Epithelial Cells (Locations, Purposes, Parts, Junctions) Flashcards

1
Q

Where is epithelial tissue found

A

Body surface and lining of hollow organs, cavities and ducts, as well as forming certain glands

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2
Q

What are the purposes of epithelial tissue

A

Limiting or aiding transfer, secretion onto a free surface, protection from abrasion

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3
Q

What are the two different cytoskeleton components

A

Actin Microfilaments and Keratin Intermediate Filaments

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4
Q

Microfilaments are predominantly composed of…

A

Actin

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5
Q

Intermediate filaments are predominantly composed of…

A

Keratin

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6
Q

What do microfilaments do?

A

Provide shape and strength to the cell and initiate cell movement

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7
Q

What do intermediate filaments do?

A

Provide shape and strength to the cell and move material around the cytoplasm

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8
Q

How do tight cell junctions hold cells together?

A

They “stitch” them together near the apical end of the cell with claudin and occludin

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9
Q

Will a tight cell junction allow for ions to pass between cells?

A

No, they are electrically tight

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10
Q

What are tight cell junctions made out of?

A

Claudin and Occludin

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11
Q

The gap within an adherence cell junction is spanned by what protein?

A

Cadherin

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12
Q

____ helps ____ bind to ____ ____in an adherence cell junction

A

Catenin helps bind Cadherin to Actin Microfilament in an adherence cell junction

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13
Q

A gap cell junction is formed by a combination of six ____ to form one ____ between cells

A

A gap cell junction is formed by a combination of six connexins to form one connexon/hemichannel between cells

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14
Q

Gap junctions form ___ between cells which allow transfer between cells

A

Gap junctions form tunnels between cells which allow transfer between cells

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15
Q

Desmosomes cell junctions look like what?

A

Buttons

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16
Q

The gap within a desmosome cell junction is spanned by what protein?

17
Q

___ links to ___ ___ ___ in a desmosome cell junction

A

Cadherin links to keratin intermediate filaments in a desmosome cell junction

18
Q

Hemidesmosome cell junctions bind to what membrane?

A

The basement membrane

19
Q

Hemidesmosome cell junctions look like what?

20
Q

Hemidesmosome cell junctions bind to what cytoskeleton component?

A

Keratin intermediate filaments

21
Q

The gap between the basement membrane and a hemidesmosome button are bridged by what?

22
Q

What does a hemidesmosome cell junction bind to in the basement membrane

23
Q

Epithelial cells anchor to the ___

A

Basement membrane

24
Q

The basement membrane is comprised of ___ lamina and ___ lamina

A

Basal lamina and Reticular lamina

25
The basal lamina is made from proteins supplied by ___
Epithelial cells | Which produce collagen, laminin, proteoglycans, glycoproteins etc.
26
The reticular lamina is made from fibrous proteins supplied by ___
Fibroblasts in the connective tissue (Which produce fibronectin, collagen etc.)
27
Do epithelial cells bind to the basal lamina or the reticular lamina?
Basal lamina
28
Can epithelial tissue contain blood vessels?
No
29
Can epithelial tissue contain nerves?
Yes
30
How do epithelial cells gain nutrients and dispel waste?
The nutrients and waste diffuse into and out of epithelial cells through the basement membrane