking, drinking, drugs, medical attention, treatment adherance, changes in social life
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
75
Q

stress physical health associations (9)

A
  1. cardiovascular disease (CVD)
  2. gastrointestinal
  3. Immunity
  4. Cancer
  5. blood and sugar and fat
  6. Growth
  7. reproduction
  8. Aging
  9. Pain
How well did you know this?
1
Not at all
2
3
4
5
Perfectly
76
Q

cardiovascular disease

A

(individual differences, intermediate CVD, advanced CVD)
#1 casue of death b/c cholesterol can accumulate which obstructs blood flow and bulges inward => Plaque can rupture into the lumen or arterial opening which triggers the body’s repair response that involves clotting to seal the wound
- Increased blood pressure
- Arterial damage
- Increased plaque formation
- Inflammation and coagulation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
77
Q

ischemia

A

inadequate blood supply to an organ which reduces blood flow

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
78
Q

angina

A

chest pain

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
79
Q

infarction

A

tissue dies due to a lodged blood clot

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
80
Q

atherosclerosis

A

thickening of the arteries which makes them less flexible and less able to respond to changes in blood pressure => more damage likely

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
81
Q

gastrointestinal stress

A

exacerbate ulcers and IBS, SAM shuts down digestion making stomach lining vulnerable, diarrhea, constipation, HPA stimulates/suppresses appetite

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
82
Q

immunity stress response

A

sometimes increases and sometimes decreases depending on the type of stress response and duration

83
Q

cancer and stress

A

highly mixed studies but animal research finds tumor initiation, growth, metastasis, and may act through immune system defenses, DNA repair, or cellular aging

84
Q

blood sugar and fat stress response

A

increased blood sugar and fats from released storage, increases insulin resistance and diabetes due to blockage by cortisol, higher sugar and fat in blood contributes to CVD/damaged nerves

85
Q

growth stress response

A

reduced growth hormone from pituitary gland due to neural and cortisol input (cortisol blocks calcium uptake), reduced bone growth and increased bone weakness, digestive problems

86
Q

psychogenic dwarfism

A

extreme chronic stress can inhibit growth in children

87
Q

reproduction and stress

A

reduces reproductive hormones, disrupts gamete production, sex drive, interferes with sex performance, misscarriages

88
Q

Aging and stress

A

stress speeds up aging due to telomere shortening, hippocampal problems and memory problems from cortisol inhibiting insulin/glucose entry, stress response declines, prolonged effects, resting chemicals are higher

89
Q

what lifestyle factors are telomeres associated with

A

food, sleep, exercise, tobacco/alcohol, etc.

90
Q

pain and stress

A

decreased pain perception in short term but increased pain perception chronically

91
Q

research challenges (7)

A
  1. Differences in stage of disease and lack of identification and access at early stages
  2. Differences in disease subtypes
  3. Differences in types of stressors, including frequency and duration
  4. Differences in timing of stress to disease process
  5. A disease process may be very slow and thus difficult to follow ⇒ decreased participation and continued funding
  6. Lack of control in human studies ⇒ disease and stressor variability
  7. Animal models may not be applicable to humans
92
Q

Psychoneuroimmunology (PNI)

A

how a psychological experience effects immune functioning and nervous functioning

93
Q

complement immunity

A

collection of circulating proteins that complement antibodies (another set of proteins used by the immune system)
- damage invaders, attract immune cells to a site, bind to invaders and tag them

94
Q

Leukocyte types; where they are found

A
  • phagocytes: eat invader cells
  • lymphocytes: cells of the lymph that attack and destroy invaders
  • scattered throughout blood vessels, tissues in interstitial fluid, and lymphatic system
95
Q

lympathic system components

A

cardiovascular and lymph where smooth muscles help move the fluids from the body to the neck where they drain into the veins of the cardiovascular system

96
Q

nodes

A

(swelling) located along the vessels where immune system cells gather and filter cellular waste, dead cells, and pathogens
- invader cells or cancer cells may be brought here so immune systems can destroy them

97
Q

lymth

A

colorless liquid that passes from the blood into the tissues and into the lymph vessels before going back to the blood vessels
- moved by your body movements and its muscles but not pumped

98
Q

what does lymph do?

