Equine Reproductive Failures Flashcards
When does the highest pregnancy loss occur?
within the first 14 days
Why is there an increased pregnancy loss rate in older mares?
More likely to produce defective oocytes
Lack of oocytes reaching oviducts
What happens when early embryonic death occurs before maternal recognition of pregnancy?
Normal inter-oestrus interval
EED unsuspected
What is the suspect cause of EED?
Low P4
What is the normal growth rate of an embryo (mm/day)?
3mm/day
After how many days does the embryo fix at the base of the uterine horn?
16 days
When is heartbeat check done?
28 days
What should you do if the embryo is not progressing and does not look good after rechecking?
Abort
What vesicle size indicates that there is an abnormalilty?
Small vesicle
A continued mobility of vesicle upon ultrasound indicates what?
Abnormal development
Name the 5 things to check upon embryo assessment
- Size of vesicle
- Mobility of vesicle
- Fluid presence surrounding vesicle
- Appearance of conceptus
- Heart beat
Is fluid surrounding the vesicle normal? What does it indicate?
No. Endometrial oedema
What two things should you do if a lymphatic cyst is discovered upon ultrasound?
- Map out location
2. Determine size of cyst
Name the 3 methods of cyst ablation
- Mechanical removal
- Puncture and aspirate
- Laser therapy
What is the incidence rate of abortion?
5-15%
Abortion is the _____ of the pregnancy before the foetus is capable of _____ life
Abortion is the termination of pregnancy before the foetus is capable of extrauterine life.
What 3 infectious agents are associated with abortion storms?
- Equine herpes virus type 1
- Equine herpes virus type 3
- Mare Reproductive Failure Syndrome
What must you be careful of when handling the foetus/foetal membranes?
Infectious agents - disinfect
What are the 4 routes of transmission for Equine Herpes Virus?
- Transplacental
- Aerosol
- Nasal mucosa
- Aborted foetus
How can a mare pass EHV to her unborn foal?
Transplacental transmission
What % of abortions are caused by EHV?
10-15%
What type of EHV is associated with respiratory disease?
EHV 1
What two breeds have the highest prevalence of Equine Viral Arteritis?
Standardbreds and warmbloods
Is the mare or the stallion the carrier for Equine Viral Arteritis?
Stallion
Natural infection stimulates strong long lasting immunity in which virus?
EVA (Equine Viral Arteritis)
What insect causes Mare Reproductive Loss Syndrome?
Eastern tent caterpillar
What insect causes Equine Amnionitis and fetal loss (EAFL) in Australia?
Processionary caterpillar
Why does caterpillar ingestion cause abortions?
Exoskeleton/hairs
What bacterium is carried by birds?
Chlamydia psittaci
Taylorella equigenitalis is responsible for what disease?
Contagious equine metritis
What disease causes a shortened dioestrus in mares?
Contagious equine metritis
What are the 3 swab sites from the stallion that are used to diagnose contagious equine metritis?
- Urethra
- Urethral fossa
- Penile sheath
What are the 2 swab sites from the mare that are used to culture and diagnose contagious equine metritis?
- Clitoral fossa
2. Clitoral sinuses
Which diagnostic method for contagious equine metritis is the most reliable?
PCR
What is the incidence rate of placentitis?
3-7%
What is the most common type of placentitis?
Ascending
What are the 3 aetiologies of placentitis?
- Pathogenic
- Haematogenous
- Nocardioform
What is the normal foetal heart rate before day 160 of gestation?
160 BPM
What is the best method to diagnose twins?
Transrectal ultrasound
How many days post ovulation is an ultrasound done?
14-15 days
What 2 things do you check for in a transrectal ultrasound?
- Check ovaries
2. Count CLs
How many days post OV does fixation of the embryo occur?
16 days
Where does fixation occur?
Base of the uterine horn
What is the best method of removing an embryo pre-fixation?
Embryonic crushing
If the embryos are bilateral during post fixation phase, what is the best method of twin management up to day 35?
Embryonic crush
If the embryos are unilateral during post fixation phase, what is the best management methods up to day 35?
Recheck in a couple of days
Which breeds have the highest risk of multiple ovulations?
