Evidence Synthesis Flashcards

1
Q

what is a narrative review most useful for?

A

obtaining a broad perspective on a topi

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2
Q

what is a narrative review?

A

An account of what has been published on a topic by accredited scholars &
researchers

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3
Q

what are the steps to doing a narrative review?

A

review question formulation

searching for relevant studies

deciding which studies to include and exclude

assessing study quality

synthesizing study

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4
Q

what is a thesis literature review?

A

Identify areas of prior research

Place your original work in the context of existing literature

Describe the relation of each work to the others under consideration

Identify new ways to interpret previous research

Resolve conflicts amongst seemingly contradictory previous studies

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5
Q

what is the purpose of a scoping review?

A

to map out and summarize existing literature on a broad topic area. It aims to provide an overview of the available evidence, identify key concepts, themes, and gaps in knowledge, and clarify the scope of future research.

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6
Q

what type of research question does a scoping review address?

A

exploratory

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7
Q

what are the steps to a scoping review?

A

Identifying the research question

Identifying the relevant studies

Study selection

Charting the data

Collating, summarizing and reporting the result

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8
Q

what is a systematic review?

A

a rigorous and comprehensive method of summarizing and synthesizing existing evidence on a specific research question or topic. It involves systematically searching, selecting, appraising, and synthesizing relevant studies to provide an unbiased and transparent summary of the available evidence.

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9
Q

Why do we need to conduct a systematic
review?

A

Conflicting evidence

To determine the best practice

To explore the relationship between an exposure and an outcome

Variation in behavior (clinicians; patients)

To identify research gaps

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10
Q

what do systematic reviews provide the evidence base for?

A

Clinical practice guidelines

Health technology assessment tools

Policy briefs

Patient decision aids

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11
Q

what is Standardized mean difference (SMD)

A

Summary statistic when studies all assess the same outcome but
measure it different ways ( all studies measures anxiety but use
different outcome measures)

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12
Q

what is a meta analysis?

A

a combination of at least 2 studies to produce a
single estimate of the effect of a heath care intervention under
investigatio

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13
Q

what is heterogeneity?

A

the variability or diversity among the participants, interventions, outcomes, or study designs in a group of studies being analyzed. It indicates differences between the individual studies that are being synthesized or compared.

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14
Q

what is publication bias?

A

Studies with significant results are more likely to:
* be published
* be published in English
* be cited by others
* produce multiple publications

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15
Q

why does publication bias matter?

A

Negative studies not being published leads to:
* overestimation of benefit and
* underestimation of harm

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16
Q

what guidelines do we use for meta analysis of RCTs?

A

PRISMA statement

17
Q

what guidelines do we use for meta analysis of observational studies?

A

MOOSE guidelines

18
Q

approx how much time does it take to conduct a meta analysis?

A

1139 hours