A

Carries cellular waste, dead cells, and pathogens and transports white blood cells

99
Q

Organs of the immune system (5)

A
  • Tonsils: lymph nodes at the junction of your oral cavity and throat
  • Thymus gland: behind your sternum and site of maturation for some immune cells
  • Spleen: behind your stomach and is a hybrid of cardiovascular and lymph systems
  • Bone marrow: source of immune stem cells ⇒ some mature and some are sent to the thymus gland
  • Intestines: fats are transported from the small intestine to the lymph system before entering the blood => High amounts of fat gives lymph and plasma a milky appearance
100
Q

Non-specific immunity components

A
  1. barriers like the skin
  2. complement proteins labeling pathogens
  3. phagocytosis where macrophages will eat cells that are labeled
  4. toxins using chemical warfare from complement proteins and immune cells
  5. inflammation
  6. cytokines
101
Q

inflammation defense system

A

triggered by complement proteins, cytokines, and immune cells
- Making blood vessels dilate, producing redness, leak plasma which causes swelling to bring immune cells to the affected area

102
Q

cytokines

A

chemical messages that moves another cell to act within and beyond the immune system
- Very important for the coordinated action the immune system can take against an invader

103
Q

major functions of nonspecific immunity (5)

A
  • Block entry of pathogens
  • Recognize non-self materials
  • Congregate at site of wound or infection and release toxins and ingest pathogens
  • Stimulate inflammation
  • Communicate the news of invasion to other immune cells
104
Q

specific immunity major players (3)

A

lymphocytes: white blood cells produced in bone marrow and travel throughout the lymphatic system
- T cells, B cells, Natural killer cells which have receptors specific to particular pathogens (cellular memory)

105
Q

T cells

A

(T = thymus where they finish maturing) destroy pathogens or the body’s own cells that have been taken over by viruses and also send signals to help control the immune systems response to threats

106
Q

B cells

A

(B = bone marrow where they finish maturing) make proteins called antibodies to fight pathogens

107
Q

Natural killer cells

A

recognize specific targets through the genetic code and will attack these certain targets
- finish maturing in the bone marrow

108
Q

Major functions after pathogen interaction (4)

A
  • Lymphocyte production ⇒ make copies of themselves to increase disease fighting cells
  • Antibody production ⇒ pathogen identification and tagging and communicate information about the pathogen
  • Communication (cytokines) ⇒ activation of other cells
  • Recognition ⇒ memory
109
Q

deficiency (2 subcategories)

A

persons may be born a certain way or they can be acquired by infection
- congenital (birth defects) or acquired

110
Q

autoimmunity

A

immunity directed at the self by a trigger

111
Q

Asthma

A

excessive inflammatory response in the lungs and air passages

112
Q

Anaphylaxis

A

a substance is encountered (bee sting or peanuts) which triggers antibody formation but antibodies linger and when the substance is encountered again the antibodies trigger a systemic inflammatory response

113
Q

Type 1 Diabetes

A

partly due to genes that result in immune cells attacking the pancreas and destroying cells that make insulin

114
Q

Multiple Sclerosis

A

attack on the myelin surrounding nerve fibers which prevents them from successfully and quickly transmitting signals

115
Q

PNI connections (3)

A
  • Stress => emotion, physiology, behavior
  • Central nervous system => brain and spinal cord
  • Autonomic nervous system => sympathetic and parasympathetic NS
116
Q

immunology

A

the immune system made up of cells and cytokines

117
Q

what does the sympathetic NS innervate?

A

lympth structures like Spleen, thymus, bone marrow, lymph nodes, lymphocytes

118
Q

what does the vagus nerve innervate?

A

lymph structures => T cells > macrophages of the spleen = reduced inflammation

119
Q

hypothalamus lesions do what?

A

decrease some immune functions => hypothalamus stimulation increases immune functions

120
Q

what neurotransmitter receptors are found on immune organs and lymphocytes?

A

epinephrine, norepinephrine, and dopamine

121
Q

nociceptors

A

peripheral pain sensory neurons that can activate the immune cells

122
Q

when does psycho-neuro overpower the immune system?

A

SNS, vagus n., hypothalamus, neurotransmitters

123
Q

when is immuno system > psycho-neuro?

