Evaluation and Nonsurgical Management of Benign Prostatic Hyperplasia Flashcards

1
Q

BPH is characterized by an increased ___ of epithelial and stromal cells.

2.

A

NUMBER

NOT SIZE!

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2
Q

__ are required for normal cell proliferation and differentiation and actively inhibit cell death.

A

Androgens

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3
Q

Early periurethral nodules are__; transition zone proliferation is __

A

stromal,glandular

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4
Q

Prostatic stroma represents __ of the gland. __ muscle is a prominent component of the stroma.

A

40% of the gland.

SMOOTH Muscle

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5
Q

Symptoms that use the AUA Symptom Index are classified as mild if the score is ___, moderate if it is __, and severe if it is __. A change of __ points or more from time to time is subjectively discernible

A

0-7

8-19

20-35

3

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6
Q

Bladder__ is seen in both sexes with advancing age.

A

FIBROSIS

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7
Q

. A significant portion of male lower urinary tract symptoms is related to ___ and other conditions unrelated to the prostate.

A

age-related detrusor dysfunction

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8
Q

DHT, the ___androgen in the prostate, and androgen receptors ___ remain with age.

A

most potent

high

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9
Q
  1. Androgen withdrawal results in __ of prostate cells.
A

apoptosis

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10
Q

__ receptors are found in the prostate and may play a role in BPH.

A

Estrogen

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11
Q

The size of the prostate does/does not correlate with the degree of obstruction.

A

does not correlate!

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12
Q

Trabeculation is due to an increase in :

A

detrusor collagen.

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13
Q

A maximum flow rate __ in the male indicates a high probability of obstruction.

A

less than 10 mL/sec

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14
Q

There is no/there is a relationship between vasectomy and BPH; however, there is/there is no positive relationship between lack of physical activity, obesity, BMI, and LUTS/BPH. 1

A

THERE IS RELATIONSHIP BETWEEN VASECTOMY AND BPH

THeRE IS A POSiTIVE RELATIONSHIP

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15
Q

familial BPH tend to have__ glands than those with sporadic BPH.

A

LARGER

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16
Q

Cold medications containing ___ tend to exacerbate lower urinary tract symptoms by the expected effect on the smooth muscle of the bladder outlet

A

α-sympathomimetics

17
Q

clinically useful correlation exists between total and ___ zone prostate volume and serum PSA in men with BPH

A

TRANSITION ZONE