Allergies/Immunologic

Question 1

_ aphthae (recurrent aphthous stomatitis)- 3mm ulcer with yellow-white membrane and erythematous halo; unattached mucosa

Answer 1

minor

Question 2

_ aphthae (recurrent aphthous stomatitis) - larger (up to 3cm) and longer duration (2-6 weeks); may heal with scar; HIV

Answer 2

major

Question 3

_ aphthae- numerous, small lesions; predominantly non-keratinized mucusa

Answer 3

herpetiform

Question 4

Combination of oral aphthous-like ulcerations, and ocular inflammation (anterior and posterior uveitis); probably an immunogenic process with a strong association to certain HLA types

Answer 4

Behcet’s Syndrome

Question 5

Oral ulcerations of _: aphthous-like ulcerations located primarily on soft palate and oropharynx

Answer 5

Behcet’s Syndrome

Question 6

cutaneous lesions of _: erythema nodosum, papulopustular lesions, acneform lesions

Answer 6

Behcet’s syndrome

Question 7

Behcet’s syndrome- histo similar to aphthous with leukocytoclastic vasculitis

Answer 7

Behcet’s

Question 8

F>M, blacks>whites, typically occurs during the 3rd and 4th decades; dyspnea, dry cough; fever, malaise; fatigue, arthralgia; lymphadenopathy

Answer 8

sarcoidosis

Question 9

skin lesions of _: lupus pernio and erythema nodosum

Answer 9

sarcoidosis

Question 10

_ of sarcoidosis: parotid enlargement, anterior uveitis, facial paralysis, fever

Answer 10

Heerfordt’s syndrome

Question 11

_ of sarcoidosis: arthralgia, bilateral hilar lymphadenopathy, erythema nodosum

Answer 11

lofgren’s syndrome

Question 12

_ of sarcoidosis: langhans’ or foreign body giant cells; schaumann bodies; asteroid bodies

Answer 12

granulomatous inflammation

Question 13

Highly variable presentation; involvement of lips- cheilitis granulomatosa

Answer 13

orofacial granulomatosis

Question 14

_ of orofacial granulomatosis: non-tender swelling, usually involving lips; Bell’s palsy; fissured tongue

Answer 14

Melkersson-Rosenthal syndrome

Question 15

_ granulomas may be sparse in orofacial granulomatosis

Answer 15

non-necrotizing

Question 16

Necrotizing granulomatous process; classically affects upper airway, lungs, kidneys; epistaxis, pain, nasal obstruction

Answer 16

Wegener’s granulomatosis

Question 17

multisystemic vasculitis of small arteries and veins; occasionally involves the eyes, ears and skin

Answer 17

wegener’s

Question 18

oral lesions of _: large, chronic ulcers and “strawberry gums”

Answer 18

wegener’s

Question 19

may present with systemic signs or symptoms; multiple ones of erythema or aphthous-like eruptions

Answer 19

anaphylactic stomatitis

Question 20

localized erythema and edema; vesiculoerosive lesions

Answer 20

fixed drug reaction

Question 21

_ allergic contact stomatitis- burning, erythema, occasional vesicles

Answer 21

acute

Question 22

_ allergic contact stomatitis- erythematous or white, may extend beyond the oral cavity

Answer 22

chronic

Question 23

_ reaction more generalized (stomatitis from artificial cinnamon): pain, burning, erythema; frequently will affect the gingiva; may extend to perioral tissue

Answer 23

toothpaste

Question 24

_ (cinnamon flavoring) often localized to the buccal mucosa or lateral borders of the tongue: ragged hyperkeratosis; erythematous base

Answer 24

gum, candy

Question 25

chronic reactions resemble localized lichen planus-like lesions

Answer 25

chronic (lichenoid) oral mucosal contact reactions to dental amalgam

Question 26

posterior buccal mucosa or lateral surfaces of the tongue; white and/or erythematous, often with peripheral striae

Answer 26

contact reactions to amalgam

Question 27

3 primary mechanisms of _: hypersensitivity rxn due to IgE mediated mast cell degranulation; associated with ACE inhibitors, secondary to increased bradykinin levels; lack of or inactive C1 esterase inhibitor (inherited or acquired)

Answer 27

angioedema (Quincke's disease)

Question 28

enlargement of relatively rapid onset; pruritis, erythema; respiratory involvement may be life threatening

Answer 28

angioedema

Question 29

angioedema: _ and _ don't respond to antihistamines

Answer 29

ACE inhibitor related and C1-INH deficient