A

when cytokines are activated => which affect neurotransmitters and turn on/off pain receptors
- cytokines stimulate SAM and HPA activity and nociceptors and the hypothalamus to make us sleepy

124
Q

classical conditioning of the immune system

A

the unconditioned stimulus (US) brings an unconditioned response (UR) and the continued stimulus (CS) causes a conditioned response (CR)
- ex women who receive chemotherapy have immunosuppression when entering the hospital

125
Q

acute stress is linked to what?

A

some increase in non-specific immunity

126
Q

chronic stress is linked to what?

A

decreased immunity both specific and non specific

127
Q

how does stress affect viral recovery?

A

when you are more stressed you suffer from worse symptoms and have a higher viral count

128
Q

how does stress affect vaccinations?

A

when you are more stressed out you develop less antibodies

129
Q

how does viral reactivation get affected by stress?

A

stress will cause lifelong viruses like epstein barr or herpes to reactivate

130
Q

how does stress affect healing and recovery?

A

it slows wound healing down as well as recovery in general

131
Q

how do acute stressors affect us

A

Increase in non-specific immune responses and Decreases in specific immune response

132
Q

how do brief naturalistic stressors affect us

A

Some decreases and some increases in non specific responses; Decrease in specific cellular response/lymphocyte production, but increase in specific antibody responses

133
Q

how do event sequence stressors affect us?

A

some decreases, some increases, and some that didn’t change

134
Q

how do chronic stressors affect us?

A

Very little change in immune cell numbers but wide spread decreases in function and evidence for viral reactivation; Decreases in nonspecific and specific alongside viral reactivation

135
Q

how does severe trauma affect us?

A

No consistent changes

136
Q

how did people on questionnaires get affected by stress?

A

Decreases in immune function for older (+55) and ill (HIV/aids), not young and healthy; Young and healthy individuals are unaffected or resilient ⇒ older and chronic health condition were more vulnerable

137
Q

how are people affected globally by stress?

A

No consistent changes

138
Q

Meta analysis highlights (4)

A
  1. Acute stressors were associated with increased nonspecific immunity
  2. Chronic stress was associated with decreased immunity
  3. Age and illness made the immune system more vulnerable to stress effects
  4. No support here for appraisal being related to immunity
139
Q

conclusions for stress immunity (6)

A
  • Too simplistic
  • Sometimes suppresses chronic and sometimes activates acute
  • Can suppress some aspects but activate others
  • Patterns of activation and suppression differ with stressors and individuals
  • Much more research is needed to find consistent patterns among the effects
  • Research is needed to link immune changes to disease
140
Q

emotion focused coping functions

A

strategies that work to decrease negative emotions or increase positive emotions
- Used more often when it is believed change isn’t possible

141
Q

problem focused coping functions

A

strategies that work to change or eliminate the source of stress
- it appears we cope best when we can change our strategies based on the particular event

142
Q

preventative coping methods

A

strategies that reduce the likelihood of stressors or lessen their impact should they occur ⇒ proactive strategies

143
Q

combative coping methods

A

strategies that are employed in the face of a stressor to eliminate it or lessen its impact

144
Q

expressive writing

A

writing about traumatic experiences
- This confronts their related thoughts and emotions ⇒ reduces stress when writing is over but can raise anxiety during the activity

144
Q

mindfulness-based stress reduction (MBSR)

A

these techniques focus the mind and gaining insight into one’s thought and more control over reactions to experiences
- Activates the prefrontal cortex which regulates negative emotions

145
Q

self affirmations

A

affirming one’s values through self reflection
- Less distress, less stress physiology, and feel better about oneself

146
Q

relaxation techniques definition

A

reduces tension and feelings of stress in the body
- Reduce stress physiology, inflammation, and blood lipids

147
Q

benefits of positive coping (5)

A
  • Avoid, reduce, or eliminate particular stressors
  • Better adjustment physiologically to negative experiences
  • Reduce stress responses
  • Feel better about oneself
  • Reduce the impact of stress on ones relationships
148
Q

3 aspects of support

A
  1. Support type: the way in which a person helps you
  2. Support network size: how many people you have for support ⇒ individuals and social domains
  3. Support satisfaction: how supported you feel by your people ⇒ perceived quality
149
Q

types of support (6)

