Exam 1 Flashcards
Define anatomy.
The study of the parts of the body and how they relate to each other
Define physiology.
The study of the function of the body parts.
What is the directional term for above?
Superior.
What is the directional term for below?
Inferior.
What is the directional term for “toward or at the front of the body?”
Ventral; anterior
What is the directional term for “toward or at the back of the body?”
Dorsal; posterior
What is the directional term for “toward or at the midline of the body; on the inner side of?”
Medial.
What is the directional term for “away from the midline of the body; on the outer side of?”
Lateral
Between a more medial and a more lateral structure
Intermediate
Name the floor criteria of anatomical position.
Body erect, feet slightly apart, palms facing forward, thumbs pointing away from the body.
Which body plane is a vertical cut that divides the body into anterior and posterior parts?
Frontal (Coronal) Plane
Which body plane is a vertical cut that divides the body into right and left parts?
Sagittal plane.
What is the difference between a midsagittal plane and a parasagittal plane?
Midsagittal: a sagittal cut exactly on midline, equal right and left parts
Parasagittal: sagittal cut not on the midline, unequal right and left parts.
Which body plane is a horizontal cut that divides the body into superior and inferior parts?
Transverse plane
Name the two body cavities.
Dorsal and ventral.
What cavities are in the dorsal body cavity?
Cranial cavity (brain) and vertebral cavity (spinal cord)
What cavities are in the ventral body cavity?
Thoracic (heart and lungs) and abdomino (digestive)– pelvic (urinary, reproductive)
Name the membrane that surrounds the organs in the dorsal body cavity.
Meninges
Name the membrane that surrounds the organs of the ventral body cavity.
serous membrane

Nasal

Orbital (eye)

Cervical (neck)

Frontal (forehead)

Buccal (cheek)

Mental (chin)

Sternal (breastbone/sternum)

Thoracic (chest)

Mammary (breast)

Umbilical

Coxal (hip)

Inguinal (groin)

Femoral (thigh)

Fibular, or peroneal (side of leg)

Hallux (Great toe)

Oral (mouth)

Cervical (neck)

Acromial (point of shoulder)

Axillary (armpit)

Abdominal

Brachial (arm)

Antecubittal (front of elbow)

Pelvic

Carpal (wrist)

Pollex (Thumb)

Palmar (Palm)

Digital (fingers)

Pubic (genittal region)

Patellar (anterior knee)

Pedal (foot); Tarsal (ankle)

Pedal (foot); Digital (toes)

Antebrachial (forearm)

Otic (ear)

Occipital (back of head or base of skull)

Acromial (point of shoulder)

Vertebral (spinal column)

Scapular (shoulder blade)

Brachial (arm)

Dorsum or dorsal (back)

Olecranal (back of elbow)

Lumbar (loin)

Sacral (between hips)

Gluteal (Buttock)

Perineal (region bettween anus and external genitalia)

Femoral (thigh)

Popliteal (back of knee)

Sural (calf)

Calcaneal (heel)

Plantar (sole)

Cephalic (head)

Upper extermity

Manus (hand)

Lower extremity
Name some advantages of compartmentalization.
- Membrane surrounds each organ to physically isolate organs in the same body cavity.
- Membranes hold each organ in its correct anatomical position.
- Functional isolation of each organ – neighboring organs do not interfere with the functioning of each other even when located in the same body cavity.
- Protection against the spread of infection – pathogens infecting one organ will not easily infect neighboring organs

