erectile dysfunction Flashcards
wha is the neurotransmitter responsible for initiating and sustaining and erection?
nitric oxide
what is a key messenger in the erection prociess?
cyclic GMP, broken down by PDE
how do you diagnose psychogenic ED?
+ nocturnal/morning erections
how can you tell if you have organic ED?
no nocturnal erection
definition of erectile dysfunction?
inability to attain or maintain
what can cause organic ED?
marijuana, alcohol, tobacco
what disease can lead to erectile dysfunction that we learned about?
peyronies
what test can be used to differentiate between organic and psychogenic ED?
nocturnal penile tumescence testing
how can you rule out vascular system as the cause for ED?
trial of PDE-5 inhibitors or injections of vasocactive substances PGE1)
what additional vascualr tests may be used if a person fails the vasoactive injection tests?
duplex doppler u/s
penile cavernosography
pudendal arteriography
what do you have to worry about w/ PDE-5 inhibitors?
hypotension w/ patiens on alpha blockers for lower urinary tract symptoms
what medications contraindicate the use of PDE-5 inhibitors?
nitro and nitrates
how long before sex do you have to take sildenafil and vardenafil?
1 hr before sex effective up to 4 hours
what is tadalafil good for?
BPH w/ ED onset w/in 30-60 min lasts 36 hrs
what can be taken 15 min before sex?
avanafil