A
  1. Emotional: comforting by listening, hugging, or being nearby
  2. Esteem: make us feel values, respected, and needed
  3. Tangible: help from goods and services provided ⇒ money, childcare, medical care, transportation, etc.
  4. Informational: the things we have learned from our people ⇒ jobs, parenting strategies, ideas for medical treatment, etc.
  5. Network: the connections we can access through our people ⇒ medical providers, job openings, etc.
  6. Invisible: given anonymously without a certain person overtly doing it
150
Q

percieved support

A

a person’s belief of available support
- More stable over time, less related to context
- Most correlated with health outcomes and behaviors
- Low levels linked to CVD ⇒ plaque build up, cv reactivity, blood pressure

151
Q

recieved support

A

what is actually provided in a situation
- More dependent on context and circumstances ⇒ can change with each event
- Effectiveness depends on the content and circumstances
- Mixed findings for relationship to health outcomes
- may lead to differences in the relationship between social support and health

152
Q

Benefits of support (6)

A
  • Lower likelihood of illness
  • Speedier recovery from illness
  • Slower disease progression
  • Reduced chance of dying from serious illnesses
  • Increased medical adherence
  • Increased use of medical services
153
Q

stress buffering

A

occurs during the stressor but lessens its harshness
- Affects experience appraisal
- Provides resources to deal with it
- Reduces physiological responses to stress

154
Q

direct effects of stress buffering (6)

A
  • Enhances self esteem
  • Gives a sense of belonging
  • Influences lifestyle and health behaviors
  • Lower blood pressure, less atherosclerosis
  • Lower circulating stress hormones ⇒ epinephrine and cortisol
  • Better immune functioning ⇒ natural killer cell activity and resistance to viral infections
155
Q

factors affecting use of suport (2)

A
  1. environmental factors
  2. the person themself
    - people can learn to better recognize available support and be taught social skills including reduction of social anxiety
156
Q

specific health risks for non-married people

A

CVD, infectious diseases, lung, and liver disease

157
Q

which preceeds the other: health or marriage?

A

healthier people are more likely to get married

158
Q

where do wives vs. husbands get their support?

A

wives get it from their social support networks and husbands get support from their wives most of the time

159
Q

women may be more sensitive to conflict which causes … (2)

A
  • Greater risk of mortality and morbidity due to marital problems
  • Greater immune and stress responses that last longer than husbands
160
Q

marriage dissatisfaction associations (5)

A
  • Higher blood pressure and heart rate
  • Lower self reported general health and higher self reported symptoms
  • Greater pain perceptions
  • Greater inflammatory disease flare ups
  • Ulcer development
161
Q

which bodily systems does marriage quality impact? (3)

A
  • immune
  • endocrine
  • cardiovascular
162
Q

how can marital conflict impair health? (4)

A
  1. There are many opportunities for conflict
  2. Couples may not adapt physiologically, thus producing high stress responses each time
  3. Stress responses from couple-conflicts are slower to recover than from other sources
  4. The risks are greater for troubled, distressed couples chronically
163
Q

how does early social support influence us? (2)

A
  1. Personality, social skills, self esteem, and general perception of social support
  2. Psychological characteristics influences our health behaviors and coping skills which reflects in our health
164
Q

conflict

A

repeated displays of anger and aggression ⇒ emotional or physical

165
Q

non-nurturant

A

emotionally cold and unresponsive

166
Q

life stage symptoms of risky family (3)

A
  1. Childhood
    - Linked to problems with children’s emotional expression, social competence, stress physiology regulation, and higher rates of illness
  2. Adolescence
    - Greater cigarette, alcohol, and drug use
    - Risk in sexual behavior in adolescence from less parental supervision, greater time with peers, and attempts to compensate for poorer social competence and emotional regulation
  3. Adulthood
    - Diseases in adulthood ⇒ CV, lung, liver disease, and fractures
167
Q

risky family health indicators (5)

A
  • Higher blood pressure
  • Higher CV reactivity to a lab challenge ⇒ greater ventricular mass
  • Higher anger and hostility
  • Higher SAM activity due partially to reduced parasympathetic regulation
  • HPA dysregulation ⇒ changes in circadian patterns and greater responses to challenges
168
Q

nurturant mothers result in… (3)