right hypochondriac region

Epigastric region

Left hypchondriac region

Right lumbar region

Umbilical region

Left lumbar region

Right iliac (inguinal) region

Hypogastric (pubic) region

Left iliac (inguinal) region
List the levels of structural organization from smallest to largest.
Chemical, Cellular, Tissue, Organ, Organ System, Organism
Define homeostasis.
Maintenance of relatively stable internal conditions even though the internal and external environments are changing
Explain the difference between positive and negative feedback loops.
A positive feedback is when a body deviates from the norm and increases the
original stimulus. A negative feedback is when the body deviates from its normal
range and works to reduce the original stimulus by working against it.
T/F: All 11 organ systems are required to maintain homeostasis.
F; reproductive system is not involced in maintaining homeostasis.
List the levels of structural organization from smallest to largest.
Chemical → Cellular → Tissue → Organ → Organ System → Organismal
List the chemical bonds in order from weakest to strtongest
Hydrogen bonds < Ionic bonds < Polar covalent bonds < Nonpolar covalent bonds
What is the ideal blood pH level?
7.35-7.45
How do buffer systems work?
When pH is high, H+ is released by chemicals that resist abrupt changes in pH. When pH is low, H+ is bound to increase the pH.
Why are buffer systems useful?
They help our body maintain homeostasis
What is the difference between organic and inorganic compounds?
Organic compounds contain carbon chains that are covalently bound, while inorganic compounds do not have carbon.
What is the general formula for monosaccharides? Name an example.
(CH2O)n; Hexose → (CH2O)6→ glucose, fructose, galactose
What are the disaccharides maltose, sucrose, and lactose composed of?
Maltose → Glucose + Glucose
Sucrose → Glucose + Fructose
Lactose → Glucose + Galactose
What is the storage form of glucose?
Glycogen
T/F Lipids are hydrophilic substances that are soluble in water
F; They are hydrophobic and insoluble in water.
What is the universal solvent? Why is it labeled this?
Water; all biochemical reactions in the body need water
What is a salt and how does it act in the presence of water?
fsdfWhat is a?
Salts are ionic compounds that dissociate in the presence of water.
What are the 4 types of lipids?
Neutral, Phospholipid, Steroids, Eicosanoids
What are eicosanoids derived from?
Arachidonic acids
What are steroids derived from?
Cholesterol
What are phospholipids composed of?
a glycerol backbone, 2 free fatty acid chains and a phosphorus containing group
What are neutral fats composed of?
glycerol backbone and 3 fatty acid chains
What type of neutral fats are liquids at room temp and solid at room temp?
Saturated → solid
Unsaturated → liquids
What type of fat has a double bond?
Unsaturated
What is known as bad cholesterol?
LDL
Saturated fats increase LDL which increases risk of __.
MI and stroke
What terminal of amino acid acts as base? Acid?
Amino terminal → base
Carboxyl terminal → acid
What are the 2 types of secondary structures?
Alpha Helix; Beta Pleated Sheet
Fibrous proteins are known as ___ proteins. Globular proteins are known as ___ proteins.
structural; functional
What is the role of cholesterol in the plasma membrane?
To stabilize the plasma membrane
What are the types of membrane proteins?
- Integral proteins: span the plasma membrane and exposed on at least one side of the membrane; if spans both sides → transmembrane proteins
- peripheral proteins → atttached to extracellular surface of integral proteins
What are some functions of membrane proteins?
- Transport
- intercellular joining
- enzymatic activity
- cell-cell recognition
- receptors for signal transduction
- attachment to cytoskeleton
What are the three types of junctions in the membrane?
- Tight junction
- Desmosome
- Gap Junction
What are tight junctions?
fusion of integral proteins in plasma membrane of adjacent cells that
prevent the transfer of substances directly between adjacent cells hence, tight junctions
are also known as “impermeable junctions”een adjacent cells hence, tight junctions
are also known as “impermeable junctions”
What are desmosomes?
linker proteins extending from plaques on the cytoplasmic surface of the
plasma membrane of adjacent cells connected together to hold the cells together and
prevent their separation. Desmosomes are also known as “anchoring junctions”
What are gap junctions?
formed by hollow cylinders called connexon; it allows for the rapid
transfer of ions between cells; gap junctions are also known as “communication
junctions.” Cells connected by gap junctions are electrically coupled.
What are the two types of passive transport?
Diffusion (simple,facilitated, osmosis)→ substances going from high to low concentration and filtration → solutions moving from high pressure to lower pressure.
What are the two types of active transport?
active transport (solute pumping) and vesicular transport (bulk transport)
what are the types of vesicular transport?
phagocytosis, pinocytosis, receptor-mediated endocytosis
“Power plant” of the cell
mitochondria
“membrane factories” of the cell
Rough ER; membrane proteins are synthesized here before becoming part of the plasma membrane
“Traffic director” of the cell
Golgi apparatus
“demolition crew” of the cell
lysosome
