Epithelial Flashcards
Probably caused by HPV; over 100 types identified; 6 and 11 are most commonly associated
squamous papilloma
any site, with the tongue and soft palate most frequently involved; typically solitary; usually pedunculated; variable color
squamous papilloma
papillary proliferation of hyperkeratotic stratified squamous epithelium; supported by finger like projections of fibrovascular connective tissue
squamous papilloma
squamous papillomas of the _ may behave differently
larynx
typically a benign skin lesion induced by HPV 2, 4, 6 and 40; relatively contagious with potential for autoinoculation
verruca vulgaris (common wart)
most commonly in children; skin of hands; more commonly sessile; variable color
verruca vulgaris
oral lesions uncommon; often indistinguishable from squamous papilloma; oral lesions typically appear white
verruca vulgaris
papillary, hyperkeratotic proliferation of epithelium; rete ridges appear to converge toward the center of the lesion; course keratohyaline granules and koilocytosis
verruca vulgaris
also known as “venereal warts”; caused by several strains of HPV, including types 2, 6, 11, 16, 18
condyloma acuminatum
typically a genital lesion; oral lesions -multiple, sessile, cauliflower surface
condyloma acuminatum
common lesion of the elderly; unknown etiology but correlated with sun exposure; may be hereditary
seborrheic keratosis
exclusively a skin lesion; face, trunk, extremities; tan to brown, roughened plaques; “stuck on” appearance
seborrheic keratosis
seborrheic keratosis; 30% blacks; multiple brown to black papules
dermatosis papulosa nigra
exophytic, papillary proliferation of basaloid cells; horn cysts and pseudo-horn cysts
seborrheic keratosis
multiple seborrheic keratoses may be an indicator of internal malignancy- _ sign
Leser-Trelat sign
common lesion of facial skin; unknown etiology; significance based upon the clinical resemblance to the more serious basal cell carcinoma
sebaceous hyperplasia
> 40 yrs; white, yellow or normal color umbilicated papule, usually
sebaceous hyperplasia
fordyce granules have same histo as _
sebaceous hyperplasia
benign lesion secondary to chronic sun exposure; no intraoral counterpart; patients who have facial ephelides (freckles) are more likely to develop later in life
actinic lentigo
elderly whites; facial skin, dorsum of hands and arms; brown to tan, well demarcated macules; no change on sun exposure (unlike ephelis)
actinic lentigo
common oral mucosal lesion of unknown etiology; lip lesions may be associated with actinic exposure; F>M; commonly affects the lower lip vermilion zone
oral melanotic macule
tan to dark brown macule usually less than 7mm; no change with sun exposure; oral
oral melanotic macule
Oral melanotic macule- histo may be necessary to rule out _
melanoma
benign proliferation of nevus cells, which are derived from neural crest and are related to melanocytes; acquired or congenital; intraoral lesions are uncommon
acquired melanocytic nevus (mole)
F>M; begin to occur in childhood; 10-40 may be present in the average adult
acquired melanocytic nevus
3 stages of acquired melanocytic nevus?
junctional, compound, intradermal
intraoral; palate, gingiva; less papillomatous; may never show pigmentation
acquired melanocytic nevus
proliferation of nevus cells that vary in morphology depending upon their depth; superficially arranged in theques
acquired melanocytic nevus