A

low HPA reactivity, faster HPA recovery, and less anxiety

169
Q

what does repeated SAM activation do? (3)

A
  • a more hostile personality that with increased interpersonal conflict will increase health risks
  • HPA system changes may similarly link early experiences and health risks
  • Poorer emotional/stress regulation and social competence (hostility) would negatively affect one’s ability to obtain and maintain social support
170
Q

bereavement

A

the situation of having recently lost a significant person through death

171
Q

grief

A

reaction to bereavement

172
Q

psychological consequences of loss (6)

A
  • Emotional distress
  • Loneliness
  • Changes in social ties and support
  • Changes in living arrangements
  • Changes in economic circumstances
  • Changes in health habits
173
Q

anhedonia

A

loss of pleasure

174
Q

emotional reactions to loss

A

Depression, despair, distress
Anxiety, fear, dread
Anger, hostility, irritability
Anhedonia: loss of pleasure
Loneliness
Yearning, longing, pining
Shock, numbness

175
Q

cognitive reactions to loss

A

Preoccupation with thoughts of deceased, intrusive ruminations
Sense of presence of deceased
Suppression, denial
Lowered self esteem
Self-reproach
Helplessness, hopelessness
Suicidal ideation
Sense of unreality
Memory, concentration difficulties

176
Q

behavioral reactions to loss

A

Agitation, tenseness, restlessness
Fatigue
Overactivity
Searching
Weeping, sobbing, crying
Social withdrawal

177
Q

physical reactions to loss

A

Loss of appetite
Sleep disturbances
Energy loss, exhaustion
Somatic complaints

178
Q

T/F there are differences across cultures in emotion, cognitive, and somatic reactions after loss

A

F => May be differences in use of medical services and in presenting symptoms

179
Q

mortality risk for spouse loss

A

Increased risk appears greatest for husbands
Increased risk appears to persist up to a year for wives and 2 years for husbands
- actual numbers are low with 5% widowers vs 3% married men over 55 dying in the first 6 months

180
Q

mortality risk for child loss

A
  • increased risk of death by suicide for both parents, but higher and more long lasting in mothers
  • Mothers have increased risk of death by natural and unnatural causes lasting as long as 18 years after the loss
  • Mothers at increased risk for psychiatric admission during first year after loss
  • Mothers report poorer health than fathers
  • Mothers health improves over time but fathers health declines
181
Q

morbidity symptoms after bereavement (5)

A
  • Increased illness and disability
  • Increased use of medical services
  • Decreased use of needed medical services
  • Increased drug use
  • Weight loss
182
Q

somatic symptoms after bereavement (4)

A

Headaches
Dizziness
Indigestion
Pain

183
Q

bereavement therapy

A

grief work with acceptance, experiencing grief, adjusting to changed environment, moving on
- Therapy is most effective for those asking and with pre-existing psychological conditions
- Social isolation, rumination, and pre-existing psychological issues associated with poorer outcomes
- Positive reappraisal and meaning making are beneficial

184
Q

What are the 2 main types of study design in health research?

A
  1. Observational: studies where you observe your variables but don’t interject
  2. Experimental: studies where you change your variables and hold all other factors constant as much as possible
185
Q

Study Types in Health Science

A
  1. systematic review and meta analysis
    experimental:
  2. randomized controlled trial
  3. quasi experiment => non randomly assigned
    Observational:
  4. cohort study => follows group of people
  5. case control study => compares histories of 2+ groups
  6. cross sectional survey => broad population
  7. case reports
186
Q

hierarchy of evidence

A
  1. systematic reviews
  2. randomized controlled trials
  3. cohort studies
  4. case control studies
  5. case series, case reports
  6. editorials, expert opinion
187
Q

peer review

A

independent experts read over a paper that has been submitted to a journal

188
Q

impact factor

A

a measure of popularity in scientific journals which tells you how many times a journals paper has been mentioned in future papers relative to the journals volume of article output

189
Q

secret behind science of stress

A

Some degree of stress can actually benefit people

190
Q

Based on the Kolata article, how would you answer the question, is there a link between stress and cancer?