TB, draught horses, quarter horses and standardbreds
Mares are very efficient at reducing twins to a single pregnancy. True/False?
True
What is the most common form of twin pregnancy?
Unicornial
What is a diagnostic method used to detect foetal heart beat?
Colour doppler
What is one twin management method during post fixation that can be done prior to day 35?
Transvaginal ultrasound guided aspiration
What procedures can be done to remove a twin pregnancy after the endometrial cups form during the post fixation phase (>35 days)
Cranio-cervical dislocation
Transcutaneous foetal injection
After how many days post OV can a transcutaneous foetal injection be carried out?
> 100 days
What is the normal length of an umbilical cord?
<80cm
How many twists indicate a torsion?
> 12 twists
What are the 4 things you should first check when a mare is not cycling?
- Spring transition
- Pregnancy
- Ovarian abnormalities
- Developmental abnormalities
What is the normal karyotype in mares?
64XX
What diagnosis can be used to determine chromosomal abnormalities?
History
Physical examination
Blood sample for karyotyping
What are the signs of a granulosa cell tumors in mares?
Stallion like behaviour
Anestrus
What 3 diagnostic methods can be used to determine a GCT?
- Palpation
- US
- Hormones
What is the hallmark hormone test for granulosa cell tumor?
Anti-mullerian hormone (AMH)
What is the preferred method of resolving a granulosa cell tumor?
Surgical removal of ovary
What are the two types of anovulatory follicles?
- Hemorrhagic anovulatory follicle
2. Persistent anovulatory follicle
What does HAF stand for?
Hemorrhagic anovulatory follicle
What does PAF stand for?
Persistent anovulatory follicle
During what time of year are anovulatory follicles more persistant?
Autumn
What are 4 contributing factors to the ‘problem mare’?
- Not being able to carry a foal to term
- Know reproductive pathology
- Behavioural issues related to reproduction
- Not becoming pregnant after being bred to a fertile stallion over 3 oestrus cycles
What are the 3 most common reproductive abnormalities in a mare?
- Failure to ovulate
- Bacterial endometritis
- Persistent post mating endometritis
What are 3 contributing factors to Persistent post mating endometritis (PMIE)?
- Poor lymphatic drainage
- Poor conformation
- Poor contractions
Poor c_____, poor c_______ and poor l______ are all contributing factors to PMIE
Poor contractions, poor conformation and poor lymphatics are all contributing factors to PMIE
What are 3 ecbolic treatment methods for PMIE?
- Oxytocin
- Prostaglandin
- Uterine lavage
What 2 things should be minimised to help manage PMIE?
- Uterine contamination
2. Number of breedings
What are the 3 seals that protect the mares genital tract?
- Vulvar seal
- Vestibulovaginal seal
- Cervix
The vulvar lips should be evenly ____ and ____ orientated.
The vulvar lips should be evenly closed and vertically orientated
What fraction of the vulvar should be distal to the level of the ischial arch?
2/3
H______, S____, P____ ___ and C___ ____ should be taken into account when forming a diagnosis for a mare.
History, signs, physical exam and common pathogens should be taken into account when forming a diagnosis for a mare.
What number of neutrophils/high power field indicate active inflammation in a mare’s uterine cytology?
1-2 NTP/hpf
What number of neutrophils/high power field indicates moderate-severe inflammation?
> 5 NTP/hpf
What is the gold standard test for endometritis?
Endometrial biopsy
C___ s___, u____ e____ s____ and r___ c___ d___ are all procedures which correct the damaged physical barrier in a case of physometra.
Caslick’s surgery, urethral extension surgery and repairing cervical damage are all procedures which correct the damaged physical barrier in a case of physometra.
Name 3 disinfectants that can be used to treat endometritis.
- Iodine solution
- Acetic acid/vinegar
- Hydrogen peroxide
What disinfectant is NOT suitable for use to treat endometritis?
Chlorhexidine
What 3 chelators can be used to treat endometritis?
- EDTA-tris
- N-acetylcysteine
- DMSO solutions
What do chelators do?
Break down biofilms of pathogens
Name 3 antifungal agents that can be used to treat endometritis.
- Nystatin
- Clotrimazole
- Fluconazole