deck 6 Flashcards
PP ON THIS: DDX for hematuria
period, prostate, papillary necrosis, obstructive, nephritic, trauma, tumor, TB, thrombosis, hematologic, infection, stones
ATN, toxic injury, drug-induced interstitial nephritis, and hereditary metabolic disorders (wilson and fanconi) are what type of proteinuria?
tubular: faulty reabsorption of normally filtered proteins
an old person w/ hx of smoking presenting with painless hematuria has what until proven otherwise?
bladder cancer
what is the goal of treatment for proteinuria?
lower
imaging for hematuria?
CT urogram, cystoscopy- urology referral
diabetic nephropathy is caused by what kind of proteinuria?
glomerular proteinuria: thinning of the cell foot processes and altered glomerular permeability
what is considered microalbuminuria?
30-300 mg/day
what is the hallmark of diabetic neuropathy and indicates worsening renal function?
microabluminuria
what can you not do before a proteinura test?
exercise
acute illness, exercise, and orthostatic proteinuria are what type of proteinuria?
functional
if there is a calculi (stone), ureteral, cystic, or urethral origin who do you refer to?
urology
gross hematuria in adults is a warning sign of what in adults?
gross hematuria
causes of false positive hematuria on dipstick, but negative microscopy
hemoglobinuria (black, hemolysis), myoglobinuria (coke, rhabdo), drug: pyridium, bacteria, beets, rhubarb, concentrated urine, menses
if you have initial hematuria where is the source?
anterior (penile) urethral source
what to do if persistent unexplained hematuria?
urine cytology to rule out cancer
proteinuria is defined as what?
150 mg/24 hrs
when will protein be measured by dipstick?
> 300mg per day
what are the types of proteinuria?
glomerular
tubular
overload
functional
if you have terminal hematuria where is the source?
prostatic urethral or bladder neck
if you have total hematuria where is the source?
bladder, upper tract
if there is persistent hematuria who do you refer to?
nephrology because most likely renal parenchyma
what sample is recommended for proteinuria in diabetics?
random albumin: creatinine ratio
multiple myeloma, rhabdomyolysis, hemolysis are what kinds of proteinuria?
overload: over production of circulating filterable proteins (bence jones, hemoglobin)
what test is good for monitoring established proteinuria?
protein:creatinine ratio
what is the level for nephrotic proteinuria?
> 3.5 g/day
