everything about the cerebellum 5.4-5.5 Flashcards

1
Q

where is the cerebellum located

A

posterior cranial fossa

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2
Q

what is the white matter of the cerebellum called

A

arbor vitae, with folds called folia

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3
Q

what is the falx cerebelli

A

separates the two hermispheres

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4
Q

what is the tentorium cerebelli

A

separates the cerebellum from the cerebrum

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5
Q

what is the primary fissure of the cerebellum

A

separates the anterior and posterior lobe

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6
Q

what i the postero-lateral fissure

A

separates the posterior and floculonodular lobe

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7
Q

what are the three lobes of the cerebellum

A

anterior
posterior
flocculonodular

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8
Q

what are the four deep nuclei of the cerebellum

A

Dentate
Emboliform
Globose
Fastigial

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9
Q

what are the 3 cerebellar peduncules

A

superior
middle
inferior

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10
Q

what are the three layers of the cerebellar cortex

A
  1. molecular layer
  2. purkinje layer
  3. granule layer
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11
Q

what is in the molecular layer 2 key, 4 total

A

two inhibitory neurons: stellate and basket cells
axons of granule cell
dendrites of purkinje fibres

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12
Q

what is in the purkinje layer

A

purkinje cells

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13
Q

what is the granule cell layer

A

granule cells
a third inhibitory - golgi cell

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14
Q

role of the dentate nucleus 2

A

biggest

receives projections from lateral cerebellum

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15
Q

role of emboliform and glibose nucleus

A

receives projections from intermediate cerebellum

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16
Q

role of fastigial nucleus 2

A

receives input from the vermis and flocculonodular lobe

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17
Q

what are the two structures which are the source of synaptic input

A

mossy fibres
climbing fibres

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18
Q

role of mossy fibres 5 steps

A

ascend through cerebellar and synapse on granule cells

granule cells go to molecular layer and bifurcate becoming parallel fibres

each parallel fibre innervates multiple purkinje fibres

purkinje cell axons then carry inhbibitory output to cerebellar nuclei

then taken to the cerebrum

19
Q

role of climbing fibres 4

A

arise from contralateral olivary nucleus

wrap around purkinje cells in 1:1 ratio forming exictatory ynapses

decrease purkinje cells respne to inputs from parallel fibres

therefore, modulate purkinje cell activity

20
Q

function of basket and stellate cells 2

A

inhibit adjacent purkinje cells through lateral inhibition

narrows spatial extent of excitatory inputs to purkinje cells

21
Q

function of golgi cells 2

A

provide feedback inhibition to granule cells

shorten the time duration of excitatory inputs to granule cells

22
Q

cerebellar input

A

receive information from the cerebrum via the inferior, middle and superior cerebellar peduncles

mossy and climbing fibres receive these stimuli and travel to the cerebellar cortex to activate pathways

23
Q

function of the anterior lobe 2

A

regulation of muscle tone

coordination of voluntary movements

24
Q

function of posterior lobe 2

A

intergration of sensory input and coordination of fine motoe movements

25
flocculonodular lobe function 3
balance control spatial orientation eye movement
26
cerebellar output pathway for motor planning 5
lateral cerebellar hemisphere dentate nucleus superior cerebellar peduncle VL of thalamus cortex projections
26
cerebellar output pathway for movement of the extremities 5
intermediate cerebellar hemisphere emboliform +globose nuclei superior cerebellar peduncle VL of thalamus and red nucleus Cortical projections and lateral corticospinal tract
27
cerebellar ouput pathway for proximal trunk and vestibulo-ocular control 4
vermis and flocculonodular lobe vestibular and fastigial nucleus superior and inferior cerebellar peduncles cortex
28
functional divisions of the cerebellum 3
vestibulocerebellum spinocerebellum cerebrocerebellum
29
functional divisions and their associated hemisphere
vestibulocerebellum = flocculonodular lobe cerebrocerebellum = posterior lobe spinocerebellum = anterior, vermis and posterior lobe
30
impairment to vestibulocerebellum results in 2
difficulty maintaining balance coordinating movements
31
impairment to cerebrocerebellum results in
delay in initiating movement
32
impairement in spinocerebellum results in 2
decreased accuracy in actions poorly coordinated movement
33
lateral vs medial lesions in the cerebellum
lateral lesions affect distal limb coordination medial lesion affect trunk, posture, gait and balance
34
truncal ataxia 2
midline lesion of vermis/flocculonodular lobe wide unsteady drunken gate
35
appendicular ataxia
lesions lateral to vermis
36
dysdiadochockinesia
inability to perform rapid alternating movements
37
what lesion results in dysdiadochockinesia
vermis
38
nystagmus lesion location
vestibulocerebellum
39
intention tremor
tremour during movement
40
lesion localisation of intention tremour
cerebellar hemisphere
41
hypotonia
reduced muscle tone
42
astasia
inability to walk due to lack of coordination of joints
43
abasia
inability to stand due to inability to stand upright against gravity