EX2; Periodontium - PDL and Alveolar Bone Flashcards
This is a soft connective tissue between the cementum and the bony wall of the tooth socket
PDL
What are the major components of the PDL
its large highly organized bundles of collagen fibers that have their ends embedded in the cementum and bone
What is the critical function of the PDL
attachment of the tooth to the bone
What is the thickness of the PDL
.2-.4; very thin and thins with age
What are the cells of the PDL
fibroblasts; most numerous cementoblasts osteoblasts osteoclasts Epithelial rests of Mallaez immune cells undifferentiated mesenchymal (stem) cells
These are large cells that secrete and degrade collagen, and are highly active (a measure of size)
fibroblasts
What type of cell-cell junctions do the fibroblasts contain
desmosomes
gap junctions; synchronize collagen secretion
cell-ECM junctions
This is one type of cell-ECM junction; fibronectin forms part of this junction
fibronexus
The cell-ECM junction is the functional link between what
occlusal forces and fibroblasts
allowing the fibroblast to react to those forces (including, secreting and degrading collagen, etc.)
The cell-ECM junction helps to maintain orientation of what
fibroblasts in PDL thus affecting orientation of collagen fiber bundles
The cell-ECM junction has links to what component
the actin skeleton and ultimately interacts with the collagen in the ECM
Where would you find the cementoblasts, osetoblasts, and osteoclasts in the PDL
near the tissue they are involved with
cementoblasts = cementum
osteoclast/blast = bone
What distinguished osteoclasts from the other adjacent cells
multiple nuclei
When would resorption of the cementum occur
in special situations like shedding of deciduous dentition or trauma
although small regions of cementum respiration is not unusual
These are remnants of HERS present in the PDL, lying closer to the cementum in clusters
Epithelial rests of Mallasez
What is the function of the Epithelial rests of Mallasez
unknown function; but an proliferate and form cysts
These cells lie close to the blood vessels and give rise to new cells, and contribute to maintaining the viability of the periodontium
undifferentiated mesenchymal cells (stem)
What are the fibers of the ECM of the PDL
collagen types I (80) and III (20) (also XII)
oxytalin
What are the ground substances of the ECM of the PDL; important in withstanding compressive loads
PGs and assocaited GAGs (water retention)
glycoproteins = fibronectin
Collagen forms what percentage of the PDL
47-52%