Essential Pharmacology Flashcards
Receptor enter cells when they are?
lipid soluble
What are the 4 types of cell-membrane receptors?
Iontropic
receptor that acts as an enzyme
receptor that changes activity of another enzyme
G-protein receptor
Receptors can be..
Intracellular or membranous
What does efficacy mean?
How good the drug is at activating the receptor
What is the difference between affinity and efficacy?
Affinity is does the drug bind to the receptor
Efficacy is how well it binds to the receptor
What is an agonist?
A drug/ substance that activates a receptor
Has high efficacy and high affinity
What is an antagonist?
A drug/ substance that blocks the normal action of a receptor.
Has high affinity and low efficacy
What is a partial agonist?
Has high affinity and partial efficacy.
Why is acetyl choline special?
agonist that activates all cholinergic receptors.
Master key.
What does noradrenaline do?
agonist that activates all adrenergic receptors.
Why are antagonists also good?
Can block ‘bad’ effects.
