Epithelial Cells (Locations, Purposes, Parts, Junctions) Flashcards

1
Q

Where is epithelial tissue found

A

Body surface and lining of hollow organs, cavities and ducts, as well as forming certain glands

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2
Q

What are the purposes of epithelial tissue

A

Limiting or aiding transfer, secretion onto a free surface, protection from abrasion

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3
Q

What are the two different cytoskeleton components

A

Actin Microfilaments and Keratin Intermediate Filaments

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4
Q

Microfilaments are predominantly composed of…

A

Actin

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5
Q

Intermediate filaments are predominantly composed of…

A

Keratin

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6
Q

What do microfilaments do?

A

Provide shape and strength to the cell and initiate cell movement

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7
Q

What do intermediate filaments do?

A

Provide shape and strength to the cell and move material around the cytoplasm

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8
Q

How do tight cell junctions hold cells together?

A

They “stitch” them together near the apical end of the cell with claudin and occludin

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9
Q

Will a tight cell junction allow for ions to pass between cells?

A

No, they are electrically tight

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10
Q

What are tight cell junctions made out of?

A

Claudin and Occludin

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11
Q

The gap within an adherence cell junction is spanned by what protein?

A

Cadherin

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12
Q

____ helps ____ bind to ____ ____in an adherence cell junction

A

Catenin helps bind Cadherin to Actin Microfilament in an adherence cell junction

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13
Q

A gap cell junction is formed by a combination of six ____ to form one ____ between cells

A

A gap cell junction is formed by a combination of six connexins to form one connexon/hemichannel between cells

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14
Q

Gap junctions form ___ between cells which allow transfer between cells

A

Gap junctions form tunnels between cells which allow transfer between cells

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15
Q

Desmosomes cell junctions look like what?

A

Buttons

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16
Q

The gap within a desmosome cell junction is spanned by what protein?

A

Cadherin

17
Q

___ links to ___ ___ ___ in a desmosome cell junction

A

Cadherin links to keratin intermediate filaments in a desmosome cell junction

18
Q

Hemidesmosome cell junctions bind to what membrane?

A

The basement membrane

19
Q

Hemidesmosome cell junctions look like what?

A

Buttons

20
Q

Hemidesmosome cell junctions bind to what cytoskeleton component?

A

Keratin intermediate filaments

21
Q

The gap between the basement membrane and a hemidesmosome button are bridged by what?

A

Integrin

22
Q

What does a hemidesmosome cell junction bind to in the basement membrane

A

Laminin

23
Q

Epithelial cells anchor to the ___

A

Basement membrane

24
Q

The basement membrane is comprised of ___ lamina and ___ lamina

A

Basal lamina and Reticular lamina

25
Q

The basal lamina is made from proteins supplied by ___

A

Epithelial cells

Which produce collagen, laminin, proteoglycans, glycoproteins etc.

26
Q

The reticular lamina is made from fibrous proteins supplied by ___

A

Fibroblasts in the connective tissue (Which produce fibronectin, collagen etc.)

27
Q

Do epithelial cells bind to the basal lamina or the reticular lamina?

A

Basal lamina

28
Q

Can epithelial tissue contain blood vessels?

A

No

29
Q

Can epithelial tissue contain nerves?

A

Yes

30
Q

How do epithelial cells gain nutrients and dispel waste?

A

The nutrients and waste diffuse into and out of epithelial cells through the basement membrane