Epithelium Flashcards

1
Q

What are the two types of epithelium?

A

Surface epithelium and glandular epithelium

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2
Q

What are the functions of epithelium?

A

Protection, secretion, receptors, absorption, barrier

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3
Q

What are the characteristics of epithelium?

A

Polar (different domains), avascular, cells are connected by cell junctions, has a basement membrane

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4
Q

What are the different classifications of surface epithelium?

A

simple squamous, simple columnar, simple cuboidal, pseudostratified ciliated columnar, stratified squamous, stratified cuboidal, transitional

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5
Q

What does simple squamous epithelium look like?

A

One layer of flat cells

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6
Q

Where is simple squamous epithelium found?

A

mesothelium (lining of body cavity), endothelium (lining of heart), lining of alveoli, glomeruli

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7
Q

What does simple cuboidal epithelium look like?

A

One layer of cube like cells

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8
Q

Where is simple cuboidal epithelium found?

A

thyroid follicles, renal tubules

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9
Q

What does simple columnar epithelium look like?

A

One layer of tall (columnar) cells - can either be ciliated or non ciliated

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10
Q

Where is simple columnar epithelium found?

A

Non ciliated in stomach, intestines, gall bladder, bile ducts, endometrium, endocervix and ciliated in fallopian tubes and bronchioles

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11
Q

What does pseudostratified ciliated columnar epithelium look like?

A

It looks stratified but is actually simple (only one cell layer) because the cells are so long - but really each cell touches the basement membrane

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12
Q

Where is pseudostratified ciliated columnar epithelium found?

A

In the respiratory tract - non ciliated is found in the vas deferens and the epididymus

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13
Q

What does stratified squamous epithelium look like?

A

Only the top layer of cells are actually squamous cells - there are then several layers of cells down to the basement membrane - there are two types keratinising and non keratinising

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14
Q

Where is stratified squamous epithelium found?

A

keratinising is found in the skin, non keratinising is found in the oral cavity, oesophagus, vagina, ectocervix, anus

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15
Q

What does stratified cuboidal epithelium look like?

A

It is two layers of cuboidal cells

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16
Q

Where is stratified cuboidal epithelium found?

A

In ducts

17
Q

What does transitional epithelium look like?

A

It is stratified epithelium that looks either squamous or cuboidal depending on whether it is stretched or not

18
Q

Where is transitional epithelium found?

A

renal pelvis, ureters, bladder

19
Q

What is microvilli?

A

Tiny extensions of the apical surface on epithelial cells - to increase surface area

20
Q

What are cilia?

A

Long projections on the apical surface of some epithelium - contains microtubules - for movement

21
Q

What are the different kinds of intercellular junctions in epithelium?

A

tight junctions, adhering junctions (desmosomes) and gap junctions

22
Q

What is the purpose of tight junctions?

A

Tight junctions seals of intercellular spaces so that nothing can get through

23
Q

What is the purpose of adhering junctions?

A

To link cytoskeleton between cells - resists shearing forces

24
Q

What is the purpose of gap junctions?

A

To allow communication between cells

25
Q

What are cell adhesion molecules (CAMS)?

A

Transmembrane proteins that link with CAMS on neighbouring cells

26
Q

What are the four different types of CAMS?

A

Caherins, integrins, selectins, immunoglobulin superfamily

27
Q

What is mucosa?

A

Surface epithelium and underlying supportive connective tissue

28
Q

What is serosa?

A

Surface mesothelium and underlying supportive connective tissue

29
Q

What is erosion?

A

Defect in surface eptihelium

30
Q

What is an ulcer?

A

Local defect in mucosa

31
Q

What are goblet cells?

A

Mucus secreting single cell glandular epithelium that has an exocrine function

32
Q

What is serous acini?

A

A secretory unit of serous cells

33
Q

What are myoepithelial cells?

A

Contractile cells that surround glands

34
Q

What are the 3 components of cytoskeleton?

A

microfilaments, intermediate filaments, microtubules