enzymes and homeostasis Flashcards

1
Q

_______ glands secrete hormones directly into the blood

A

endocrine

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2
Q

_______ glands secrete hormones into ducts

A

exocrine

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3
Q

the protein portion of an enzyme is called the ______

A

apoenzyme

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4
Q

the model that considers the substrate and active site to be a perfect fit for each other

A

lock and key

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5
Q

this enlargement of the throat can occur due to either hypothyroidism OR hyperthyroidism

A

goiter

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6
Q

maintaining the internal environment of the body at equilibrium

A

homeostasis

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7
Q

insulin is an example of a ______ hormone

A

peptide

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8
Q

every enzyme has an optimal ____ at which it will work in the body. The exact value of this will depend upon where in the body that enzyme is functioning. Values too far above OR below optimal will result in the denaturation of the enzyme

A

pH

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9
Q

a factor affecting the rate of a chemical reaction

A

temperature

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10
Q

organic, but non-protein cofactors are often derived from these substances

A

vitamins

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11
Q

in order to cool your body, blood vessels near the surface of the skin will ______

A

dilate

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12
Q

many ______ are inhibitors that permanently bind to the active site of enzymes, rendering them inactive

A

poisons

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13
Q

an ______ occurs to correct the situation when a receptor detects that conditions in the body are out of the normal range

A

adaptive response

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14
Q

all enzymes names end in this suffix

A

ase (sometimes “in”)

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15
Q

enzyme activity can be greatly reduced when temperatures get too _____. this situation is irreversible

A

hot

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16
Q

components of the body which detect light

A

photoreceptors

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17
Q

increasing this factor will increase the rate of a chemical reaction

A

surface area

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18
Q

all of the body’s sensory receptors are connected to the ________ system

A

nervous

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19
Q

the portion of an enzyme that binds with the substrate

A

active site

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20
Q

cofactors can belong to this group of substances

A

metals

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21
Q

components of the body which detect chemical changes

A

chemoreceptors

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22
Q

a ______ increases the rate of a chemical reaction by lowering the activation energy

A

catalyst

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23
Q

when the product of an enzyme catalyzed reaction binds to the ______ site on the enzyme, it causes a change to the shape of the active site and the enzyme becomes temporarily inactive

A

allosteric

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24
Q

this word is what happens to a protein when its shape is changed by being exposed to heat or certain chemicals

A

denature

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25
_______ like mercury and lead can cause the denaturation of enzymes
heavy metals
26
_______ are chemical messengers which help cells communicate with each other
hormones
27
an organic, but non-protein substance (eg. vitamin) which place a role in forming a functioning enzyme
coenzyme
28
this word refers to the combination of all the chemical reactions that are occurring within an organism
metabolism
29
components of the body which detect changes in blood pressure
baroreceptors (pressoreceptors)
30
the idea that the active site modifies its shape as it forms the enzyme-substrate complex
induced fit
31
the receptors for regulating body temperature are located in this part of the brain
hypothalamus
32
the enzyme maltase decomposes the sugar ______
maltose
33
the _____ energy is the amount of energy that is required to get a chemical reaction started
activation
34
a solution with a higher _______ will provide a faster reaction rate than a solution with one that is lower
concentration
35
________ feedback systems are very rare in humans, but are present in situations like childbirth and breastfeeding
positive
36
enzyme activity can be reduced when temperatures become too _____, however this situation can be reversed
cold
37
this enzyme catalyzes the decomposition of hydrogen peroxide
catalase
38
this element is required for the production of thyroxin
iodine
39
if your body temperature drops below normal, your brain may direct your body to start involuntary muscle contractions which makes you start to _______
shiver
40
blood pressure, blood pH, and blood glucose levels are all part of _______ feedback systems where the correction of the level which is out of range leads to a SLOWING or CEASING of the corrective measure
negative
41
in order to function properly, enzymes require an additional substance called a _______, which are typically inorganic ions of metals
cofactor
42
components of the body which detect temperature changes
thermoreceptors
43
the term metabolic ______ refers to a sequence of enzyme-catalyzed chemical reactions which are all linked to each other
pathway
44
metabolic rate is controlled by the hormone thyroxin which is produced by the _____ gland
thyroid
45
a word used to describe a substance which will combine with the active site of an enzyme during a reaction
substrate
46
enzymes are said to be ______ because each enzyme catalyzes only one type of reaction
specific
47
in an enzyme catalyzed reaction, reaction rate will continue to increase with the addition of more substrate until all enzyme active sites are ______. the addition of more substrate beyond this point will result in no increase in reaction rate
saturated
48
lipid based hormones are composed of ______
steroids
49
a biological catalyst is called a(n) _______
enzyme
50
_______ hormones act inside of the nucleus by binding to sites on the DNA.
steroid
51
_______ hormones cannot pass through the cell membrane and must bind with a receptor on the cell's surface.
peptide
52
describe the role of enzymes in a metabolic pathway
- it is a sequence of enzyme-catalyzed chemical reactions which are all linked to each other - they begin with a particular reactant and terminate with an end product - each enzyme controls one reaction only; therefore it is specific for that reaction
53
what is the difference between lock & key and induced fit?
lock and key= enzyme has a specific shape which allows the substrate to fit (ex. you can't use your house key to open your car door) induced fit= some active sites undergo a slight change in shape in order to accommodate a substrate
54
how does negative feedback inhibition affect a enzyme catalyzed reaction?
it occurs when the end product of a reaction interferes with the enzyme that helped produce it. (binds to allosteric site) Therefore, the enzyme changes shape and can't catalyze the reaction anymore.
55
what's the difference between a catalyst and an enzyme?
- Catalysts are substances that increase or decrease the rate of a chemical reaction. - Enzymes are biological catalysts, which speed up reactions in living things
56
what are the 4 ways of increasing the rate of a chemical reaction?
surface area, temperature, concentration, and using a catalyst
57
what is the name for the functional enzyme?
holoenzyme
58
Describe positive feedback systems
Childbirth and breastfeeding are examples of positive feedback systems. During contractions, the hormone oxytocin continues to be made so that the contractions become closer together. This is the opposite of negative feedback systems where result of a reaction is reduced to bring the system back to a stable state
59
Do enzymes change after a reaction?
no
60
why is homeostasis important?
it maintains the optimal conditions for enzyme activity throughout the body as well as proper cell function
61
what is significant about the allosteric site?
it controls the amount of products being produced (can increase or decrease)
62
what would make an enzyme graph go down?
it was denatured or an inhibitor was present
63
Why is thyroxine important?
it is the main hormone secreted into our blood and plays vital roles in digestion, heart and muscle function, brain development. Too much or too little thyroxine can cause hyperthyroidism or hypothyroidism
64
What part of the graph do you choose if a question asks you about reaction rate?
Pick the high point of the graph
65
What part of the graph do you choose if a question asks you about the time for a certain amount of product?
Pick the low point of the graph
66
what is another word for metabolic rate?
resting rate
67
what are two things your cells use up when idling (resting)?
oxygen and glucose
68
difference between a fast & slow metabolic rate
fast rate = more oxygen and glucose | slow rate = less oxygen and glucose
69
what is the pituitary gland?
it works with the hypothalamus and plays a major role in regulating vital body functions
70
How could you tell the difference between a steroid or a protein going into a cell?
- if it is a steroid it would go straight through to the nucleus because it is lipid-based and easily goes through the cell membrane - if it is a protein it would have to bind to a receptor
71
what is something that binds permanently to an enzyme?
poison
72
What does cyanide stop the pathway of?
ATP