Esophageal Ca. Flashcards

Stem; A male patient heavy smoker and alcoholic with dysphagia , history of GERD and severe weight loss in a short time.

1
Q

Q1: What is the normal esophagus lining ?

A

Non-Keratinized Stratified Sq. Ep.

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2
Q

Q2: What is the most probable diagnosis ?

A

Esphogeal Ca.

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3
Q

Q3. What are the etiological factors of cancer esophagus in this patient ?

A

Alcoholic / Smoker / GERD

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4
Q

Q4. What is the effect of prolonged GERD?

A

Chronic irritation – > MEtaplesia – > barret’s esophagus – > Adenocracinoma

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5
Q

Q5. Which test you would like to do for this patient ?

A

Esophageal endocopy / EUS +Take biopsy / FNAC

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6
Q

Q6: What the obtained cells will tell you ?

A

Stage / Grade / IHC

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7
Q

Q7.What is the stain used in IHC ?

A

Cytokeratin

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8
Q

Q8: What are the treatment options for esophageal cancer?

A

If operable
* Esophagectomy + radiotherapy (Ivor Lewis Esophagectomy or Mckeown esophagogastrectomy)
If non-operable
* Debulking
* Self-expanding metallic stent
* Palliative chemo & radiotherapy
* Feeding jejunostomy

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9
Q

Q9. if patient develops pleural effusion, What are the possible causes ?

A

Spread to pleaura / Mets to lung / Obstruction of Thoracic duct / Nutritional

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10
Q

Q10. What pathological test to do ?

A

Effusion – > cytology / Gram staining / microbiology of culture

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11
Q

Q11: How to treat ?

A

Thoracocentesis / Indw Pl. Cath / Pleaurodesis / Pleuroperitoneal shunt

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12
Q

Q12: The patient developed enlarged supraclavicular lymph node , what will you do ?

A

FNAC

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13
Q

Q13: Investigations of MI?

A

Labs; Troponin levels – CKMB Levels
ECG / ECHO

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14
Q

Q14: what Is troponin ?

A

Complex of 3 regulatory ptns (C,I,T) that’s integral to ms contraction

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15
Q

Q15: where is it found ?

A

Cardiac and Skeletal Ms

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