Erythropoiesis

Question 1

acronym CFU-GEMM

Answer 1

Colony-Forming Unit Granulocyte Erythrocyte Monocyte/Macrophage Megakaryocte

Question 2

rise to the earliest identifiable colony of RBCs

Answer 2

CFU-GEMM

Question 3

earliest erythroid progeniitor, or earliest identifiable colony of RBCs

Answer 3

Burst-forming Eythroid

Question 4

• glycoprotein by kidney & liver that induces Hb synthesis & differentiation factor
• release reticulocytes from BM vary
• inhibition of apotosis
• redeuce marrow transit time

Answer 4

erythropoietin

Question 5

is the stimulus that activates production & secretion of EPO

Answer 5

Oxygen availability

Question 6

earliest visually recognized erythrocyte precursor in the bone marrow
-has many EPO receptors

Answer 6

Colony-forming unit erythroid

Question 7

terms sometimes associated to the reticulocyte specially when see on the PBS

Answer 7

diffusely basophilic erythrocyte & polychromatophic erythrocyte

Question 8

acronym PBS

Answer 8

Peripheral Blood Smear

Question 9

• anucleate

- no protein or Hb sysnthesis

Answer 9

Mature Erythrocyte

Question 10

life span of erythrocyte

Answer 10

120 days

Question 11

resting state of erythrocyte

Answer 11

biconcave disc or discocyte

Question 12

size in thickness of erythrocyte

Answer 12

1.5 um to 2.5 um

Question 13

size in diameter of erythrocyte

Answer 13

7.8 um

Question 14

peripheral blood smear staining for erythrocyte

Answer 14

salmon pink-staining cell w. a central pale area

Question 15

size of the RBC=

Answer 15

corresponds to disease