Esophageal disorders Flashcards
Caused by backflow of gastric acid and contents into the esophagus
GERD
Barrier incompetence
Anti-cholinergics B-adrenergics Aminophylline Nitrates Calcium channel blockers
CMV infxn tx
Gancyclovir
Most common esophageal diverticulum
Zenker’s diverticulum
Diverticulum in posterior hypopharyngeal wall
Zenker’s diverticulum
Bird’s beak
Achalasia
Esophageal body loses peristaltic contractions
Achalasia
LES does not relax
Achalasia
Loss of intramural neurons
Achalasia
Metaplasia
Barretts esophagus
Viral
HSV
VZV
CMV
Immunocompromised
Candida
Eosinophilic invasion
Eotaxin-3
Drug-induced cardiomyopathy
Doxurubicin
Hemorrhagic cystitis
Cyclophosphamide
Nephrotoxicity
Ototoxicity
Perioheral neuropathy
Cisplatin
Corrosive that is more dangerous because of deeper penetration
Alkali
Pill-induced esophagitis
NSAIDs
KCL
FeSO4
Tetracyclines
Most common site of zenker’s diverticulum and perforation
Killian’s triangle
Hypopharyngeal webs
Iron deficiency anemia
Atrophic Glossitis
Plummer-vinson syndrome
Ring in Lower esophageal ring
Schatzki ring
Spontaneous rupture from forceful retching
Boerhaave’s syndrome
Linear mucosal tear near GEJ assoc with retching or vomiting and alcoholics
Mallory-weiss syndrome
Most common site of Mallory-weiss tear
GEJ
Portal HPN
Esophageal varices
Pre-sinusoidal obstruction
Schistosomiasis
Post-sinusoidal obstruction
Budd-chiari syndrome
Hepatic vein thrombosis
Ascitis
Budd-chiari syndrome
Best method for dx and active bleeding tear
Endoscopy
H.pylori
Peptic ulcer disease
Urease producing organism
H.pylori
Block prostaglandin synthesis, impairing mucosal defense and repair
NSAIDs
Most common cause of UGIB
PUD
PUD causes
H.pylori
NSAIDs
Burning epigastric pain exacerbated by fasting improved with meals
PUD
Unclean food Unclean water Poor education Exposure Sanitation Economic status
Risk factors of PUD
Associated with malignancy
Gastric ulcer
Pain precipitated by intake of food
Gastric ulcer
Pain occurs 1.5 H after meal, relieved by antacids or food
Duodenal ulcer
Pain wakes patient at night 12mn- 3am
Duodenal ulcer
Punched out defect
Duodenal ulcer
Heaped up margins
Gastric ulcer
Portion of duodenal ulcer located
First portion of duodenum
Located w/n 3cm of pylorus
Duodenal ulcer
Ranitidine
Famotidine
H2 receptor antagonist
Recommended tx for PUD
PPI
Omeprazole
Esomeprazole
Cryoprotective agents
Sucralfate
Bismuth citrate
Bismuth side effect
Black colored stool
Misoprostol
PGE-1
Combination therapy
H.pylori eradication
PPI
AMOXICILLIN
CLARITHROMYCIN