What are the non-membranous cytoplasmic organelles?
Ribosomes and cytoskeleton
Name and describe the two types of ribosomes.
Free ribsomes → float in cytoplasm and make proteins that stay in cell
bound ribosomes → bound to rough ER, make proteins that go to GOlgi for packaging
What is the function of the smooth ER?
synthesis of fats, cholesterol, steroid receptors. also detoxification of drugs and carcinogens
Where in the golgi are proteins delivered and where are they released?
delivered to cid face, released from trans face
name the three types of vesicles that are released from the Golgi.
- secretory vesicles which contain proteins
- vesicles containing integral proteins and lipids that go to the plasma membrane
- lysosomes
Whatt are the three components of cytoskeleton?
Microtubules, intermediate filaments, microfilaments
What is the function of microtubules?
serve as tracks for vesicles; vesicular trafficking
what is the difference between cilia and flagellum?
Cilia → beat to move substances across the surface of cells (like moving mucus away from lung). Cilia are cellular extensions that occur in large numbers on the apical surface of cells
Flagellum → beat to move the cell it is attached to (sperm the only example). Flagellum is a singular, long cellular extension (sperm tail)
Which cytoskeleton structure provides tensile strength by resisting pulling forces
intermediate filaments
Which cytoskeleton structure is present in cells connected via desmosomes?
intermediate filaments
The arrangement of ___ is unique to each cell.
microfilamentts
Which type of cytoskeleton is involved in cytokinesis?
microfilaments
What are the 3 main regions of the nucleus?
- Nuclear envelope
- nucleolus
- chromatin
How is the nuclear envelope different from the plasma membrane?
No glycocalyx; nuclear pores present that allow molecules to enter/exit the nucleus
What does the nucleolus assemble?
ribosomal RNA; to create the 2 ribosomal subunits
What is prominent in cells producing large amounts of proteins?
nucleoli since they synthesize ribosomal subunits.
What is chromatin composed of?
DNA and histone proteins
what is the structural unit of chromtin?
nucleosomes
What are the differences between DNA and RNA
DNA → deoxyribose, double stranded, thymine, found only in nucleus
RNA → ribose, single stranded, uracil, found in nucleus and cytoplasm
Name the codon and anticodon for the triplets: AGT, TTC, CGA
Codons: UCA, AAG, GCU
Anticodons: AGU, UUC, CGA
List the phases of the cell cycle in sequential order.
G1 → S → G2 → M
What tis the longest phase of the cell cycle?
G1; growth
What happens in the S phase?
DNA replication
What happens in the G2 phase?
protein synthesis to initiate and maintain mitosis
What are the 2 phases of cell division?
Mitosis and cytokinesis
What processes exhibit saturation and specifcity?
Facilitated diffusion; active transport; receptor-mediated endocytosis
Which organelles would be abundant in a mettabolically/aerobically active cell?
Mitochondria and Peroxisomes
what do peroxisomes do?
Break down harmful free radicals
Which organelles would be prominent in a protetin-secreting cell?
Ribosomes, rough ER, Golgi
Which organelle would be abundant in a cell involved in drug detox and steroid hormone synthesis?
smooth ER
Which organelles would be prominent in a phagocyte?
ribosomes, rough ER, Golgi
What is hyperplasia?
growth by increase in cell number via mitosis
What is hypertrophy?
Growth by increase in Cell size
What is neoplasm?
abnormal and excessive proliferation of cells (can be benign or malignant)
What are the 4 primary tissues in the human body? Name their functions.
- Epithelial → Covering
- Connective → Support
- Muscle → Movement
- Nervous → Control
What are the 2 main classes of epithelial tissues
membranous epithelia and glandular epithelia
List the 4 types of simple epithelia.
- simple squamous
- simple cuboidal
- simple columnar
- pseudostratified columnar
List the 4 types of stratified epithelia.
- stratified squamous
- stratified cuboidal
- stratified columnar
- transitional epithelium
Describe the composition and location of the endothelium.
Composed of simple squamous epithelium; lines the heart and blood vessels. Also, lymphatic vessels.
Describe the composition and location of the mesothelium.
composed of simple squamous epithelium; lines the ventral body cavity.
Describe the composition and location of the respiratory epithelium.
Pseudostratified columnar; lines the upper respiratory tract
Describe the composition and location of transitional epithelium.
bladder, ureters
What are the 2 main types of glandular epithelia?
Exocrine; secrete products onto body’s surfaces and endocrine glands: secrete hormones into extracellular fluid.
What are the two types of multicellular exocrine glands?
Simple (unbranched ducts) and compound (branched ducts)
List and describe the 3 modes of secretion.
- Apocrine: apex of secretory cell pinches off to release products
- Merocrine: exocytosis used to release products
- Holocrine: secretory cell ruptures to release its contents.
What are the 4 types of connective tissue?
- connective tissue proper, cartilage, bone, blood
Match each cell in its immature form to its respective connective tissue: fibroblast, chondroblast, osteoblast, hematopoietic
Fibroblast: connective tissue proper
chondroblast: cartilage
osteoblast: osseous (bone)
hematopoietic: blood