Epithelial Tissues + Glands Flashcards
Where is epithelial found
Covers all external surfaces and lines internal passageways and chambers, forms glands
What does epithelial tissue include
Epithelia and glands
What are glands
Glands are structures that produce fluid secretions
They are either derived from epithelia or attached to epithelia
What is the overall functions of epithelial tissues? 4
1.physical protection
2.control permeability
3.produce specialised secretions
Common characteristics of ALL epithelial tissues
- Polarity (attached basal,lateral, exposed apical surface)
- Avascular
- cellularity (all cells bound tgt tightly with interconnections/junctions)
What is the name of the junction with the protein connexin and how many connexin make a connexon?
Gap junctions
6 connexins make a connexon
What are the specialisation of epithelia cell?
Cilia
Microvilli
Keratinized
5 types of cell junctions
Gap junctions
Adhering junctions
Tight junctions
Desmosomes
Hemidesmosomes
What are the functions of gap junctions?
Movement of ions through the gap junctions help coordinate movement like the beating of cilia , coordinate muscle controls too
Where are tight junctions located?
Encircle the apical regions of epithelial cells
What are tight junctions also known as?
Zona occludens / occluding junctions
Function of tight junctions
- prevent water and solutes from passing between the cells
- isolate contents of lumen from basolateral surfaces of the cell
- tight junctions at the apical surface of cells that line digestive tract prevent acids and enzymes from damaging the tissues underneath
What do desmosomes do and why?
Links cytoskeletons of adjacent cells to form strong cohesive epithelium. Because most epithelial cells are subject to mechinal stresses and need durable interconnections.
Desmosomes are very strong and can resist stretching and twisting
What are all the proteins involved with the different cell junctions?
Claudins, tricellulin,Occludin for tight junction
Cadherin for desmosomes
Integrin, laminins for hemidesmosomes
Cadherin for adhering belt
Connexins for gap junctions
Where in the cell is the adhering belt located
In the lateral plasma membrane, immediately below the tight junction
Where is hemidesmosomes found and what is it’s function
Found at the basal surface , using protein integrin to link epithelial to basement membrane (basal lamina)
What does the basement membrane consist of (2 parts)
Basal Lamina
Reticular lamina
Classify the types of epithelia
Simple squamous
Simple cuboidal
Simple columnar
Stratified squamous
Stratified cuboidal
Stratified columnar
Pseudostratified columnar
Transitional
Glandular epithelia
Function of simple squamous
Thin and delicate
Located in places like alveoli and endothelium
Involved in diffusion, Absorption and secretion
Nucleus usually appears squashed
Function of stratified squamous epithelium
Handle Mechanical stress from abrasion
Usually keratinized
Locations of keratinized stratified squamous epithelium
Exposed body surfaces
Living of the mouth oesophagus ants
Microvilli vs cilia
Microvilli found mostly in intestine to increase surface area for absorption while cilia is usually found mostly in respiratory tract to move the mucus