A

No, stress does not cause cancer (not proven yet, mixed reviews). Proteins on cancerous cell surfaces turn off the immune response. It has some support from animal models

191
Q

How do researchers think that MBSR may help people with heart disease?
What have they found so far?

A

MSBR has beneficial effects on anxiety and depression in patients with heart disease
Needs further study with patients who have cardiovascular disease

192
Q

Why are these researchers studying MBSR? What have they found so far?

A

MSBR is linked to better sleep and reduced insomnia

193
Q

What are the 7 ways Albin claims that dogs can help your health?

A
  1. Reduction in respiratory illnesses
  2. Cardiovascular health
  3. Anxiety
  4. Loneliness
  5. Rehabilitation
  6. Activity
  7. Less doctor visits
194
Q

What is the take home message regarding resilience according to Carey?

A

People who have suffered from a couple of adverse life events are the most resilient

195
Q

What does Hackman suggest are the 5 hacks for exam stress?

A

Hugs
Smile
Breathe
Sleep
Think

196
Q

What is an ambivalent marriage? What was the relationship of marital quality and blood pressure in the BYU study?

A

Ambivalent marriage: when the relationship is not always terrible but also not always great ⇒ a partner may be unpredictable or negative ⇒ positive and negative feelings
- Marital quality and blood pressure showed that those in ambivalent relationships had higher systolic blood pressure readings during a given day ⇒ shows cardiovascular health may not be as robust for couples in ambivalent marriages

197
Q

What are the BPS variables of the Ohio State study? If you were to create a drawing (figure) to model the relationships of these variables what would it look like?

A

Lack of sleep ⇒ the couples with 7+ hours of sleep had different tones with one another
- Ohio measured inflammation markers associated with heart disease, cancer, and other health problems
- Less sleep also meant higher levels of inflammatory proteins in the blood

198
Q

Who was Elisabeth Kubler-Ross and what are contemporary thoughts about her stages of grief idea?

A

American doctors are skittish around seriously ill patients
1. Denial
2. Anger
3. Bargaining
4. Depression
5. Acceptance

199
Q

“dos” and “don’ts” for providing support to a grieving friend. What does the author suggest we avoid, and what does she suggest we do?

A

Do:
Give a supporting role
Stay present, state the truth
Be willing to witness unbearable pain
Do recurring things
Be reliable
Tackle projects together
Run interference ⇒ gatekeeper
Follow their lead
educate/advocate
Love
Dont:
Don’t take a central role
Don’t talk about futuristic or omniscient things
Don’t try to fix it
Don’t make it about you
Anticipate don’t ask

200
Q

How did doctors’ end-of-life treatment preferences differ from those gathered from non-medical people? Why might this be? How might this affect communication and treatment between doctors and patients?

A

If doctors were more honest about how treatments actually work/quality, then patients might make a different choice
Doctors: most say no they do not want treatments
- They did want pain medication
Non-medical: most say they want everything aside from some invasive stuff
- doctors know the effectiveness of interventions ⇒ TV shows make it look like treatments are more effective than they are (75% compared to 8%)
- People don’t return to the same quality of life ⇒ people end up comatose or dead more often than not

201
Q

When facing end-of-life can you expect your doctor to know how to guide you through important questions and decisions? What is a palliative care specialist?

A
  • The patient should take the lead with the suggestions of the doctors
  • Your doctor may not feel comfortable doing it, but some doctors are ⇒ the doctor should tell you to get ready and do all that you can to prepare for the end by spending time with them

Palliative care specialist: tries to provide relief and comfort depending on the patients needs and stress from symptoms, pain, and anxiety after serious illnesses have occurred
- Palliative care can be at any time whereas hospice is when there is 6 months or less left to live

202
Q

What are the 6 components experts recommend as part of the conversation about end-of-life?

A
  1. Start the conversation ⇒ the patient and their family should have the conversation amongst themselves before something goes wrong
    2.Understand your situation ⇒ know the trajectory
  2. Determine what matters the most to you ⇒ spend more time doing these things
  3. Express fears ⇒ lets doctors offer advice
  4. Discuss limits and trade offs ⇒ some care doesn’t improve quality of life
  5. Consider if hospice care is right for you