Epithelial Neoplasia Flashcards
5 characteristics of a benign tumour
- Usually Slow growing
- Cells uniform
- Encapsulated
- Grow by expansion
- Do not metastasise
Example of a benign epithelial tumour of the oral cavity
Squamous Cell Papilloma
2 examples of papillomas
- Squamous cell papilloma
- Verrucis vulgaris
What determines the diagnostic difference betweeen verruca vulgaris, and Squamous cell papilloma?
HPV detected - verruca vulgaris
No HPV detected - Squamous papilloma
Papillomas are often considered to be either virally induced hyperplasia or a benign neoplasm
True or false
True
What is often associated with the aetiology of papilloma lesions
HPV
Oral Squamous Papillomas are Premalignant
True or false
False.
Verrucas often regress spontaneously
True or false
True, especially in children
Bening epithelial neoplasm which often occurs on the lip (never intra-orally). May resemble SCC.
Keratoacanthoma
An invasive epithelial neoplasm with varying degrees of squamous differentiation and a propensity to early and extensive lymph node metastases, occurring predominantly in alcohol and tobacco using adults in the 5th to 6th decades of life.
Squamous Cell Carcinoma
What are the three most common locations for SCC
- Lower lip
- Lateral and ventral tongue
- Floor of mouth
5 major risk factors for OSCC
- Tobacco
- Alcohol
- Betel quid
- Sunlight, radiation, immune deficiency
- Marajuana
Do well differentiated tumours have a good or bad prognosis?
Better than poorly differentiated
If a patient has a suspected OSCC, what investigations would you carry out to include in referral
- Visual exam
- Tactile exam
- Lymph node exam
- Mouth opening
