1.7 neural development

Question 1

from whcih germinal layer does the nervous system develop from

Answer 1

ectoderm

Question 2

process of nervous system formation 5 steps

Answer 2

1. neuroectoderm thickens into neural plate
2. edges of plate curve forming neural groove
3. neural folds fuse together forming neural tube
4. 3 primary vesicles develop
5. tube completely closes

Question 3

what are the three primary vesicles

Answer 3

prosencephalon
mesencephalon
rhombocephalon

Question 4

neuropores

Answer 4

openings at either end of neural tube which allow free communication with amniotic fluid

Question 5

what does the pro-encephalon split into

Answer 5

diencephalon and telencephalon

Question 6

what does the rhombocephalon split into

Answer 6

metencephalon and myelencephalon

Question 7

three flexures involved in neural development

Answer 7

cephalic flexure - persists till adulthood, bend between brainstem and cerebrum
cervical flexure
pontine flexure

Question 8

what is dorsal ventral patterning 3

Answer 8

in dorsal region of neural tube release of bone morphogenetic proteins

in ventral region of neural tube release of sonic hedgehog protein

leads areas to develop differently, will result in formation of dorsal and ventral parts of the spinal cord

Question 9

what are the name of the plates associated with the development of dorsal and ventral parts of the spinal cord

Answer 9

alar plate = dorsal horn of sc

basal plate = ventral horn of sc

Question 10

where are bone morphogenetic proteins released

Answer 10

dorsal part of neural tube

cause differentiation of dorsal part of sc

Question 11

where are sonic hedgehog proteins released

Answer 11

ventral part of neural tube, specifcally notochord

cause differentiation of ventral part of sc